Computational design strategy of pharmaceutical co-crystals: A case study of anti-cancer drugs / Nadia Hanim Sabri

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Computational design strategy of pharmaceutical co-crystals: A case study of anti-cancer drugs / Nadia Hanim Sabri

Thymidylate synthase (TS) is a biomarker for fluoropyrimidine-based chemotherapy that provides the sole intracellular de novo source of thymidylate, an essential precursor to DNA synthesis. Antifolate drug and fluoropyrimidine-based drug have potential to disrupt TS activity by nucleotide and ant...

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Bibliographic Details
Main Author:	Nadia Hanim , Sabri
Format:	Thesis
Published:	2018
Subjects:	Q Science (General) QD Chemistry
Online Access:	http://studentsrepo.um.edu.my/9593/ http://studentsrepo.um.edu.my/9593/1/Nadia_Hanim_Sabri.pdf http://studentsrepo.um.edu.my/9593/6/nadia_hanim.pdf

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