Medicinal plants with anti-leukemic effects: A review
Leukemia is a leukocyte cancer that is characterized by anarchic growth of immature immune cells in the bone marrow, blood and spleen. There are many forms of leukemia, and the best course of therapy and the chance of a patient’s survival depend on the type of leukemic disease. Different forms of dr...
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| Format: | Article |
| Language: | English |
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MDPI - Open Access Publishing
2021
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| Online Access: | http://umpir.ump.edu.my/id/eprint/31834/ http://umpir.ump.edu.my/id/eprint/31834/1/Medicinal%20plants%20with%20anti-leukemic%20effects.pdf |
| _version_ | 1848823868685287424 |
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| author | Maher, Tahani Raha, Ahmad Raus Daddiouaissa, Djabir Farah, Ahmad Noor Suhana, Adzahar Elda Surhaida, Latif Abdulhafiz, Ferid Mohammed, Arifullah |
| author_facet | Maher, Tahani Raha, Ahmad Raus Daddiouaissa, Djabir Farah, Ahmad Noor Suhana, Adzahar Elda Surhaida, Latif Abdulhafiz, Ferid Mohammed, Arifullah |
| author_sort | Maher, Tahani |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Leukemia is a leukocyte cancer that is characterized by anarchic growth of immature immune cells in the bone marrow, blood and spleen. There are many forms of leukemia, and the best course of therapy and the chance of a patient’s survival depend on the type of leukemic disease. Different forms of drugs have been used to treat leukemia. Due to the adverse effects associated with such therapies and drug resistance, the search for safer and more effective drugs remains one of the most challenging areas of research. Thus, new therapeutic approaches are important to improving outcomes. Almost half of the drugs utilized nowadays in treating cancer are from natural products and their derivatives. Medicinal plants have proven to be an effective natural source of anti-leukemic drugs. The cytotoxicity and the mechanisms underlying the toxicity of these plants to leukemic cells and their isolated compounds were investigated. Effort has been made throughout this comprehensive review to highlight the recent developments and milestones achieved in leukemia therapies using plant-derived compounds and the crude extracts from various medicinal plants. Furthermore, the mechanisms of action of these plants are discussed. |
| first_indexed | 2025-11-15T03:03:59Z |
| format | Article |
| id | ump-31834 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T03:03:59Z |
| publishDate | 2021 |
| publisher | MDPI - Open Access Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-318342021-08-20T08:09:25Z http://umpir.ump.edu.my/id/eprint/31834/ Medicinal plants with anti-leukemic effects: A review Maher, Tahani Raha, Ahmad Raus Daddiouaissa, Djabir Farah, Ahmad Noor Suhana, Adzahar Elda Surhaida, Latif Abdulhafiz, Ferid Mohammed, Arifullah R Medicine (General) RM Therapeutics. Pharmacology TP Chemical technology Leukemia is a leukocyte cancer that is characterized by anarchic growth of immature immune cells in the bone marrow, blood and spleen. There are many forms of leukemia, and the best course of therapy and the chance of a patient’s survival depend on the type of leukemic disease. Different forms of drugs have been used to treat leukemia. Due to the adverse effects associated with such therapies and drug resistance, the search for safer and more effective drugs remains one of the most challenging areas of research. Thus, new therapeutic approaches are important to improving outcomes. Almost half of the drugs utilized nowadays in treating cancer are from natural products and their derivatives. Medicinal plants have proven to be an effective natural source of anti-leukemic drugs. The cytotoxicity and the mechanisms underlying the toxicity of these plants to leukemic cells and their isolated compounds were investigated. Effort has been made throughout this comprehensive review to highlight the recent developments and milestones achieved in leukemia therapies using plant-derived compounds and the crude extracts from various medicinal plants. Furthermore, the mechanisms of action of these plants are discussed. MDPI - Open Access Publishing 2021-05-07 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/31834/1/Medicinal%20plants%20with%20anti-leukemic%20effects.pdf Maher, Tahani and Raha, Ahmad Raus and Daddiouaissa, Djabir and Farah, Ahmad and Noor Suhana, Adzahar and Elda Surhaida, Latif and Abdulhafiz, Ferid and Mohammed, Arifullah (2021) Medicinal plants with anti-leukemic effects: A review. Molecules, 26 (9). pp. 1-25. ISSN 1420-3049 (print); 1420-3049 (online). (Published) https://doi.org/10.3390/molecules26092741 https://doi.org/10.3390/molecules26092741 |
| spellingShingle | R Medicine (General) RM Therapeutics. Pharmacology TP Chemical technology Maher, Tahani Raha, Ahmad Raus Daddiouaissa, Djabir Farah, Ahmad Noor Suhana, Adzahar Elda Surhaida, Latif Abdulhafiz, Ferid Mohammed, Arifullah Medicinal plants with anti-leukemic effects: A review |
| title | Medicinal plants with anti-leukemic effects: A review |
| title_full | Medicinal plants with anti-leukemic effects: A review |
| title_fullStr | Medicinal plants with anti-leukemic effects: A review |
| title_full_unstemmed | Medicinal plants with anti-leukemic effects: A review |
| title_short | Medicinal plants with anti-leukemic effects: A review |
| title_sort | medicinal plants with anti-leukemic effects: a review |
| topic | R Medicine (General) RM Therapeutics. Pharmacology TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/31834/ http://umpir.ump.edu.my/id/eprint/31834/ http://umpir.ump.edu.my/id/eprint/31834/ http://umpir.ump.edu.my/id/eprint/31834/1/Medicinal%20plants%20with%20anti-leukemic%20effects.pdf |