Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion
One of the risks of ischaemic stroke reperfusion treatment is the formation of brain oedema. This is usually observed clinically by the formation of herniation, which if not treated, it may disrupt brain functionality. In this paper, a mathematical model of brain oedema formation after stroke has be...
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| Format: | Conference or Workshop Item |
| Language: | English |
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Universiti Malaysia Pahang
2019
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| Online Access: | http://umpir.ump.edu.my/id/eprint/26052/ http://umpir.ump.edu.my/id/eprint/26052/1/62.%20Finite%20element%20poroelastic%20modelling%20of%20brain%20oedema.pdf |
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| author | Mohd Jamil Mohamed, Mokhtarudin Aina Najwa, Nadzri Stephen, Payne |
| author_facet | Mohd Jamil Mohamed, Mokhtarudin Aina Najwa, Nadzri Stephen, Payne |
| author_sort | Mohd Jamil Mohamed, Mokhtarudin |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | One of the risks of ischaemic stroke reperfusion treatment is the formation of brain oedema. This is usually observed clinically by the formation of herniation, which if not treated, it may disrupt brain functionality. In this paper, a mathematical model of brain oedema formation after stroke has been developed and simulated on an ideal 3D brain geometry with different infarct sizes and locations, to see their effects on brain herniation. The brain tissue displacement and pressure are then analyzed. It is found that those infarcts with large sizes and located nearer to the brain ventricle cause severe brain herniation. |
| first_indexed | 2025-11-15T02:41:10Z |
| format | Conference or Workshop Item |
| id | ump-26052 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T02:41:10Z |
| publishDate | 2019 |
| publisher | Universiti Malaysia Pahang |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-260522019-12-20T07:15:26Z http://umpir.ump.edu.my/id/eprint/26052/ Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion Mohd Jamil Mohamed, Mokhtarudin Aina Najwa, Nadzri Stephen, Payne TJ Mechanical engineering and machinery One of the risks of ischaemic stroke reperfusion treatment is the formation of brain oedema. This is usually observed clinically by the formation of herniation, which if not treated, it may disrupt brain functionality. In this paper, a mathematical model of brain oedema formation after stroke has been developed and simulated on an ideal 3D brain geometry with different infarct sizes and locations, to see their effects on brain herniation. The brain tissue displacement and pressure are then analyzed. It is found that those infarcts with large sizes and located nearer to the brain ventricle cause severe brain herniation. Universiti Malaysia Pahang 2019 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/26052/1/62.%20Finite%20element%20poroelastic%20modelling%20of%20brain%20oedema.pdf Mohd Jamil Mohamed, Mokhtarudin and Aina Najwa, Nadzri and Stephen, Payne (2019) Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion. In: 6th International Conference on Computational and Mathematical Biomedical Engineering (CMBE 2019) , 10-12 June 2019 , Japan. pp. 1-4.. (Published) |
| spellingShingle | TJ Mechanical engineering and machinery Mohd Jamil Mohamed, Mokhtarudin Aina Najwa, Nadzri Stephen, Payne Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion |
| title | Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion |
| title_full | Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion |
| title_fullStr | Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion |
| title_full_unstemmed | Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion |
| title_short | Finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion |
| title_sort | finite element poroelastic modelling of brain oedema formation after ischaemic stroke reperfusion |
| topic | TJ Mechanical engineering and machinery |
| url | http://umpir.ump.edu.my/id/eprint/26052/ http://umpir.ump.edu.my/id/eprint/26052/1/62.%20Finite%20element%20poroelastic%20modelling%20of%20brain%20oedema.pdf |