Metabolic profiling of flavonoids, saponins, alkaloids and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS
The leaves of Vernonia cinerea are widely used for medicinal purposes. Although, different studies have reported on the biological activities of the plant extracts whereas the tentative assignment of secondary metabolites that include flavonoids, saponins, alkaloids, and terpenoids had not been repo...
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| Format: | Article |
| Language: | English |
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Taylor & Francis
2018
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| Online Access: | http://umpir.ump.edu.my/id/eprint/23762/ http://umpir.ump.edu.my/id/eprint/23762/1/Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids.pdf |
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| author | Alara, Oluwaseun Ruth Nour, A. H. Ukaegbu, Chinonso Ishmael Azhari, H. Nour Kabbashi, Nassereldeen Ahmed |
| author_facet | Alara, Oluwaseun Ruth Nour, A. H. Ukaegbu, Chinonso Ishmael Azhari, H. Nour Kabbashi, Nassereldeen Ahmed |
| author_sort | Alara, Oluwaseun Ruth |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | The leaves of Vernonia cinerea are widely used for medicinal purposes. Although, different studies have reported on the biological activities of the plant extracts whereas the tentative assignment of secondary metabolites that include flavonoids, saponins, alkaloids, and terpenoids had not been reported. Thus, this study tentatively assigned the flavonoids, saponins, alkaloids, and terpenoids in the extract of V. cinerea leaves that are mainly responsible for the reported activities. Liquid chromatography-mass spectrometry quadrupole time of flight (LC-Q-TOF-MS) analysis was employed in the assignments. The results obtained showed that a total number of 221 compounds were tentatively assigned in the extract of V. cinerea leaves which include 64 flavonoids, 13 saponins, 36 alkaloids, and 108 terpenoids. These phytochemicals can further be isolated, purified, characterized, and quantified due to their importance. |
| first_indexed | 2025-11-15T02:32:24Z |
| format | Article |
| id | ump-23762 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T02:32:24Z |
| publishDate | 2018 |
| publisher | Taylor & Francis |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-237622020-02-28T08:02:53Z http://umpir.ump.edu.my/id/eprint/23762/ Metabolic profiling of flavonoids, saponins, alkaloids and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS Alara, Oluwaseun Ruth Nour, A. H. Ukaegbu, Chinonso Ishmael Azhari, H. Nour Kabbashi, Nassereldeen Ahmed TP Chemical technology The leaves of Vernonia cinerea are widely used for medicinal purposes. Although, different studies have reported on the biological activities of the plant extracts whereas the tentative assignment of secondary metabolites that include flavonoids, saponins, alkaloids, and terpenoids had not been reported. Thus, this study tentatively assigned the flavonoids, saponins, alkaloids, and terpenoids in the extract of V. cinerea leaves that are mainly responsible for the reported activities. Liquid chromatography-mass spectrometry quadrupole time of flight (LC-Q-TOF-MS) analysis was employed in the assignments. The results obtained showed that a total number of 221 compounds were tentatively assigned in the extract of V. cinerea leaves which include 64 flavonoids, 13 saponins, 36 alkaloids, and 108 terpenoids. These phytochemicals can further be isolated, purified, characterized, and quantified due to their importance. Taylor & Francis 2018 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/23762/1/Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids.pdf Alara, Oluwaseun Ruth and Nour, A. H. and Ukaegbu, Chinonso Ishmael and Azhari, H. Nour and Kabbashi, Nassereldeen Ahmed (2018) Metabolic profiling of flavonoids, saponins, alkaloids and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS. Journal Of Liquid Chromatography & Related Technologies, 41 (11). pp. 1-10. ISSN 1520-572X. (Published) https://doi.org/10.1080/10826076.2018.1511995 https://doi.org/10.1080/10826076.2018.1511995 |
| spellingShingle | TP Chemical technology Alara, Oluwaseun Ruth Nour, A. H. Ukaegbu, Chinonso Ishmael Azhari, H. Nour Kabbashi, Nassereldeen Ahmed Metabolic profiling of flavonoids, saponins, alkaloids and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS |
| title | Metabolic profiling of flavonoids, saponins, alkaloids and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS |
| title_full | Metabolic profiling of flavonoids, saponins, alkaloids and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS |
| title_fullStr | Metabolic profiling of flavonoids, saponins, alkaloids and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS |
| title_full_unstemmed | Metabolic profiling of flavonoids, saponins, alkaloids and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS |
| title_short | Metabolic profiling of flavonoids, saponins, alkaloids and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS |
| title_sort | metabolic profiling of flavonoids, saponins, alkaloids and terpenoids in the extract from vernonia cinerea leaf using lc-q-tof-ms |
| topic | TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/23762/ http://umpir.ump.edu.my/id/eprint/23762/ http://umpir.ump.edu.my/id/eprint/23762/ http://umpir.ump.edu.my/id/eprint/23762/1/Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids.pdf |