Detection of colon cancer based on microarray dataset using machine learning as a feature selection and classification techniques

Microarray data is an increasingly important tool for providing information on gene expression for analysis and interpretation. Researchers attempt to utilize the smallest possible set of relevant gene expression profiles in most gene expression studies to enhance tumor identification accuracy. This...

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Main Authors: A. S. M, Shafi, M. M., Imran Molla, Jui, Julakha Jahan, Mohammad, Motiur Rahman
Format: Article
Language:English
Published: Springer Link 2020
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/28914/
http://umpir.ump.edu.my/id/eprint/28914/1/Shafi2020_Article_DetectionOfColonCancerBasedOnM.pdf
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author A. S. M, Shafi
M. M., Imran Molla
Jui, Julakha Jahan
Mohammad, Motiur Rahman
author_facet A. S. M, Shafi
M. M., Imran Molla
Jui, Julakha Jahan
Mohammad, Motiur Rahman
author_sort A. S. M, Shafi
building UMP Institutional Repository
collection Online Access
description Microarray data is an increasingly important tool for providing information on gene expression for analysis and interpretation. Researchers attempt to utilize the smallest possible set of relevant gene expression profiles in most gene expression studies to enhance tumor identification accuracy. This research aims to analyze and predicts colon cancer data employing a machine learning approach and feature selection technique based on a random forest classifier. More particularly, our proposed method can reduce the burden of high dimensional data and allow faster calculations by combining the “Mean Decrease Accuracy” and “Mean Decrease Gini” as feature selection methods into a renowned classifier namely Random Forest, with the aim of increasing the prediction model's accuracy level. In addition, we have also shown a comparative model analysis with selection of features and model without selection of features. The extensive experimental results have demonstrated that the proposed model with feature selection is favorable and effective which triumphs the best performance of accuracy.
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institution Universiti Malaysia Pahang
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publishDate 2020
publisher Springer Link
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spelling ump-289142020-07-29T05:10:09Z http://umpir.ump.edu.my/id/eprint/28914/ Detection of colon cancer based on microarray dataset using machine learning as a feature selection and classification techniques A. S. M, Shafi M. M., Imran Molla Jui, Julakha Jahan Mohammad, Motiur Rahman QA76 Computer software Microarray data is an increasingly important tool for providing information on gene expression for analysis and interpretation. Researchers attempt to utilize the smallest possible set of relevant gene expression profiles in most gene expression studies to enhance tumor identification accuracy. This research aims to analyze and predicts colon cancer data employing a machine learning approach and feature selection technique based on a random forest classifier. More particularly, our proposed method can reduce the burden of high dimensional data and allow faster calculations by combining the “Mean Decrease Accuracy” and “Mean Decrease Gini” as feature selection methods into a renowned classifier namely Random Forest, with the aim of increasing the prediction model's accuracy level. In addition, we have also shown a comparative model analysis with selection of features and model without selection of features. The extensive experimental results have demonstrated that the proposed model with feature selection is favorable and effective which triumphs the best performance of accuracy. Springer Link 2020-06-18 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/28914/1/Shafi2020_Article_DetectionOfColonCancerBasedOnM.pdf A. S. M, Shafi and M. M., Imran Molla and Jui, Julakha Jahan and Mohammad, Motiur Rahman (2020) Detection of colon cancer based on microarray dataset using machine learning as a feature selection and classification techniques. Engineering: Application of Machine Learning in Engineering (1243). (Published) https://doi.org/10.1007/s42452-020-3051-2
spellingShingle QA76 Computer software
A. S. M, Shafi
M. M., Imran Molla
Jui, Julakha Jahan
Mohammad, Motiur Rahman
Detection of colon cancer based on microarray dataset using machine learning as a feature selection and classification techniques
title Detection of colon cancer based on microarray dataset using machine learning as a feature selection and classification techniques
title_full Detection of colon cancer based on microarray dataset using machine learning as a feature selection and classification techniques
title_fullStr Detection of colon cancer based on microarray dataset using machine learning as a feature selection and classification techniques
title_full_unstemmed Detection of colon cancer based on microarray dataset using machine learning as a feature selection and classification techniques
title_short Detection of colon cancer based on microarray dataset using machine learning as a feature selection and classification techniques
title_sort detection of colon cancer based on microarray dataset using machine learning as a feature selection and classification techniques
topic QA76 Computer software
url http://umpir.ump.edu.my/id/eprint/28914/
http://umpir.ump.edu.my/id/eprint/28914/
http://umpir.ump.edu.my/id/eprint/28914/1/Shafi2020_Article_DetectionOfColonCancerBasedOnM.pdf