Convergent synthesis of new N -substituted 2-{[5-(1H -indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl} acetamides as suitable therapeutic agents

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Convergent synthesis of new N -substituted 2-{[5-(1H -indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl} acetamides as suitable therapeutic agents

A series of N-substituted 2-{[5-(1H-indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl} acetamides (8a-w) was synthesized in three steps. The first step involved the sequential conversion of 2-(1H-indol-3-yl) acetic acid (1) to ester (2) followed by hydrazide (3) formation and finally cyclization in th...

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Bibliographic Details
Main Authors:	Rubab, Kaniz, Abbasi, Muhammad Athar, Ur-Rehman, Aziz, Siddiqui, Sabahat Zahra, Ashraf, Muhammad, Shaukat, Ayesha, Ahmad, Irshad, Lodhi, Muhammad A., Khan, Farman Ali, Shahid, Muhammad, Akhtar, Muhammad Nadeem
Format:	Article
Language:	English
Published:	Faculdade de Ciencias Farmaceuticas (Biblioteca) 2015
Subjects:	QD Chemistry TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/29801/ http://umpir.ump.edu.my/id/eprint/29801/1/Convergent%20synthesis%20of%20new%20N%20-substituted%202.pdf

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