Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves
Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic c...
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| Format: | Conference or Workshop Item |
| Language: | English |
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Universiti Malaysia Pahang
2018
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| Online Access: | http://umpir.ump.edu.my/id/eprint/23089/ http://umpir.ump.edu.my/id/eprint/23089/1/Parametric%20Study%20of%20Soxhlet%20Extraction.pdf |
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| author | Alara, Oluwaseun Ruth Nour, A. H. Siti Kholijah, Abdul Mudalip Ukaegbu, Chinonso Ishmael Azhari, H. Nour Kabbashi, Nassereldeen Ahmed |
| author_facet | Alara, Oluwaseun Ruth Nour, A. H. Siti Kholijah, Abdul Mudalip Ukaegbu, Chinonso Ishmael Azhari, H. Nour Kabbashi, Nassereldeen Ahmed |
| author_sort | Alara, Oluwaseun Ruth |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic content (TPC) and total flavonoid content (TFC) from extracts of Vernonia amygdalina leaves were investigated in this study using one-factor-at-a-time experiment (OFAT). Then, the functional group characterization of the extracts at maximum conditions was carried out. The results obtained showed that the three considered extraction parameters significantly influence the recoveries of extraction yield, TPC and TFC. Highest recoveries of extraction yield (14.22±0.19% w/w), TPC (75.94±2.15 mg GAE/g d.w.) and TFC (46.53±1.14 mg QE/g d.w.) were obtained at extraction time of 2 h, solid-to-solvent ratio of 1:20 g/mL and ethanol concentration of 60% v/v. Moreover, 214 National Conference for Postgraduate Research (NCON-PGR) six major peaks were identified from the Soxhlet extraction of V. amygdalina leaves at maximum conditions using Fourier transform infrared spectroscopy (FTIR) analysis. Thus, this study showed that V. amygdalina leaf is a potential source of phenolic compounds which can be influence by the extraction parameters. |
| first_indexed | 2025-11-15T02:29:56Z |
| format | Conference or Workshop Item |
| id | ump-23089 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T02:29:56Z |
| publishDate | 2018 |
| publisher | Universiti Malaysia Pahang |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-230892020-02-28T08:12:09Z http://umpir.ump.edu.my/id/eprint/23089/ Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves Alara, Oluwaseun Ruth Nour, A. H. Siti Kholijah, Abdul Mudalip Ukaegbu, Chinonso Ishmael Azhari, H. Nour Kabbashi, Nassereldeen Ahmed TP Chemical technology Phenolic compounds are important secondary metabolites with different pharmacological activities. The effects of extraction parameters of Soxhlet extraction method which include extraction time, solid-to-solvent ratio and ethanol concentration on the recoveries of extraction yields, total phenolic content (TPC) and total flavonoid content (TFC) from extracts of Vernonia amygdalina leaves were investigated in this study using one-factor-at-a-time experiment (OFAT). Then, the functional group characterization of the extracts at maximum conditions was carried out. The results obtained showed that the three considered extraction parameters significantly influence the recoveries of extraction yield, TPC and TFC. Highest recoveries of extraction yield (14.22±0.19% w/w), TPC (75.94±2.15 mg GAE/g d.w.) and TFC (46.53±1.14 mg QE/g d.w.) were obtained at extraction time of 2 h, solid-to-solvent ratio of 1:20 g/mL and ethanol concentration of 60% v/v. Moreover, 214 National Conference for Postgraduate Research (NCON-PGR) six major peaks were identified from the Soxhlet extraction of V. amygdalina leaves at maximum conditions using Fourier transform infrared spectroscopy (FTIR) analysis. Thus, this study showed that V. amygdalina leaf is a potential source of phenolic compounds which can be influence by the extraction parameters. Universiti Malaysia Pahang 2018-08 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/23089/1/Parametric%20Study%20of%20Soxhlet%20Extraction.pdf Alara, Oluwaseun Ruth and Nour, A. H. and Siti Kholijah, Abdul Mudalip and Ukaegbu, Chinonso Ishmael and Azhari, H. Nour and Kabbashi, Nassereldeen Ahmed (2018) Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves. In: Proceedings Book: National Conference for Postgraduate Research (NCON-PGR 2018) , 28-29 August 2018 , Universiti Malaysia Pahang, Gambang, Pahang. pp. 213-219.. ISBN 978-967-22260-5-5 (Published) http://ncon-pgr.ump.edu.my/index.php/en/download/proceedings-book/file |
| spellingShingle | TP Chemical technology Alara, Oluwaseun Ruth Nour, A. H. Siti Kholijah, Abdul Mudalip Ukaegbu, Chinonso Ishmael Azhari, H. Nour Kabbashi, Nassereldeen Ahmed Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| title | Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| title_full | Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| title_fullStr | Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| title_full_unstemmed | Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| title_short | Parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| title_sort | parametric study of soxhlet extraction of phenolic compounds from vernonia amygdalina leaves |
| topic | TP Chemical technology |
| url | http://umpir.ump.edu.my/id/eprint/23089/ http://umpir.ump.edu.my/id/eprint/23089/ http://umpir.ump.edu.my/id/eprint/23089/1/Parametric%20Study%20of%20Soxhlet%20Extraction.pdf |