Flavokawain a induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro
The kava-kava plant (Piper methsyticum) is traditionally known as the pacific elixir by the pacific islanders for its role in a wide range of biological activities. The extract of the roots of this plant contains a variety of interesting molecules including Flavokawain A and this molecule is known t...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science
2014
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| Online Access: | http://umpir.ump.edu.my/id/eprint/25416/ http://umpir.ump.edu.my/id/eprint/25416/1/Flavokawain%20a%20induces%20apoptosis%20in%20MCF-7%20and%20MDA-MB231.PDF |
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| author | Nadiah, Abu M. Nadeem, Akhtar Yeap, Swee Keong Lim, Kian Lam Ho, Wan Yong Aimi Jamil, Zulfadli Abdul Rahman, Omar Mohd Roslan, Sulaiman Mohd Puad, Abdullah Noorjahan Banu, Alitheen |
| author_facet | Nadiah, Abu M. Nadeem, Akhtar Yeap, Swee Keong Lim, Kian Lam Ho, Wan Yong Aimi Jamil, Zulfadli Abdul Rahman, Omar Mohd Roslan, Sulaiman Mohd Puad, Abdullah Noorjahan Banu, Alitheen |
| author_sort | Nadiah, Abu |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | The kava-kava plant (Piper methsyticum) is traditionally known as the pacific elixir by the pacific islanders for its role in a wide range of biological activities. The extract of the roots of this plant contains a variety of interesting molecules including Flavokawain A and this molecule is known to have anti-cancer properties. Breast cancer is still one of the leading diagnosed cancers in women today. The metastatic process is also very pertinent in the progression of tumorigenesis. |
| first_indexed | 2025-11-15T02:38:39Z |
| format | Article |
| id | ump-25416 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T02:38:39Z |
| publishDate | 2014 |
| publisher | Public Library of Science |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-254162019-07-18T02:37:47Z http://umpir.ump.edu.my/id/eprint/25416/ Flavokawain a induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro Nadiah, Abu M. Nadeem, Akhtar Yeap, Swee Keong Lim, Kian Lam Ho, Wan Yong Aimi Jamil, Zulfadli Abdul Rahman, Omar Mohd Roslan, Sulaiman Mohd Puad, Abdullah Noorjahan Banu, Alitheen Q Science (General) The kava-kava plant (Piper methsyticum) is traditionally known as the pacific elixir by the pacific islanders for its role in a wide range of biological activities. The extract of the roots of this plant contains a variety of interesting molecules including Flavokawain A and this molecule is known to have anti-cancer properties. Breast cancer is still one of the leading diagnosed cancers in women today. The metastatic process is also very pertinent in the progression of tumorigenesis. Public Library of Science 2014 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/25416/1/Flavokawain%20a%20induces%20apoptosis%20in%20MCF-7%20and%20MDA-MB231.PDF Nadiah, Abu and M. Nadeem, Akhtar and Yeap, Swee Keong and Lim, Kian Lam and Ho, Wan Yong and Aimi Jamil, Zulfadli and Abdul Rahman, Omar and Mohd Roslan, Sulaiman and Mohd Puad, Abdullah and Noorjahan Banu, Alitheen (2014) Flavokawain a induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro. PLoS ONE, 9 (10). pp. 1-12. ISSN 1932-6203. (Published) https://doi.org/10.1371/journal.pone.0105244 https://doi.org/10.1371/journal.pone.0105244 |
| spellingShingle | Q Science (General) Nadiah, Abu M. Nadeem, Akhtar Yeap, Swee Keong Lim, Kian Lam Ho, Wan Yong Aimi Jamil, Zulfadli Abdul Rahman, Omar Mohd Roslan, Sulaiman Mohd Puad, Abdullah Noorjahan Banu, Alitheen Flavokawain a induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro |
| title | Flavokawain a induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro |
| title_full | Flavokawain a induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro |
| title_fullStr | Flavokawain a induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro |
| title_full_unstemmed | Flavokawain a induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro |
| title_short | Flavokawain a induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro |
| title_sort | flavokawain a induces apoptosis in mcf-7 and mda-mb231 and inhibits the metastatic process in vitro |
| topic | Q Science (General) |
| url | http://umpir.ump.edu.my/id/eprint/25416/ http://umpir.ump.edu.my/id/eprint/25416/ http://umpir.ump.edu.my/id/eprint/25416/ http://umpir.ump.edu.my/id/eprint/25416/1/Flavokawain%20a%20induces%20apoptosis%20in%20MCF-7%20and%20MDA-MB231.PDF |