Induction of apoptosis and regulation ofMicroRNA expression by (2E,6E)-2,6-bis-(4-hydroxy-3-methoxybenzylidene)- cyclohexanone (BHMC) treatment on MCF-7 breast cancer cells
(2E,6E)-2,6-bis-(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) is a synthetic curcumin analogue, which has been reported to possess anti-tumor, anti-metastatic, and anti-invasion properties on estrogen receptor (ER) negative breast cancer cells in vitro and in vivo. However, the cytotoxic eff...
| Main Authors: | Yeap, S. K., Ali, N. M., Akhtar, M. N., Razak, N. A., Chong, Z. X., Ho, W. Y., Boo, L., Zareen, S., Kurniawan, T. A., Avtar, R., Ng, S. Y. L., Ong, A. H. K. |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/32769/ http://umpir.ump.edu.my/id/eprint/32769/1/Induction%20of%20apoptosis%20and%20regulation%20ofMicroRNA%20expression%20by%20%282E%2C6E%29-2%2C6-bis-%284-hydroxy-3-methoxybenzylidene%29-%20cyclohexanone%20%28BHMC%29%20treatment.pdf |
Similar Items
Induction of apoptosis and regulation of MicroRNA expression by (2E,6E)-2,6-bis-(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) treatment on MCF-7 breast cancer cells
by: Yeap, Swee Keong, et al.
Published: (2021)
by: Yeap, Swee Keong, et al.
Published: (2021)
The In Vivo Anti-Tumor Effect of Curcumin Derivative (2E,6E)-2,6-bis(4-hydroxy-3-methoxybenzylidene) Cyclohexanone (BHMC) on 4T1 Breast Cancer Cells
by: Nursyamirah, Abd Razak, et al.
Published: (2017)
by: Nursyamirah, Abd Razak, et al.
Published: (2017)
The in vivo anti-tumor effect of curcumin derivative (2 E,6 E)-2,6-bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone (BHMC) on 4T1 breast cancer cells
by: Razak, Nursyamirah Abd, et al.
Published: (2017)
by: Razak, Nursyamirah Abd, et al.
Published: (2017)
Development and validation of a bioanalytical method for quantification of 2,6-bis-(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) in rat plasma
by: Lee, Yu Zhao, et al.
Published: (2012)
by: Lee, Yu Zhao, et al.
Published: (2012)
Cytotoxic effect of 2,6-bis(4-hydroxy-3-methoxybenzylidene) cyclohexanone (BHMC) and curcumin on human liver cancer cells, HepG2
by: Syed Alwi, Sharifah Sakinah, et al.
Published: (2019)
by: Syed Alwi, Sharifah Sakinah, et al.
Published: (2019)
Cytotoxicity and apoptosis effects of curcumin analogue (2E,6E)-2,6-Bis(2,3-Dimethoxybenzylidine) cyclohexanone (DMCH) on human colon cancer cells HT29 and SW620 in vitro
by: Nurul Fattin, Che Rahim, et al.
Published: (2021)
by: Nurul Fattin, Che Rahim, et al.
Published: (2021)
Antinociceptive activity of a synthetic curcuminoid analogue, 2,6-bis-(4-hydroxy-3-methoxybenzylidene)cyclohexanone, on nociception-induced models in mice.
by: Lee, Ming Tatt, et al.
Published: (2012)
by: Lee, Ming Tatt, et al.
Published: (2012)
Synthesis, Spectral Characterization and Crystal Structure of
(E)-4- Hydroxy-N -(2-methoxybenzylidene) benzohydrazide
by: Rassem, Hesham H. A., et al.
Published: (2016)
by: Rassem, Hesham H. A., et al.
Published: (2016)
1-[(E)-(3-Hydroxy-4-methoxybenzylidene)amino]-
3-methylthiourea
by: Arafath, Md. Azharul, et al.
Published: (2016)
by: Arafath, Md. Azharul, et al.
Published: (2016)
Pattern of hmlh1, hmsh2 and hmsh6 expressions and clinical characteristics in Malaysian colorectal carcinoma cases
/ Khoo Joon Joon
by: Khoo, Joon Joon
Published: (2011)
by: Khoo, Joon Joon
Published: (2011)
Crystal structure of (E)-2-(4-hydroxy-3-methoxybenzylidene)-6-methoxy-3,4-dihydronaphthalen-1(2H)-one, C19H18O4
by: El-Sayed, Nahed Nasser Eid, et al.
Published: (2016)
by: El-Sayed, Nahed Nasser Eid, et al.
Published: (2016)
Cytotoxicity, proliferation and migration effects of 2,6-bis-(4-hydroxyl-3-methoxybenzylidine)cyclohexanone (BHMC) on human liver cancer, HepG2 cells
by: Mohd Shafiee, Muhammad Aminuddin, et al.
Published: (2024)
by: Mohd Shafiee, Muhammad Aminuddin, et al.
Published: (2024)
Development of polymer-assisted nanoparticles and nanogels for cancer therapy: An update
by: Bibi Noorheen, H. M. N., et al.
Published: (2021)
by: Bibi Noorheen, H. M. N., et al.
Published: (2021)
p53-Mdm2 interaction targeted therapy by Nutlin-3 on nasopharyngeal carcinoma cells / Voon Yee Lin
by: Voon, Yee Lin
Published: (2016)
by: Voon, Yee Lin
Published: (2016)
Green synthesis of Fe3O4 nanoparticles for hyperthermia, magnetic resonance imaging and 5-fluorouracil carrier in potential colorectal cancer treatment
by: Yusefi, Mostafa, et al.
Published: (2021)
by: Yusefi, Mostafa, et al.
Published: (2021)
Exploring the ‘Dormancy Activation Switch’ in the tumour microenvironment for metastatic lung cancer: The possible role of MicroRNA
by: Amnani, A., et al.
Published: (2021)
by: Amnani, A., et al.
Published: (2021)
Association between autophagy and KRAS mutation with
clinicopathological variables in colorectal cancer patients
by: Awi, Noel Jacques, et al.
Published: (2021)
by: Awi, Noel Jacques, et al.
Published: (2021)
High expression of LC3A, LC3B, and p62/SQSTM1 autophagic
proteins in human colonic ganglion cells
by: Awi, Noel Jacques *, et al.
Published: (2020)
by: Awi, Noel Jacques *, et al.
Published: (2020)
Potential use of plasma focus radiation sources in superficial cancer therapy
by: Poh, H. S., et al.
Published: (2020)
by: Poh, H. S., et al.
Published: (2020)
5-Fluorouracil encapsulated chitosan-cellulose fiber bionanocomposites: Synthesis, characterization and in vitro analysis towards colorectal cancer cells
by: Yusefi, Mostafa, et al.
Published: (2021)
by: Yusefi, Mostafa, et al.
Published: (2021)
The molecular targets and anti-invasive effects of 2,6-bis-(4-hydroxyl-3methoxybenzylidine) cyclohexanone or BHMC in MDA-MB-231 human breast cancer cells
by: Harun, Siti Nor Aini, et al.
Published: (2018)
by: Harun, Siti Nor Aini, et al.
Published: (2018)
Interplay of autophagy and cancer stem cells in hepatocellular carcinoma
by: Wong, M. M. T., et al.
Published: (2021)
by: Wong, M. M. T., et al.
Published: (2021)
Transient Multiple Removal and Subsequent Reimplantation
of Abdominal and Retroperitoneal Organs with Multisystemic
Neoplastic Lesions
by: Shcherbyuk, A.N., et al.
Published: (2017)
by: Shcherbyuk, A.N., et al.
Published: (2017)
Corrigendum to (Unmet Supportive Care Needs among Breast Cancer Survivors of Community-Based Support Group in Kuching, Sarawak)
by: Fong, Emmanuel Joseph, et al.
Published: (2017)
by: Fong, Emmanuel Joseph, et al.
Published: (2017)
5-fluorouracil loaded magnetic cellulose bionanocomposites for potential colorectal cancer treatment
by: Yusefi, Mostafa, et al.
Published: (2021)
by: Yusefi, Mostafa, et al.
Published: (2021)
A synthetic curcuminoid analogue, 2,6-Bis-4-(Hydroxyl-3-Methoxybenzylidine)-Cyclohexanone (BHMC) ameliorates acute airway inflammation of allergic asthma in ovalbumin-sensitized mice
by: Tham, Chau Ling, et al.
Published: (2021)
by: Tham, Chau Ling, et al.
Published: (2021)
Short Review: Phytofabrication of zinc oxide nanoparticles for anticancer applications
by: Siti Nur Amalina, M. S., et al.
Published: (2021)
by: Siti Nur Amalina, M. S., et al.
Published: (2021)
Anti-metastasis Effects and Mechanism of Action of Curcumin Analog (2E,6E)-2,6-bis(2,3-dimethoxybenzylidene) Cyclohexanone (DMCH) on the SW620 Colorectal Cancer Cell Line
by: Che Rahim, Nurul Fattin, et al.
Published: (2025)
by: Che Rahim, Nurul Fattin, et al.
Published: (2025)
Tricistronic expression of MOAP-1, Bax and RASSF1A in cancer cells enhances chemo-sensitization that requires BH3L domain of MOAP-1
by: Lee, Y. H., et al.
Published: (2020)
by: Lee, Y. H., et al.
Published: (2020)
Association of Palb2 variants with risk to breast cancer and molecular characterisation of PALB2 tumours / Ng Pei Sze
by: Ng, Pei Sze
Published: (2021)
by: Ng, Pei Sze
Published: (2021)
Cytotoxicity and apoptosis effects of curcumin analogue (2E,6E)-2,6-Bis(2,3-Dimethoxybenzylidine) Cyclohexanone (DMCH) on human colon cancer cells HT29 and SW620 in vitro
by: Che Rahim, Nurul Fattin, et al.
Published: (2021)
by: Che Rahim, Nurul Fattin, et al.
Published: (2021)
Chemical constituents and cytotoxic properties of Goniothelamus Macrophyllus / Hamidah Sahibul Anwar
by: Sahibul Anwar, Hamidah
Published: (2008)
by: Sahibul Anwar, Hamidah
Published: (2008)
The functional −94 insertion/deletion ATTG polymorphism in the promoter region of NFKB1 gene increases the risk of sporadic colorectal cancer
by: Mohd Shafi’i, Mohd Suzairi, et al.
Published: (2013)
by: Mohd Shafi’i, Mohd Suzairi, et al.
Published: (2013)
Enrichment of Colorectal Cancer Stem Cells by Spheroidal Culture and Gene Expression Analysis of Selected ABC Transporters
by: Vimalan, Rengganaten
Published: (2016)
by: Vimalan, Rengganaten
Published: (2016)
Overexpression of WNT2 and TSG101 genes in colorectal
carcinoma
by: Ma, Xiang Ru, et al.
Published: (2008)
by: Ma, Xiang Ru, et al.
Published: (2008)
Synthesis, NMR spectroscopy and crystal structures
studies of 2-amino-N-(2-hydroxy-3-methoxybenzylidene) aniline
by: Al-Douh, Mohammed Hadi, et al.
Published: (2009)
by: Al-Douh, Mohammed Hadi, et al.
Published: (2009)
Oncogenic role of cancer-associated fibroblast secretion in endometrial cancer progression in vitro and in vivo / Kavita S. Subramaniam
by: Kavita, S. Subramaniam
Published: (2016)
by: Kavita, S. Subramaniam
Published: (2016)
Cognitive changes and their impact on functioning at work: A qualitative study on women with breast cancer / Maryam Hafsah Mohammed Selamat
by: Maryam Hafsah, Mohammed Selamat
Published: (2016)
by: Maryam Hafsah, Mohammed Selamat
Published: (2016)
Antiproliferative, antimetastatic properties of phyllanthus specieson breastand lungcancer cell linesand their targetted signal transduction pathways / Lee Sau Har
by: Lee, Sau Har
Published: (2013)
by: Lee, Sau Har
Published: (2013)
Depression, anxiety, and type d personality in newly diagnosed breast cancer patients: a quasi-prospective association study / Beatrice Ng Andrew
by: Beatrice, Ng Andrew
Published: (2014)
by: Beatrice, Ng Andrew
Published: (2014)
Similar Items
-
Induction of apoptosis and regulation of MicroRNA expression by (2E,6E)-2,6-bis-(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) treatment on MCF-7 breast cancer cells
by: Yeap, Swee Keong, et al.
Published: (2021) -
The In Vivo Anti-Tumor Effect of Curcumin Derivative (2E,6E)-2,6-bis(4-hydroxy-3-methoxybenzylidene) Cyclohexanone (BHMC) on 4T1 Breast Cancer Cells
by: Nursyamirah, Abd Razak, et al.
Published: (2017) -
The in vivo anti-tumor effect of curcumin derivative (2 E,6 E)-2,6-bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone (BHMC) on 4T1 breast cancer cells
by: Razak, Nursyamirah Abd, et al.
Published: (2017) -
Development and validation of a bioanalytical method for quantification of 2,6-bis-(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) in rat plasma
by: Lee, Yu Zhao, et al.
Published: (2012) -
Cytotoxic effect of 2,6-bis(4-hydroxy-3-methoxybenzylidene) cyclohexanone (BHMC) and curcumin on human liver cancer cells, HepG2
by: Syed Alwi, Sharifah Sakinah, et al.
Published: (2019)