Sigmoid PID based adaptive safe experimentation dynamics algorithm of portable duodopa pump for Parkinson’s disease patients

This paper emphasizes on the development of an appropriate closed-loop control strategy for traditional portable duodopa pump (PDP); thereby ensuring an automated drug infusion without wearing off. In particular, a sigmoid proportional integral derivative (SPID) controller is adopted to control the...

Full description

Bibliographic Details
Main Authors: Najwa Hidayah, Abdul Razak Ramesh, Mohd Riduwan, Ghazali, Mohd Ashraf, Ahmad
Format: Article
Language:English
Published: IAES 2021
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/32264/
http://umpir.ump.edu.my/id/eprint/32264/1/Sigmoid%20PID%20based%20adaptive%20safe%20experimentation%20dynamics%20algorithm.pdf
_version_ 1848823979087757312
author Najwa Hidayah, Abdul Razak Ramesh
Mohd Riduwan, Ghazali
Mohd Ashraf, Ahmad
author_facet Najwa Hidayah, Abdul Razak Ramesh
Mohd Riduwan, Ghazali
Mohd Ashraf, Ahmad
author_sort Najwa Hidayah, Abdul Razak Ramesh
building UMP Institutional Repository
collection Online Access
description This paper emphasizes on the development of an appropriate closed-loop control strategy for traditional portable duodopa pump (PDP); thereby ensuring an automated drug infusion without wearing off. In particular, a sigmoid proportional integral derivative (SPID) controller is adopted to control the blood plasma level of dopamine. The parameters of SPID controller are tuned using the adaptive safe experimentation dynamics (ASED) algorithm. The efficiency of the suggested SPID-ASED is evaluated by concerning the convergence plot of the cost function, the amount of dopamine in the blood plasma (BP) of the patient, the statistical analysis of cost function, norm of error and norm of input, and time responses specifications. The simulation results show that the proposed SPID-ASED outperforms the standard PID controller in terms of better control accuracy with minimum overshoot and settling time.
first_indexed 2025-11-15T03:05:44Z
format Article
id ump-32264
institution Universiti Malaysia Pahang
institution_category Local University
language English
last_indexed 2025-11-15T03:05:44Z
publishDate 2021
publisher IAES
recordtype eprints
repository_type Digital Repository
spelling ump-322642022-01-10T00:55:56Z http://umpir.ump.edu.my/id/eprint/32264/ Sigmoid PID based adaptive safe experimentation dynamics algorithm of portable duodopa pump for Parkinson’s disease patients Najwa Hidayah, Abdul Razak Ramesh Mohd Riduwan, Ghazali Mohd Ashraf, Ahmad TK Electrical engineering. Electronics Nuclear engineering This paper emphasizes on the development of an appropriate closed-loop control strategy for traditional portable duodopa pump (PDP); thereby ensuring an automated drug infusion without wearing off. In particular, a sigmoid proportional integral derivative (SPID) controller is adopted to control the blood plasma level of dopamine. The parameters of SPID controller are tuned using the adaptive safe experimentation dynamics (ASED) algorithm. The efficiency of the suggested SPID-ASED is evaluated by concerning the convergence plot of the cost function, the amount of dopamine in the blood plasma (BP) of the patient, the statistical analysis of cost function, norm of error and norm of input, and time responses specifications. The simulation results show that the proposed SPID-ASED outperforms the standard PID controller in terms of better control accuracy with minimum overshoot and settling time. IAES 2021-04 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/32264/1/Sigmoid%20PID%20based%20adaptive%20safe%20experimentation%20dynamics%20algorithm.pdf Najwa Hidayah, Abdul Razak Ramesh and Mohd Riduwan, Ghazali and Mohd Ashraf, Ahmad (2021) Sigmoid PID based adaptive safe experimentation dynamics algorithm of portable duodopa pump for Parkinson’s disease patients. Bulletin of Electrical Engineering and Informatics, 10 (2). 632 -639. ISSN 2089-3191 (Print); 2302-9285 (Online). (Published) https://doi.org/10.11591/eei.v10i2.2542 https://doi.org/10.11591/eei.v10i2.2542
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Najwa Hidayah, Abdul Razak Ramesh
Mohd Riduwan, Ghazali
Mohd Ashraf, Ahmad
Sigmoid PID based adaptive safe experimentation dynamics algorithm of portable duodopa pump for Parkinson’s disease patients
title Sigmoid PID based adaptive safe experimentation dynamics algorithm of portable duodopa pump for Parkinson’s disease patients
title_full Sigmoid PID based adaptive safe experimentation dynamics algorithm of portable duodopa pump for Parkinson’s disease patients
title_fullStr Sigmoid PID based adaptive safe experimentation dynamics algorithm of portable duodopa pump for Parkinson’s disease patients
title_full_unstemmed Sigmoid PID based adaptive safe experimentation dynamics algorithm of portable duodopa pump for Parkinson’s disease patients
title_short Sigmoid PID based adaptive safe experimentation dynamics algorithm of portable duodopa pump for Parkinson’s disease patients
title_sort sigmoid pid based adaptive safe experimentation dynamics algorithm of portable duodopa pump for parkinson’s disease patients
topic TK Electrical engineering. Electronics Nuclear engineering
url http://umpir.ump.edu.my/id/eprint/32264/
http://umpir.ump.edu.my/id/eprint/32264/
http://umpir.ump.edu.my/id/eprint/32264/
http://umpir.ump.edu.my/id/eprint/32264/1/Sigmoid%20PID%20based%20adaptive%20safe%20experimentation%20dynamics%20algorithm.pdf