Rhodomyrtus Tomentosa: A Phytochemical and Pharmacological Review

Rhodomyrtus tomentosa is a common wood, prevalent in areas with undemanding soil conditions and resistant toward pests and diseases. The plant can be found in China, Taiwan, Philippines, Malaysia, Indonesia, and Vietnam. Literature and artwork indicate that R. tomentosa played an important holistic...

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Main Authors: Hazrulrizawati, Hamid, Zeyohannes, Senait Sileshi, M. M., Yusoff
Format: Article
Language:English
Published: Innovare Academic Sciences Pvt Ltd 2017
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/17135/
http://umpir.ump.edu.my/id/eprint/17135/1/12773-76387-1-PB.pdf
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author Hazrulrizawati, Hamid
Zeyohannes, Senait Sileshi
M. M., Yusoff
author_facet Hazrulrizawati, Hamid
Zeyohannes, Senait Sileshi
M. M., Yusoff
author_sort Hazrulrizawati, Hamid
building UMP Institutional Repository
collection Online Access
description Rhodomyrtus tomentosa is a common wood, prevalent in areas with undemanding soil conditions and resistant toward pests and diseases. The plant can be found in China, Taiwan, Philippines, Malaysia, Indonesia, and Vietnam. Literature and artwork indicate that R. tomentosa played an important holistic role in the daily lives of several ancient cultures, providing medicinal benefits. R. tomentosa exhibits a wide spectrum of pharmacological effects and has been used to treat colic diarrhea, wounds, heartburn, abscesses, gynecopathy, and as a pain killer. R. tomentosa was used in traditional Chinese medicine to treat urinary tract infection. 42 compounds have been isolated from this plant and structurally elucidated. They comprise phloroglucinol, flavonoid, terpenoid, anthracene glycoside, tannin, and other compounds. Rhodomyrtone, a member of the acylphloroglucinols demonstrated a significant activity against a wide range of Gram-positive bacteria. Rhodomyrtone exhibited both antimicrobial and anti-infective activities. Several biological activities have been documented as antibacterial, antifungal, antimalarial, osteogenic, antioxidant, and anti-inflammatory. R. tomentosa has been studied extensively for alternative antimicrobial agents. Although rhodomyrtone exhibited potential activity with a very low minimum inhibitory concentration value, the mechanisms of action of this compound are still unclear. Furthermore, toxicity studies on it extract to validate pharmacological activities are required.
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spelling ump-171352018-07-26T07:49:29Z http://umpir.ump.edu.my/id/eprint/17135/ Rhodomyrtus Tomentosa: A Phytochemical and Pharmacological Review Hazrulrizawati, Hamid Zeyohannes, Senait Sileshi M. M., Yusoff RM Therapeutics. Pharmacology Rhodomyrtus tomentosa is a common wood, prevalent in areas with undemanding soil conditions and resistant toward pests and diseases. The plant can be found in China, Taiwan, Philippines, Malaysia, Indonesia, and Vietnam. Literature and artwork indicate that R. tomentosa played an important holistic role in the daily lives of several ancient cultures, providing medicinal benefits. R. tomentosa exhibits a wide spectrum of pharmacological effects and has been used to treat colic diarrhea, wounds, heartburn, abscesses, gynecopathy, and as a pain killer. R. tomentosa was used in traditional Chinese medicine to treat urinary tract infection. 42 compounds have been isolated from this plant and structurally elucidated. They comprise phloroglucinol, flavonoid, terpenoid, anthracene glycoside, tannin, and other compounds. Rhodomyrtone, a member of the acylphloroglucinols demonstrated a significant activity against a wide range of Gram-positive bacteria. Rhodomyrtone exhibited both antimicrobial and anti-infective activities. Several biological activities have been documented as antibacterial, antifungal, antimalarial, osteogenic, antioxidant, and anti-inflammatory. R. tomentosa has been studied extensively for alternative antimicrobial agents. Although rhodomyrtone exhibited potential activity with a very low minimum inhibitory concentration value, the mechanisms of action of this compound are still unclear. Furthermore, toxicity studies on it extract to validate pharmacological activities are required. Innovare Academic Sciences Pvt Ltd 2017 Article PeerReviewed application/pdf en cc_by http://umpir.ump.edu.my/id/eprint/17135/1/12773-76387-1-PB.pdf Hazrulrizawati, Hamid and Zeyohannes, Senait Sileshi and M. M., Yusoff (2017) Rhodomyrtus Tomentosa: A Phytochemical and Pharmacological Review. Asian Journal of Pharmaceutical and Clinical Research, 10 (1). pp. 1-7. ISSN 0974-2441(print); 2455-3891(online). (Published) http://dx.doi.org/10.22159/ajpcr.2017.v10i1.12773 doi: 10.22159/ajpcr.2017.v10i1.12773
spellingShingle RM Therapeutics. Pharmacology
Hazrulrizawati, Hamid
Zeyohannes, Senait Sileshi
M. M., Yusoff
Rhodomyrtus Tomentosa: A Phytochemical and Pharmacological Review
title Rhodomyrtus Tomentosa: A Phytochemical and Pharmacological Review
title_full Rhodomyrtus Tomentosa: A Phytochemical and Pharmacological Review
title_fullStr Rhodomyrtus Tomentosa: A Phytochemical and Pharmacological Review
title_full_unstemmed Rhodomyrtus Tomentosa: A Phytochemical and Pharmacological Review
title_short Rhodomyrtus Tomentosa: A Phytochemical and Pharmacological Review
title_sort rhodomyrtus tomentosa: a phytochemical and pharmacological review
topic RM Therapeutics. Pharmacology
url http://umpir.ump.edu.my/id/eprint/17135/
http://umpir.ump.edu.my/id/eprint/17135/
http://umpir.ump.edu.my/id/eprint/17135/
http://umpir.ump.edu.my/id/eprint/17135/1/12773-76387-1-PB.pdf