Physicochemical characterization, molecular docking, and in vitro dissolution of glimepiride–captisol inclusion complexes

Physicochemical characterization, molecular docking, and in vitro dissolution of glimepiride–captisol inclusion complexes

This present study investigated the effect of Captisol, a chemically modified cyclodextrin, on the in vitro dissolution of glimepiride. We prepared glimepiride–Captisol complexes of different mass ratios (1:1, 1:2, and 1:3 w/w) by a physical mixing or freeze-drying technique, and found that complexa...

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Bibliographic Details
Main Authors: Pal, Arpita, Roy, Sudeep, Kumar, Akhil, Mahmood, Syed, Nasrin, Khodapanah, Thomas, Sabu, Agatemor, Christian, Ghosal, Kajal
Format: Article
Language:English
Published: American Chemical Society 2020
Subjects:
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/31392/
http://umpir.ump.edu.my/id/eprint/31392/1/Physicochemical%20characterization%20molecular%20docking%2C%20and%20in%20vitro%20dissolution.pdf

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