Optimization of total phenolic compounds extracted from propolis by ultrasound- assisted extraction

The presence of phenolics in propolis contributes to several health benefits such as anti-microbial, antioxidant, anticancer, and anti-inflammatory properties. In this study, total phenolic compounds from propolis were extracted with the aid of sonication. The parameters screening was done by one fa...

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Main Authors: Najihah, Yusof, Mimi Sakinah, A. M., Kutty, R. Veloo
Format: Article
Published: Taylor & Francis 2020
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/30579/
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author Najihah, Yusof
Mimi Sakinah, A. M.
Kutty, R. Veloo
author_facet Najihah, Yusof
Mimi Sakinah, A. M.
Kutty, R. Veloo
author_sort Najihah, Yusof
building UMP Institutional Repository
collection Online Access
description The presence of phenolics in propolis contributes to several health benefits such as anti-microbial, antioxidant, anticancer, and anti-inflammatory properties. In this study, total phenolic compounds from propolis were extracted with the aid of sonication. The parameters screening was done by one factor at time (OFAT) which involved types of solvent, ethanol concentration, extraction temperature and extraction time. The highest total phenolic content obtained was at 80%, 25 minutes, 65 °C for ethanol concentration, extraction time and extraction temperature respectively. Optimization of the experimental parameters was done by applying response surface methodology (RSM). The best potential variation of the factors (X); ethanol concentration (X1), extraction temperature (X2) and extraction time (X3) was generated. The optimum conditions of the variables were 80% (X1), 25 min (X2) and 60 °C (X3). Under this setting, the phenolic content from the experimental work obtained was 0.1007 mg GAE/g of propolis, which complemented the predicted value.
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institution Universiti Malaysia Pahang
institution_category Local University
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publishDate 2020
publisher Taylor & Francis
recordtype eprints
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spelling ump-305792021-01-26T08:18:49Z http://umpir.ump.edu.my/id/eprint/30579/ Optimization of total phenolic compounds extracted from propolis by ultrasound- assisted extraction Najihah, Yusof Mimi Sakinah, A. M. Kutty, R. Veloo TP Chemical technology The presence of phenolics in propolis contributes to several health benefits such as anti-microbial, antioxidant, anticancer, and anti-inflammatory properties. In this study, total phenolic compounds from propolis were extracted with the aid of sonication. The parameters screening was done by one factor at time (OFAT) which involved types of solvent, ethanol concentration, extraction temperature and extraction time. The highest total phenolic content obtained was at 80%, 25 minutes, 65 °C for ethanol concentration, extraction time and extraction temperature respectively. Optimization of the experimental parameters was done by applying response surface methodology (RSM). The best potential variation of the factors (X); ethanol concentration (X1), extraction temperature (X2) and extraction time (X3) was generated. The optimum conditions of the variables were 80% (X1), 25 min (X2) and 60 °C (X3). Under this setting, the phenolic content from the experimental work obtained was 0.1007 mg GAE/g of propolis, which complemented the predicted value. Taylor & Francis 2020 Article PeerReviewed Najihah, Yusof and Mimi Sakinah, A. M. and Kutty, R. Veloo (2020) Optimization of total phenolic compounds extracted from propolis by ultrasound- assisted extraction. Chemical Engineering Communications. pp. 1-10. ISSN 1563-5201. (In Press / Online First) (In Press / Online First) https://doi.org/10.1080/00986445.2020.1761799 https://doi.org/10.1080/00986445.2020.1761799
spellingShingle TP Chemical technology
Najihah, Yusof
Mimi Sakinah, A. M.
Kutty, R. Veloo
Optimization of total phenolic compounds extracted from propolis by ultrasound- assisted extraction
title Optimization of total phenolic compounds extracted from propolis by ultrasound- assisted extraction
title_full Optimization of total phenolic compounds extracted from propolis by ultrasound- assisted extraction
title_fullStr Optimization of total phenolic compounds extracted from propolis by ultrasound- assisted extraction
title_full_unstemmed Optimization of total phenolic compounds extracted from propolis by ultrasound- assisted extraction
title_short Optimization of total phenolic compounds extracted from propolis by ultrasound- assisted extraction
title_sort optimization of total phenolic compounds extracted from propolis by ultrasound- assisted extraction
topic TP Chemical technology
url http://umpir.ump.edu.my/id/eprint/30579/
http://umpir.ump.edu.my/id/eprint/30579/
http://umpir.ump.edu.my/id/eprint/30579/