Finite and infinite singular arc in Chemotherapy schedulling using optimal control theory / Marziehalsadat Jazayeri Shooshtari

Cancer is one of the leading causes of death globally and chemotherapy being an effective approach for treatment has to be closely monitored and scheduled. In this work optimal control theory is used to schedule the administration of Temozolomide as a chemo drug. After obtaining the Hamiltonian f...

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Main Author: Marziehalsadat, Jazyeri Shooshtari
Format: Thesis
Published: 2018
Subjects:
Online Access:http://studentsrepo.um.edu.my/9975/
http://studentsrepo.um.edu.my/9975/1/Marziehalsadat_Jazyeri_Shootshtari.jpg
http://studentsrepo.um.edu.my/9975/8/marzieha.pdf
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author Marziehalsadat, Jazyeri Shooshtari
author_facet Marziehalsadat, Jazyeri Shooshtari
author_sort Marziehalsadat, Jazyeri Shooshtari
building UM Research Repository
collection Online Access
description Cancer is one of the leading causes of death globally and chemotherapy being an effective approach for treatment has to be closely monitored and scheduled. In this work optimal control theory is used to schedule the administration of Temozolomide as a chemo drug. After obtaining the Hamiltonian function the cases of singular arcs are discussed. It is shown that the control of this treatment consists of both finite order and infinite order singular arcs. Finite order singular arcs in this work are of the third order and can be derived after deriving the switching function (
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format Thesis
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institution University Malaya
institution_category Local University
last_indexed 2025-11-14T13:52:01Z
publishDate 2018
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spelling um-99752021-03-08T00:53:51Z Finite and infinite singular arc in Chemotherapy schedulling using optimal control theory / Marziehalsadat Jazayeri Shooshtari Marziehalsadat, Jazyeri Shooshtari T Technology (General) Cancer is one of the leading causes of death globally and chemotherapy being an effective approach for treatment has to be closely monitored and scheduled. In this work optimal control theory is used to schedule the administration of Temozolomide as a chemo drug. After obtaining the Hamiltonian function the cases of singular arcs are discussed. It is shown that the control of this treatment consists of both finite order and infinite order singular arcs. Finite order singular arcs in this work are of the third order and can be derived after deriving the switching function ( 2018-12 Thesis NonPeerReviewed application/pdf http://studentsrepo.um.edu.my/9975/1/Marziehalsadat_Jazyeri_Shootshtari.jpg application/pdf http://studentsrepo.um.edu.my/9975/8/marzieha.pdf Marziehalsadat, Jazyeri Shooshtari (2018) Finite and infinite singular arc in Chemotherapy schedulling using optimal control theory / Marziehalsadat Jazayeri Shooshtari. Masters thesis, University of Malaya. http://studentsrepo.um.edu.my/9975/
spellingShingle T Technology (General)
Marziehalsadat, Jazyeri Shooshtari
Finite and infinite singular arc in Chemotherapy schedulling using optimal control theory / Marziehalsadat Jazayeri Shooshtari
title Finite and infinite singular arc in Chemotherapy schedulling using optimal control theory / Marziehalsadat Jazayeri Shooshtari
title_full Finite and infinite singular arc in Chemotherapy schedulling using optimal control theory / Marziehalsadat Jazayeri Shooshtari
title_fullStr Finite and infinite singular arc in Chemotherapy schedulling using optimal control theory / Marziehalsadat Jazayeri Shooshtari
title_full_unstemmed Finite and infinite singular arc in Chemotherapy schedulling using optimal control theory / Marziehalsadat Jazayeri Shooshtari
title_short Finite and infinite singular arc in Chemotherapy schedulling using optimal control theory / Marziehalsadat Jazayeri Shooshtari
title_sort finite and infinite singular arc in chemotherapy schedulling using optimal control theory / marziehalsadat jazayeri shooshtari
topic T Technology (General)
url http://studentsrepo.um.edu.my/9975/
http://studentsrepo.um.edu.my/9975/1/Marziehalsadat_Jazyeri_Shootshtari.jpg
http://studentsrepo.um.edu.my/9975/8/marzieha.pdf