Investigation of the capillary effects toward brain tissue poroelastic properties using asymptotic expansion homogenization
Existing brain model to study brain oedema formation has an assumption of homogeneous brain capillary distribution, despite it is actually normally distributed. In this paper, the assumption is improved by applying asymptotic expansion homogenization (AEH) to a vascularized poroelastic model to obta...
| Main Authors: | , , , |
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| Format: | Conference or Workshop Item |
| Language: | English English |
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Universiti Malaysia Pahang
2019
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/26044/ http://umpir.ump.edu.my/id/eprint/26044/1/61.%20Investigation%20of%20the%20capillary%20effects%20toward%20brain%20tissue.pdf http://umpir.ump.edu.my/id/eprint/26044/2/61.1%20Investigation%20of%20the%20capillary%20effects%20toward%20brain%20tissue.pdf |
| _version_ | 1848822431835226112 |
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| author | Abbas, Shabudin Mohd Jamil Mohamed, Mokhtarudin Payne, Stephen J. Nik Abdullah, Nik Mohamed |
| author_facet | Abbas, Shabudin Mohd Jamil Mohamed, Mokhtarudin Payne, Stephen J. Nik Abdullah, Nik Mohamed |
| author_sort | Abbas, Shabudin |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Existing brain model to study brain oedema formation has an assumption of homogeneous brain capillary distribution, despite it is actually normally distributed. In this paper, the assumption is improved by applying asymptotic expansion homogenization (AEH) to a vascularized poroelastic model to obtain a new homogenized macroscale governing equations with 4 microscale cell problems. The cell problems are solved on a cube of brain tissue with capillary to obtain 4 tensors describing the mechanical and fluid transport properties of the brain. From the simulations, only the blood permeability and Biot’s parameter tensors are significantly affected by the capillary tortuosities. |
| first_indexed | 2025-11-15T02:41:08Z |
| format | Conference or Workshop Item |
| id | ump-26044 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T02:41:08Z |
| publishDate | 2019 |
| publisher | Universiti Malaysia Pahang |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-260442019-12-17T04:27:17Z http://umpir.ump.edu.my/id/eprint/26044/ Investigation of the capillary effects toward brain tissue poroelastic properties using asymptotic expansion homogenization Abbas, Shabudin Mohd Jamil Mohamed, Mokhtarudin Payne, Stephen J. Nik Abdullah, Nik Mohamed TJ Mechanical engineering and machinery Existing brain model to study brain oedema formation has an assumption of homogeneous brain capillary distribution, despite it is actually normally distributed. In this paper, the assumption is improved by applying asymptotic expansion homogenization (AEH) to a vascularized poroelastic model to obtain a new homogenized macroscale governing equations with 4 microscale cell problems. The cell problems are solved on a cube of brain tissue with capillary to obtain 4 tensors describing the mechanical and fluid transport properties of the brain. From the simulations, only the blood permeability and Biot’s parameter tensors are significantly affected by the capillary tortuosities. Universiti Malaysia Pahang 2019 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/26044/1/61.%20Investigation%20of%20the%20capillary%20effects%20toward%20brain%20tissue.pdf pdf en http://umpir.ump.edu.my/id/eprint/26044/2/61.1%20Investigation%20of%20the%20capillary%20effects%20toward%20brain%20tissue.pdf Abbas, Shabudin and Mohd Jamil Mohamed, Mokhtarudin and Payne, Stephen J. and Nik Abdullah, Nik Mohamed (2019) Investigation of the capillary effects toward brain tissue poroelastic properties using asymptotic expansion homogenization. In: 6th International Conference on Computational and Mathematical Biomedical Engineering (CMBE 2019) , 10-12 June 2019 , Japan. pp. 1-4.. (Published) |
| spellingShingle | TJ Mechanical engineering and machinery Abbas, Shabudin Mohd Jamil Mohamed, Mokhtarudin Payne, Stephen J. Nik Abdullah, Nik Mohamed Investigation of the capillary effects toward brain tissue poroelastic properties using asymptotic expansion homogenization |
| title | Investigation of the capillary effects toward brain tissue poroelastic properties using asymptotic expansion homogenization |
| title_full | Investigation of the capillary effects toward brain tissue poroelastic properties using asymptotic expansion homogenization |
| title_fullStr | Investigation of the capillary effects toward brain tissue poroelastic properties using asymptotic expansion homogenization |
| title_full_unstemmed | Investigation of the capillary effects toward brain tissue poroelastic properties using asymptotic expansion homogenization |
| title_short | Investigation of the capillary effects toward brain tissue poroelastic properties using asymptotic expansion homogenization |
| title_sort | investigation of the capillary effects toward brain tissue poroelastic properties using asymptotic expansion homogenization |
| topic | TJ Mechanical engineering and machinery |
| url | http://umpir.ump.edu.my/id/eprint/26044/ http://umpir.ump.edu.my/id/eprint/26044/1/61.%20Investigation%20of%20the%20capillary%20effects%20toward%20brain%20tissue.pdf http://umpir.ump.edu.my/id/eprint/26044/2/61.1%20Investigation%20of%20the%20capillary%20effects%20toward%20brain%20tissue.pdf |