Nanoscale Metal Particles as Nanocarriers in Targeted Drug Delivery System

In the recent years, noble metal particles such as gold (Au) and silver (Ag) have been used progressively as efficient and safe nanoscale drug carriers in treating malignant as cites of cancerous cells. These single crystal structures of functionalised thearapeutic particles with the size le...

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Main Authors: Nurul Akmal, Che Lah, Samykano, Mahendran, Trigueros, Sonia
Format: Article
Language:English
Published: MedCrave 2016
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/16455/
http://umpir.ump.edu.my/id/eprint/16455/1/fkm-2016-akma-Nanoscale%20Metal%20Particles.pdf
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author Nurul Akmal, Che Lah
Samykano, Mahendran
Trigueros, Sonia
author_facet Nurul Akmal, Che Lah
Samykano, Mahendran
Trigueros, Sonia
author_sort Nurul Akmal, Che Lah
building UMP Institutional Repository
collection Online Access
description In the recent years, noble metal particles such as gold (Au) and silver (Ag) have been used progressively as efficient and safe nanoscale drug carriers in treating malignant as cites of cancerous cells. These single crystal structures of functionalised thearapeutic particles with the size less than 100 nm in diameter had proven offered an excellent function to modulate the oxidative stress and toxicity at affected membrane cells particularly to achieve the site-specific delivery of drugs. This mini-review will highlight the current advances of Au and Ag nanoscale particles as smart chemotherapeutic molecule carriers to these malignancies in impeding cancer cell activities locally. The paper also reviewed valuable insights of their efficacy in maintaining and precisely control the drugs release level within the therapeutic windows.
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publishDate 2016
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spelling ump-164552017-03-08T01:03:41Z http://umpir.ump.edu.my/id/eprint/16455/ Nanoscale Metal Particles as Nanocarriers in Targeted Drug Delivery System Nurul Akmal, Che Lah Samykano, Mahendran Trigueros, Sonia RM Therapeutics. Pharmacology In the recent years, noble metal particles such as gold (Au) and silver (Ag) have been used progressively as efficient and safe nanoscale drug carriers in treating malignant as cites of cancerous cells. These single crystal structures of functionalised thearapeutic particles with the size less than 100 nm in diameter had proven offered an excellent function to modulate the oxidative stress and toxicity at affected membrane cells particularly to achieve the site-specific delivery of drugs. This mini-review will highlight the current advances of Au and Ag nanoscale particles as smart chemotherapeutic molecule carriers to these malignancies in impeding cancer cell activities locally. The paper also reviewed valuable insights of their efficacy in maintaining and precisely control the drugs release level within the therapeutic windows. MedCrave 2016 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/16455/1/fkm-2016-akma-Nanoscale%20Metal%20Particles.pdf Nurul Akmal, Che Lah and Samykano, Mahendran and Trigueros, Sonia (2016) Nanoscale Metal Particles as Nanocarriers in Targeted Drug Delivery System. Journal of Nanomedicine Research, 4 (2). pp. 1-6. ISSN 2377-4282. (Published) http://medcraveonline.com/JNMR/JNMR-04-00086.pdf
spellingShingle RM Therapeutics. Pharmacology
Nurul Akmal, Che Lah
Samykano, Mahendran
Trigueros, Sonia
Nanoscale Metal Particles as Nanocarriers in Targeted Drug Delivery System
title Nanoscale Metal Particles as Nanocarriers in Targeted Drug Delivery System
title_full Nanoscale Metal Particles as Nanocarriers in Targeted Drug Delivery System
title_fullStr Nanoscale Metal Particles as Nanocarriers in Targeted Drug Delivery System
title_full_unstemmed Nanoscale Metal Particles as Nanocarriers in Targeted Drug Delivery System
title_short Nanoscale Metal Particles as Nanocarriers in Targeted Drug Delivery System
title_sort nanoscale metal particles as nanocarriers in targeted drug delivery system
topic RM Therapeutics. Pharmacology
url http://umpir.ump.edu.my/id/eprint/16455/
http://umpir.ump.edu.my/id/eprint/16455/
http://umpir.ump.edu.my/id/eprint/16455/1/fkm-2016-akma-Nanoscale%20Metal%20Particles.pdf