Empirical robustness evaluation of DNA-based clustering methods

DNA-based computation is one of the latest computation paradigms. Compared to conventional methods that obtain their end results via electronic processes, aDNA-based approach obtains its result from bio-chemical reactions. It is essential in this approach for all experimental processes to be perform...

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Main Authors: Rohani, Abu Bakar, Watada, Junzo
Format: Article
Language:English
Published: Taylor & Francis 2011
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/25578/
http://umpir.ump.edu.my/id/eprint/25578/1/Empirical%20robustness%20evaluation%20of%20DNA-based%20clustering%20methods.pdf
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author Rohani, Abu Bakar
Watada, Junzo
author_facet Rohani, Abu Bakar
Watada, Junzo
author_sort Rohani, Abu Bakar
building UMP Institutional Repository
collection Online Access
description DNA-based computation is one of the latest computation paradigms. Compared to conventional methods that obtain their end results via electronic processes, aDNA-based approach obtains its result from bio-chemical reactions. It is essential in this approach for all experimental processes to be performed without fault. However, some errors may occur while carrying out these bio-chemical experiments. Consequently, it is necessary to overcome their weaknesses. The aim of this study is to examine the robustness of DNA-based techniques in solving a clustering problem. In the broadest sense, robustness can be defined as being able to withstand stresses, pressures, or changes in procedure or circumstance. To examine the robustness of the approach, this research examined the impact of error or added noise on DNA-based procedure results. Comparative studies of different error sets are also provided here. Additionally, two well-known conventional clustering algorithms (Fuzzy C-means and k-means) were applied to the same error sets, to study the reliability and validity of results when comparing DNA-based clustering.
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spelling ump-255782020-02-11T06:58:42Z http://umpir.ump.edu.my/id/eprint/25578/ Empirical robustness evaluation of DNA-based clustering methods Rohani, Abu Bakar Watada, Junzo QA76 Computer software DNA-based computation is one of the latest computation paradigms. Compared to conventional methods that obtain their end results via electronic processes, aDNA-based approach obtains its result from bio-chemical reactions. It is essential in this approach for all experimental processes to be performed without fault. However, some errors may occur while carrying out these bio-chemical experiments. Consequently, it is necessary to overcome their weaknesses. The aim of this study is to examine the robustness of DNA-based techniques in solving a clustering problem. In the broadest sense, robustness can be defined as being able to withstand stresses, pressures, or changes in procedure or circumstance. To examine the robustness of the approach, this research examined the impact of error or added noise on DNA-based procedure results. Comparative studies of different error sets are also provided here. Additionally, two well-known conventional clustering algorithms (Fuzzy C-means and k-means) were applied to the same error sets, to study the reliability and validity of results when comparing DNA-based clustering. Taylor & Francis 2011 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/25578/1/Empirical%20robustness%20evaluation%20of%20DNA-based%20clustering%20methods.pdf Rohani, Abu Bakar and Watada, Junzo (2011) Empirical robustness evaluation of DNA-based clustering methods. International Journal of Intelligent Computing in Medical Sciences and Image Processing, 4 (1). pp. 1-12. ISSN 1931-308X. (Published) https://doi.org/10.1080/1931308X.2011.10644179 https://doi.org/10.1080/1931308X.2011.10644179
spellingShingle QA76 Computer software
Rohani, Abu Bakar
Watada, Junzo
Empirical robustness evaluation of DNA-based clustering methods
title Empirical robustness evaluation of DNA-based clustering methods
title_full Empirical robustness evaluation of DNA-based clustering methods
title_fullStr Empirical robustness evaluation of DNA-based clustering methods
title_full_unstemmed Empirical robustness evaluation of DNA-based clustering methods
title_short Empirical robustness evaluation of DNA-based clustering methods
title_sort empirical robustness evaluation of dna-based clustering methods
topic QA76 Computer software
url http://umpir.ump.edu.my/id/eprint/25578/
http://umpir.ump.edu.my/id/eprint/25578/
http://umpir.ump.edu.my/id/eprint/25578/
http://umpir.ump.edu.my/id/eprint/25578/1/Empirical%20robustness%20evaluation%20of%20DNA-based%20clustering%20methods.pdf