Performance of Glycemic Control Protocol and Virtual Trial
Model-based glycemic control offers direct management of patient-specific variability and better adaptive control. Implementation of the model-based glycemic control has the potential to reduce hyperglycemia episodes, mortality and morbidity as seen in some successful TGC. The design of any TGC must...
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| Language: | English |
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Publishing Technology
2017
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| Online Access: | http://umpir.ump.edu.my/id/eprint/19703/ http://umpir.ump.edu.my/id/eprint/19703/1/fkm-2017-ummu-performance%20of%20glycemic.pdf |
| _version_ | 1848820942917074944 |
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| author | Fatanah, M. Suhaimi Ummu Kulthum, Jamaludin Normy Norfiza, A. Razak Azrina, Md Ralib Mohd Basri, Mat Nor |
| author_facet | Fatanah, M. Suhaimi Ummu Kulthum, Jamaludin Normy Norfiza, A. Razak Azrina, Md Ralib Mohd Basri, Mat Nor |
| author_sort | Fatanah, M. Suhaimi |
| building | UMP Institutional Repository |
| collection | Online Access |
| description | Model-based glycemic control offers direct management of patient-specific variability and better adaptive control. Implementation of the model-based glycemic control has the potential to reduce hyperglycemia episodes, mortality and morbidity as seen in some successful TGC. The design of any TGC must consider not only the glycemic target range but also safety and efficacy of the insulin therapy. This paper presents the evaluation of glycemic control protocol adapted in the ICU of Tengku Ampuan Afzan Hospital. Virtual trials method is used to simulate the controller algorithm on a virtual patient with feed variation factor. Data from actual clinical and the virtual trial are compared to analyze the protocol performance concerning blood glucose outcome and insulin efficacy. A stochastic model is also used to indicate metabolic response and metabolic variation of the cohort. |
| first_indexed | 2025-11-15T02:17:28Z |
| format | Article |
| id | ump-19703 |
| institution | Universiti Malaysia Pahang |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T02:17:28Z |
| publishDate | 2017 |
| publisher | Publishing Technology |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ump-197032018-11-30T01:56:38Z http://umpir.ump.edu.my/id/eprint/19703/ Performance of Glycemic Control Protocol and Virtual Trial Fatanah, M. Suhaimi Ummu Kulthum, Jamaludin Normy Norfiza, A. Razak Azrina, Md Ralib Mohd Basri, Mat Nor Q Science (General) QA Mathematics R Medicine (General) Model-based glycemic control offers direct management of patient-specific variability and better adaptive control. Implementation of the model-based glycemic control has the potential to reduce hyperglycemia episodes, mortality and morbidity as seen in some successful TGC. The design of any TGC must consider not only the glycemic target range but also safety and efficacy of the insulin therapy. This paper presents the evaluation of glycemic control protocol adapted in the ICU of Tengku Ampuan Afzan Hospital. Virtual trials method is used to simulate the controller algorithm on a virtual patient with feed variation factor. Data from actual clinical and the virtual trial are compared to analyze the protocol performance concerning blood glucose outcome and insulin efficacy. A stochastic model is also used to indicate metabolic response and metabolic variation of the cohort. Publishing Technology 2017-06-01 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/19703/1/fkm-2017-ummu-performance%20of%20glycemic.pdf Fatanah, M. Suhaimi and Ummu Kulthum, Jamaludin and Normy Norfiza, A. Razak and Azrina, Md Ralib and Mohd Basri, Mat Nor (2017) Performance of Glycemic Control Protocol and Virtual Trial. Advanced Science Letters, 23 (6). pp. 5415-5418. ISSN 1936-6612. (Published) https://doi.org/10.1166/asl.2017.7389 doi: 10.1166/asl.2017.7389 |
| spellingShingle | Q Science (General) QA Mathematics R Medicine (General) Fatanah, M. Suhaimi Ummu Kulthum, Jamaludin Normy Norfiza, A. Razak Azrina, Md Ralib Mohd Basri, Mat Nor Performance of Glycemic Control Protocol and Virtual Trial |
| title | Performance of Glycemic Control Protocol and Virtual Trial |
| title_full | Performance of Glycemic Control Protocol and Virtual Trial |
| title_fullStr | Performance of Glycemic Control Protocol and Virtual Trial |
| title_full_unstemmed | Performance of Glycemic Control Protocol and Virtual Trial |
| title_short | Performance of Glycemic Control Protocol and Virtual Trial |
| title_sort | performance of glycemic control protocol and virtual trial |
| topic | Q Science (General) QA Mathematics R Medicine (General) |
| url | http://umpir.ump.edu.my/id/eprint/19703/ http://umpir.ump.edu.my/id/eprint/19703/ http://umpir.ump.edu.my/id/eprint/19703/ http://umpir.ump.edu.my/id/eprint/19703/1/fkm-2017-ummu-performance%20of%20glycemic.pdf |