Mass spectrometry analysis of auxiliary energy-induced terpenes extraction from Andrographis Paniculata
The auxiliary energy level affects the yield of terpene extraction from Andrographis paniculata. This paper presents the effect of auxiliary energy (0.22–50 W/mL) to the extraction yield of terpenes from Andrographis paniculata for the first time. Ultra-performance liquid chromatography-quadrupole t...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Published: |
Elsevier Ltd
2020
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/28902/ |
| _version_ | 1848823163467595776 |
|---|---|
| author | Chia, Vi Vien Pang, Sook Fun Jolius, Gimbun |
| author_facet | Chia, Vi Vien Pang, Sook Fun Jolius, Gimbun |
| author_sort | Chia, Vi Vien |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | The auxiliary energy level affects the yield of terpene extraction from Andrographis paniculata. This paper presents the effect of auxiliary energy (0.22–50 W/mL) to the extraction yield of terpenes from Andrographis paniculata for the first time. Ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS) method was developed for qualitative and quantitative analysis of terpene. It was found that, the highest yield of andrographolide (20.10 mg g/DW) and neoandrographolide (9.54 mg g/DW) was produced at a relatively lower level of auxiliary energy (1.34 W/mL). Meanwhile the highest yield of 14-deoxy-11,12-didehydroandrographolide (6.47 mg g/DW) was obtained at a higher level of auxiliary energy (25 W/mL), which indicates the existence of a thermally-induced extractive-synthesis mechanism. Principal component analyses on the mass spectra confirmed maceration, ultrasonic, and microwave assisted extraction differ appreciably and eight compounds contributing to the differences were successfully elucidated. |
| first_indexed | 2025-11-15T02:52:46Z |
| format | Article |
| id | ump-28902 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| last_indexed | 2025-11-15T02:52:46Z |
| publishDate | 2020 |
| publisher | Elsevier Ltd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-289022021-04-22T06:48:33Z http://umpir.ump.edu.my/id/eprint/28902/ Mass spectrometry analysis of auxiliary energy-induced terpenes extraction from Andrographis Paniculata Chia, Vi Vien Pang, Sook Fun Jolius, Gimbun TP Chemical technology The auxiliary energy level affects the yield of terpene extraction from Andrographis paniculata. This paper presents the effect of auxiliary energy (0.22–50 W/mL) to the extraction yield of terpenes from Andrographis paniculata for the first time. Ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS) method was developed for qualitative and quantitative analysis of terpene. It was found that, the highest yield of andrographolide (20.10 mg g/DW) and neoandrographolide (9.54 mg g/DW) was produced at a relatively lower level of auxiliary energy (1.34 W/mL). Meanwhile the highest yield of 14-deoxy-11,12-didehydroandrographolide (6.47 mg g/DW) was obtained at a higher level of auxiliary energy (25 W/mL), which indicates the existence of a thermally-induced extractive-synthesis mechanism. Principal component analyses on the mass spectra confirmed maceration, ultrasonic, and microwave assisted extraction differ appreciably and eight compounds contributing to the differences were successfully elucidated. Elsevier Ltd 2020-07-28 Article PeerReviewed Chia, Vi Vien and Pang, Sook Fun and Jolius, Gimbun (2020) Mass spectrometry analysis of auxiliary energy-induced terpenes extraction from Andrographis Paniculata. Industrial Crops and Products, 155 (112828). pp. 1-7. ISSN 0926-6690. (Published) https://doi.org/10.1016/j.indcrop.2020.112828 https://doi.org/10.1016/j.indcrop.2020.112828 |
| spellingShingle | TP Chemical technology Chia, Vi Vien Pang, Sook Fun Jolius, Gimbun Mass spectrometry analysis of auxiliary energy-induced terpenes extraction from Andrographis Paniculata |
| title | Mass spectrometry analysis of auxiliary energy-induced terpenes extraction from Andrographis Paniculata |
| title_full | Mass spectrometry analysis of auxiliary energy-induced terpenes extraction from Andrographis Paniculata |
| title_fullStr | Mass spectrometry analysis of auxiliary energy-induced terpenes extraction from Andrographis Paniculata |
| title_full_unstemmed | Mass spectrometry analysis of auxiliary energy-induced terpenes extraction from Andrographis Paniculata |
| title_short | Mass spectrometry analysis of auxiliary energy-induced terpenes extraction from Andrographis Paniculata |
| title_sort | mass spectrometry analysis of auxiliary energy-induced terpenes extraction from andrographis paniculata |
| topic | TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/28902/ http://umpir.ump.edu.my/id/eprint/28902/ http://umpir.ump.edu.my/id/eprint/28902/ |