Sigmoid pid based adaptive safe experimentation dynamics algorithm of portable duodopa pump for parkinson’s disease patients
This paper emphasizes on the development of an appropriate closed-loop control strategy for traditional portable duodopa pump (PDP); thereby ensuring an automated drug infusion without wearing off. In particular, a sigmoid proportional integral derivative (SPID) controller is adopted to control the...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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IAES
2021
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| Online Access: | http://umpir.ump.edu.my/id/eprint/32720/ http://umpir.ump.edu.my/id/eprint/32720/1/Sigmoid%20pid%20based%20adaptive%20safe%20experimentation%20dynamics%20algorithm.pdf |
| _version_ | 1848824094382882816 |
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| author | Razak Ramesh, N. H. A. Ghazali, M. R. Ahmad, M. A. |
| author_facet | Razak Ramesh, N. H. A. Ghazali, M. R. Ahmad, M. A. |
| author_sort | Razak Ramesh, N. H. A. |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | This paper emphasizes on the development of an appropriate closed-loop control strategy for traditional portable duodopa pump (PDP); thereby ensuring an automated drug infusion without wearing off. In particular, a sigmoid proportional integral derivative (SPID) controller is adopted to control the blood plasma level of dopamine. The parameters of SPID controller are tuned using the adaptive safe experimentation dynamics (ASED) algorithm. The efficiency of the suggested SPID-ASED is evaluated by concerning the convergence plot of the cost function, the amount of dopamine in the blood plasma (BP) of the patient, the statistical analysis of cost function, norm of error and norm of input, and time responses specifications. The simulation results show that the proposed SPID-ASED outperforms the standard PID controller in terms of better control accuracy with minimum overshoot and settling time. |
| first_indexed | 2025-11-15T03:07:34Z |
| format | Article |
| id | ump-32720 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T03:07:34Z |
| publishDate | 2021 |
| publisher | IAES |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-327202022-01-06T03:01:24Z http://umpir.ump.edu.my/id/eprint/32720/ Sigmoid pid based adaptive safe experimentation dynamics algorithm of portable duodopa pump for parkinson’s disease patients Razak Ramesh, N. H. A. Ghazali, M. R. Ahmad, M. A. T Technology (General) TA Engineering (General). Civil engineering (General) TK Electrical engineering. Electronics Nuclear engineering This paper emphasizes on the development of an appropriate closed-loop control strategy for traditional portable duodopa pump (PDP); thereby ensuring an automated drug infusion without wearing off. In particular, a sigmoid proportional integral derivative (SPID) controller is adopted to control the blood plasma level of dopamine. The parameters of SPID controller are tuned using the adaptive safe experimentation dynamics (ASED) algorithm. The efficiency of the suggested SPID-ASED is evaluated by concerning the convergence plot of the cost function, the amount of dopamine in the blood plasma (BP) of the patient, the statistical analysis of cost function, norm of error and norm of input, and time responses specifications. The simulation results show that the proposed SPID-ASED outperforms the standard PID controller in terms of better control accuracy with minimum overshoot and settling time. IAES 2021-04 Article PeerReviewed pdf en cc_by_sa_4 http://umpir.ump.edu.my/id/eprint/32720/1/Sigmoid%20pid%20based%20adaptive%20safe%20experimentation%20dynamics%20algorithm.pdf Razak Ramesh, N. H. A. and Ghazali, M. R. and Ahmad, M. A. (2021) Sigmoid pid based adaptive safe experimentation dynamics algorithm of portable duodopa pump for parkinson’s disease patients. Bulletin of Electrical Engineering and Informatics, 10 (2). pp. 632-639. ISSN 2089-3191. (Published) https://doi.org/10.11591/eei.v10i2.2542 https://doi.org/10.11591/eei.v10i2.2542 |
| spellingShingle | T Technology (General) TA Engineering (General). Civil engineering (General) TK Electrical engineering. Electronics Nuclear engineering Razak Ramesh, N. H. A. Ghazali, M. R. Ahmad, M. A. Sigmoid pid based adaptive safe experimentation dynamics algorithm of portable duodopa pump for parkinson’s disease patients |
| title | Sigmoid pid based adaptive safe experimentation dynamics algorithm of portable duodopa pump for parkinson’s disease patients |
| title_full | Sigmoid pid based adaptive safe experimentation dynamics algorithm of portable duodopa pump for parkinson’s disease patients |
| title_fullStr | Sigmoid pid based adaptive safe experimentation dynamics algorithm of portable duodopa pump for parkinson’s disease patients |
| title_full_unstemmed | Sigmoid pid based adaptive safe experimentation dynamics algorithm of portable duodopa pump for parkinson’s disease patients |
| title_short | Sigmoid pid based adaptive safe experimentation dynamics algorithm of portable duodopa pump for parkinson’s disease patients |
| title_sort | sigmoid pid based adaptive safe experimentation dynamics algorithm of portable duodopa pump for parkinson’s disease patients |
| topic | T Technology (General) TA Engineering (General). Civil engineering (General) TK Electrical engineering. Electronics Nuclear engineering |
| url | http://umpir.ump.edu.my/id/eprint/32720/ http://umpir.ump.edu.my/id/eprint/32720/ http://umpir.ump.edu.my/id/eprint/32720/ http://umpir.ump.edu.my/id/eprint/32720/1/Sigmoid%20pid%20based%20adaptive%20safe%20experimentation%20dynamics%20algorithm.pdf |