Persistency and permanency of two stages splicing languages based on DNA recombination process by using Yusof-Goode (Y-G) approach

The study of the biological process of deoxyribonucleic acid (DNA) splicing was investigated by Yusof in 2012 as a translucent approach under framework of formal languages theory. The investigation was achieved by proposing a new symbolization representing the rule in splicing system called Yusof-Go...

Full description

Bibliographic Details
Main Author: Mohammad Hassan, Mudaber
Format: Thesis
Language:English
Published: 2015
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/11245/
http://umpir.ump.edu.my/id/eprint/11245/19/Persistency%20and%20permanency%20of%20two%20stages%20splicing%20languages%20based%20on%20DNA%20recombination%20process%20by%20using%20Yusof-Goode%20%28Y-G%29%20approach.pdf
_version_ 1848818958009892864
author Mohammad Hassan, Mudaber
author_facet Mohammad Hassan, Mudaber
author_sort Mohammad Hassan, Mudaber
building UMP Institutional Repository
collection Online Access
description The study of the biological process of deoxyribonucleic acid (DNA) splicing was investigated by Yusof in 2012 as a translucent approach under framework of formal languages theory. The investigation was achieved by proposing a new symbolization representing the rule in splicing system called Yusof-Goode (Y-G) rule associated with Y-G splicing system. A laboratory experiment is usually performed to show the DNA splicing process under the existence of restriction enzyme and appropriate ligase. This laboratory experiment is time consuming process and it can incur a lot of expenses. In addition, to accomplish the reaction up to two stages the generating recombining DNA molecules must have persistency concept. Thus, to overcome this problem, mathematical approach via Y-G model is applied to introduce the new concept of splicing system at two stages with respect to two initial strings and two rules. Furthermore, the existence relation between the families of stage one and stage two splicing languages are investigated. In this investigation, some sufficient conditions for persistency and permanency of two stages DNA splicing languages according to the number of cutting sites of initial strings and properties of rules are provided. The de Bruijn graph is used to predict the persistency and permanency of two stages splicing languages. A user friendly interface as an alternative of wet-lab experiment is coded using Microsoft Visual C Sharp (C#) to predict the persistency and permanency, and the relations between two stages (stage one and stage two) splicing languages.
first_indexed 2025-11-15T01:45:55Z
format Thesis
id ump-11245
institution Universiti Malaysia Pahang
institution_category Local University
language English
last_indexed 2025-11-15T01:45:55Z
publishDate 2015
recordtype eprints
repository_type Digital Repository
spelling ump-112452021-11-02T03:39:35Z http://umpir.ump.edu.my/id/eprint/11245/ Persistency and permanency of two stages splicing languages based on DNA recombination process by using Yusof-Goode (Y-G) approach Mohammad Hassan, Mudaber QA Mathematics The study of the biological process of deoxyribonucleic acid (DNA) splicing was investigated by Yusof in 2012 as a translucent approach under framework of formal languages theory. The investigation was achieved by proposing a new symbolization representing the rule in splicing system called Yusof-Goode (Y-G) rule associated with Y-G splicing system. A laboratory experiment is usually performed to show the DNA splicing process under the existence of restriction enzyme and appropriate ligase. This laboratory experiment is time consuming process and it can incur a lot of expenses. In addition, to accomplish the reaction up to two stages the generating recombining DNA molecules must have persistency concept. Thus, to overcome this problem, mathematical approach via Y-G model is applied to introduce the new concept of splicing system at two stages with respect to two initial strings and two rules. Furthermore, the existence relation between the families of stage one and stage two splicing languages are investigated. In this investigation, some sufficient conditions for persistency and permanency of two stages DNA splicing languages according to the number of cutting sites of initial strings and properties of rules are provided. The de Bruijn graph is used to predict the persistency and permanency of two stages splicing languages. A user friendly interface as an alternative of wet-lab experiment is coded using Microsoft Visual C Sharp (C#) to predict the persistency and permanency, and the relations between two stages (stage one and stage two) splicing languages. 2015-03 Thesis NonPeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/11245/19/Persistency%20and%20permanency%20of%20two%20stages%20splicing%20languages%20based%20on%20DNA%20recombination%20process%20by%20using%20Yusof-Goode%20%28Y-G%29%20approach.pdf Mohammad Hassan, Mudaber (2015) Persistency and permanency of two stages splicing languages based on DNA recombination process by using Yusof-Goode (Y-G) approach. Masters thesis, Universiti Malaysia Pahang (Contributors, UNSPECIFIED: UNSPECIFIED).
spellingShingle QA Mathematics
Mohammad Hassan, Mudaber
Persistency and permanency of two stages splicing languages based on DNA recombination process by using Yusof-Goode (Y-G) approach
title Persistency and permanency of two stages splicing languages based on DNA recombination process by using Yusof-Goode (Y-G) approach
title_full Persistency and permanency of two stages splicing languages based on DNA recombination process by using Yusof-Goode (Y-G) approach
title_fullStr Persistency and permanency of two stages splicing languages based on DNA recombination process by using Yusof-Goode (Y-G) approach
title_full_unstemmed Persistency and permanency of two stages splicing languages based on DNA recombination process by using Yusof-Goode (Y-G) approach
title_short Persistency and permanency of two stages splicing languages based on DNA recombination process by using Yusof-Goode (Y-G) approach
title_sort persistency and permanency of two stages splicing languages based on dna recombination process by using yusof-goode (y-g) approach
topic QA Mathematics
url http://umpir.ump.edu.my/id/eprint/11245/
http://umpir.ump.edu.my/id/eprint/11245/19/Persistency%20and%20permanency%20of%20two%20stages%20splicing%20languages%20based%20on%20DNA%20recombination%20process%20by%20using%20Yusof-Goode%20%28Y-G%29%20approach.pdf