Synthesis of silver nanoparticles by clinacanthus nutans extract supported with identification of flavonoids by UPLC-QTOF/MS and its antimicrobial activity

The present study reported a simple method in synthesizing silver nanoparticles (AgNPs) by using Clinacanthus nutans extract. The UV–visible spectra showed the characteristic absorption peak at 480 nm, and the intensity was increased with the increase in plant extract ratio and incubation period. An...

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Main Authors: Hazrulrizawati, Hamid, Roziasyahira, Mutazah
Format: Article
Language:English
Published: Springer 2019
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/26793/
http://umpir.ump.edu.my/id/eprint/26793/1/Synthesis%20of%20silver%20nanoparticles%20by%20clinacanthus%20nutans%20extract%20.pdf
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author Hazrulrizawati, Hamid
Roziasyahira, Mutazah
author_facet Hazrulrizawati, Hamid
Roziasyahira, Mutazah
author_sort Hazrulrizawati, Hamid
building UMP Institutional Repository
collection Online Access
description The present study reported a simple method in synthesizing silver nanoparticles (AgNPs) by using Clinacanthus nutans extract. The UV–visible spectra showed the characteristic absorption peak at 480 nm, and the intensity was increased with the increase in plant extract ratio and incubation period. Analysis of particle size through FESEM, XRD and TEM revealed the average of synthesized AgNPs is 73.4 nm. The EDX analysis confirmed the formation of metallic nature of silver. The FTIR spectra indicated the role of carbonyl groups in the synthetic process and further confirmed by identification of flavonoids and their glycosides by UPLC-QTOF/MS. Antimicrobial activity of biosynthesized AgNPs shows effective inhibition against common bacterial strains including Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Proteus vulgaris.
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publishDate 2019
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spelling ump-267932020-03-12T07:01:34Z http://umpir.ump.edu.my/id/eprint/26793/ Synthesis of silver nanoparticles by clinacanthus nutans extract supported with identification of flavonoids by UPLC-QTOF/MS and its antimicrobial activity Hazrulrizawati, Hamid Roziasyahira, Mutazah TP Chemical technology The present study reported a simple method in synthesizing silver nanoparticles (AgNPs) by using Clinacanthus nutans extract. The UV–visible spectra showed the characteristic absorption peak at 480 nm, and the intensity was increased with the increase in plant extract ratio and incubation period. Analysis of particle size through FESEM, XRD and TEM revealed the average of synthesized AgNPs is 73.4 nm. The EDX analysis confirmed the formation of metallic nature of silver. The FTIR spectra indicated the role of carbonyl groups in the synthetic process and further confirmed by identification of flavonoids and their glycosides by UPLC-QTOF/MS. Antimicrobial activity of biosynthesized AgNPs shows effective inhibition against common bacterial strains including Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Proteus vulgaris. Springer 2019-10-01 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/26793/1/Synthesis%20of%20silver%20nanoparticles%20by%20clinacanthus%20nutans%20extract%20.pdf Hazrulrizawati, Hamid and Roziasyahira, Mutazah (2019) Synthesis of silver nanoparticles by clinacanthus nutans extract supported with identification of flavonoids by UPLC-QTOF/MS and its antimicrobial activity. Iranian Journal of Science and Technology, Transaction A: Science, 43 (5). pp. 2219-2225. ISSN 1028-6276. (Published) https://doi.org/10.1007/s40995-018-0659-9 https://doi.org/10.1007/s40995-018-0659-9
spellingShingle TP Chemical technology
Hazrulrizawati, Hamid
Roziasyahira, Mutazah
Synthesis of silver nanoparticles by clinacanthus nutans extract supported with identification of flavonoids by UPLC-QTOF/MS and its antimicrobial activity
title Synthesis of silver nanoparticles by clinacanthus nutans extract supported with identification of flavonoids by UPLC-QTOF/MS and its antimicrobial activity
title_full Synthesis of silver nanoparticles by clinacanthus nutans extract supported with identification of flavonoids by UPLC-QTOF/MS and its antimicrobial activity
title_fullStr Synthesis of silver nanoparticles by clinacanthus nutans extract supported with identification of flavonoids by UPLC-QTOF/MS and its antimicrobial activity
title_full_unstemmed Synthesis of silver nanoparticles by clinacanthus nutans extract supported with identification of flavonoids by UPLC-QTOF/MS and its antimicrobial activity
title_short Synthesis of silver nanoparticles by clinacanthus nutans extract supported with identification of flavonoids by UPLC-QTOF/MS and its antimicrobial activity
title_sort synthesis of silver nanoparticles by clinacanthus nutans extract supported with identification of flavonoids by uplc-qtof/ms and its antimicrobial activity
topic TP Chemical technology
url http://umpir.ump.edu.my/id/eprint/26793/
http://umpir.ump.edu.my/id/eprint/26793/
http://umpir.ump.edu.my/id/eprint/26793/
http://umpir.ump.edu.my/id/eprint/26793/1/Synthesis%20of%20silver%20nanoparticles%20by%20clinacanthus%20nutans%20extract%20.pdf