Design and optimization of a probiotic tablet for gastrointestinal tolerance by a simplex-centroid mixture.

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Design and optimization of a probiotic tablet for gastrointestinal tolerance by a simplex-centroid mixture.

In this study, a simplex-centroid mixture design using design of experiment (DOE) software was implemented to evaluate the effect of biopolymers as excipients, which are hydroxypropyl methylcellulose, and alginate, on the gastrointestinal tolerance of probiotic tablet containing Saccharomyces boular...

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Bibliographic Details
Main Authors:	Mohd Akmal, Azhar, Mimi Sakinah, Abdul Munaim
Format:	Article
Language:	English
Published:	Taylor & Francis 2020
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/30455/ http://umpir.ump.edu.my/id/eprint/30455/1/azhar2020.pdf

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