Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on physicochemical properties

Plant derived substances and herbal medicines have recently attracted the great interest towards their versatile application, as medicinal plants used in traditional and modern medicine. The aim of the current study was to investigate the antioxidant activity of Ziziphus mauritiana leaves extract fo...

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Main Authors: Siti Umairah, Mokhtar, Ashviny, Murugan, Che Syahira, Che Awang
Format: Article
Language:English
Published: Penerbit Universiti Malaysia Pahang 2020
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/28462/
http://umpir.ump.edu.my/id/eprint/28462/1/Formulation%20of%20herbal%20cream%20based%20on%20Ziziphus%20Mauritiana.pdf
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author Siti Umairah, Mokhtar
Ashviny, Murugan
Che Syahira, Che Awang
author_facet Siti Umairah, Mokhtar
Ashviny, Murugan
Che Syahira, Che Awang
author_sort Siti Umairah, Mokhtar
building UMP Institutional Repository
collection Online Access
description Plant derived substances and herbal medicines have recently attracted the great interest towards their versatile application, as medicinal plants used in traditional and modern medicine. The aim of the current study was to investigate the antioxidant activity of Ziziphus mauritiana leaves extract followed with the formulation of herbal creams based on ZM methanolic extract then evaluate the physical characteristic and stability of the creams. After the methanolic extract was obtained by using Soxhlet extraction, the extract was assessed for antioxidant activity by using stable 2,2- Diphenyl-1-picrylhydrazyl (DPPH) which showed the IC50 value of the ZM extract is 10.57 µg/ml, while IC50 value for ascorbic acid is 4.19 µg/ml. Four formulations of water in oil (w/o) emulsion based cream was formulated based on Ziziphus mauritiana leaves extract which are F1, F2, F3 and F4. Several physical properties were evaluated such as organoleptic, pH, viscosity, homogeneity, washability and emmolliency which proved that all formulations have good homogeneity, non greasy and under suitable pH and viscosity. Based on thermal stability test (45 °C ± 70 % RH, for 48 hours), it showed that F4 is not stable at high temperature compared to other formulations. Therefore, the present study indicated that the Ziziphus mauritiana leaves extract has great potential for personal care product development.
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spelling ump-284622022-01-26T05:27:33Z http://umpir.ump.edu.my/id/eprint/28462/ Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on physicochemical properties Siti Umairah, Mokhtar Ashviny, Murugan Che Syahira, Che Awang TP Chemical technology Plant derived substances and herbal medicines have recently attracted the great interest towards their versatile application, as medicinal plants used in traditional and modern medicine. The aim of the current study was to investigate the antioxidant activity of Ziziphus mauritiana leaves extract followed with the formulation of herbal creams based on ZM methanolic extract then evaluate the physical characteristic and stability of the creams. After the methanolic extract was obtained by using Soxhlet extraction, the extract was assessed for antioxidant activity by using stable 2,2- Diphenyl-1-picrylhydrazyl (DPPH) which showed the IC50 value of the ZM extract is 10.57 µg/ml, while IC50 value for ascorbic acid is 4.19 µg/ml. Four formulations of water in oil (w/o) emulsion based cream was formulated based on Ziziphus mauritiana leaves extract which are F1, F2, F3 and F4. Several physical properties were evaluated such as organoleptic, pH, viscosity, homogeneity, washability and emmolliency which proved that all formulations have good homogeneity, non greasy and under suitable pH and viscosity. Based on thermal stability test (45 °C ± 70 % RH, for 48 hours), it showed that F4 is not stable at high temperature compared to other formulations. Therefore, the present study indicated that the Ziziphus mauritiana leaves extract has great potential for personal care product development. Penerbit Universiti Malaysia Pahang 2020-02-28 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/28462/1/Formulation%20of%20herbal%20cream%20based%20on%20Ziziphus%20Mauritiana.pdf Siti Umairah, Mokhtar and Ashviny, Murugan and Che Syahira, Che Awang (2020) Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on physicochemical properties. International Journal of Engineering Technology And Sciences (IJETS), 8 (1). pp. 34-39. ISSN 2289-697X. (Published) https://doi.org/10.15282/ijets.8.1.2021.1005 https://doi.org/10.15282/ijets.8.1.2021.1005
spellingShingle TP Chemical technology
Siti Umairah, Mokhtar
Ashviny, Murugan
Che Syahira, Che Awang
Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on physicochemical properties
title Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on physicochemical properties
title_full Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on physicochemical properties
title_fullStr Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on physicochemical properties
title_full_unstemmed Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on physicochemical properties
title_short Formulation of herbal cream based on Ziziphus Mauritiana leaves extract and evaluation on physicochemical properties
title_sort formulation of herbal cream based on ziziphus mauritiana leaves extract and evaluation on physicochemical properties
topic TP Chemical technology
url http://umpir.ump.edu.my/id/eprint/28462/
http://umpir.ump.edu.my/id/eprint/28462/
http://umpir.ump.edu.my/id/eprint/28462/
http://umpir.ump.edu.my/id/eprint/28462/1/Formulation%20of%20herbal%20cream%20based%20on%20Ziziphus%20Mauritiana.pdf