Mathematical modeling of cancer growth process: A review

Although cancer is a leading cause of death, a little is known about the mechanism of its growth and destruction. Mathematical models explaining these mechanisms are crucial to predict the behaviour of cancer cells proliferation. Perusal of the literature dealing with mathematical modelling of cance...

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Main Authors: Tabassum, Shabana, Norhayati, Rosli, Mazma Sayahidatul Ayuni, Mazalan
Format: Conference or Workshop Item
Language:English
Published: IOP Publishing 2019
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/25594/
http://umpir.ump.edu.my/id/eprint/25594/1/9.%20Mathematical%20modeling%20of%20cancer%20growth%20process%20-%20a%20review.pdf
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author Tabassum, Shabana
Norhayati, Rosli
Mazma Sayahidatul Ayuni, Mazalan
author_facet Tabassum, Shabana
Norhayati, Rosli
Mazma Sayahidatul Ayuni, Mazalan
author_sort Tabassum, Shabana
building UMP Institutional Repository
collection Online Access
description Although cancer is a leading cause of death, a little is known about the mechanism of its growth and destruction. Mathematical models explaining these mechanisms are crucial to predict the behaviour of cancer cells proliferation. Perusal of the literature dealing with mathematical modelling of cancer initiation, proliferation and metastases is abundant. Mathematical models to simulate the growth rate of the cancer cells have been derived from both deterministic and stochastic considerations. Early model of tumor growth by diffusion was first introduced and then set the scene for many later mathematical models for solid tumors. In this article we review the deterministic and stochastic models that have been developing to discuss the tumor growth initiation and proliferation. The findings and interpretations are summarized, and the main research issues are highlighted
first_indexed 2025-11-15T02:39:20Z
format Conference or Workshop Item
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institution Universiti Malaysia Pahang
institution_category Local University
language English
last_indexed 2025-11-15T02:39:20Z
publishDate 2019
publisher IOP Publishing
recordtype eprints
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spelling ump-255942020-04-13T01:28:40Z http://umpir.ump.edu.my/id/eprint/25594/ Mathematical modeling of cancer growth process: A review Tabassum, Shabana Norhayati, Rosli Mazma Sayahidatul Ayuni, Mazalan TK Electrical engineering. Electronics Nuclear engineering Although cancer is a leading cause of death, a little is known about the mechanism of its growth and destruction. Mathematical models explaining these mechanisms are crucial to predict the behaviour of cancer cells proliferation. Perusal of the literature dealing with mathematical modelling of cancer initiation, proliferation and metastases is abundant. Mathematical models to simulate the growth rate of the cancer cells have been derived from both deterministic and stochastic considerations. Early model of tumor growth by diffusion was first introduced and then set the scene for many later mathematical models for solid tumors. In this article we review the deterministic and stochastic models that have been developing to discuss the tumor growth initiation and proliferation. The findings and interpretations are summarized, and the main research issues are highlighted IOP Publishing 2019 Conference or Workshop Item PeerReviewed pdf en cc_by http://umpir.ump.edu.my/id/eprint/25594/1/9.%20Mathematical%20modeling%20of%20cancer%20growth%20process%20-%20a%20review.pdf Tabassum, Shabana and Norhayati, Rosli and Mazma Sayahidatul Ayuni, Mazalan (2019) Mathematical modeling of cancer growth process: A review. In: Journal of Physics: Conference Series, 2nd International Conference on Applied & Industrial Mathematics and Statistics (ICoAIMS 2019) , 23-25 July 2019 , Kuantan, Pahang, Malaysia. pp. 1-6., 1366 (012018). ISSN 1742-6588 (print); 1742-6596 (online) (Published) https://doi.org/10.1088/1742-6596/1366/1/012018
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Tabassum, Shabana
Norhayati, Rosli
Mazma Sayahidatul Ayuni, Mazalan
Mathematical modeling of cancer growth process: A review
title Mathematical modeling of cancer growth process: A review
title_full Mathematical modeling of cancer growth process: A review
title_fullStr Mathematical modeling of cancer growth process: A review
title_full_unstemmed Mathematical modeling of cancer growth process: A review
title_short Mathematical modeling of cancer growth process: A review
title_sort mathematical modeling of cancer growth process: a review
topic TK Electrical engineering. Electronics Nuclear engineering
url http://umpir.ump.edu.my/id/eprint/25594/
http://umpir.ump.edu.my/id/eprint/25594/
http://umpir.ump.edu.my/id/eprint/25594/1/9.%20Mathematical%20modeling%20of%20cancer%20growth%20process%20-%20a%20review.pdf