Synthesis of new 1,2,4-triazole and 1,3,4-oxadiazole derivatives derived from 2-ethylsulfanyl benzohydrazide and evaluation of their biological activities / Nafal Nazar Bahjat

QR Code

Synthesis of new 1,2,4-triazole and 1,3,4-oxadiazole derivatives derived from 2-ethylsulfanyl benzohydrazide and evaluation of their biological activities / Nafal Nazar Bahjat

The new 1-acylthiosemicarbazides derivatives 3.3-3.7 were synthesised by the reaction of active intermediate 2-(ethylsulfanyl)benzohydrazide 3.2 with various aryl isothiocyanates. The cyclisation of thiosemicarbazide derivatives in a basic medium (aqueous NaOH, 4 N) yielded compounds 3.8-3.12, while...

Full description

Bibliographic Details
Main Author:	Nafal Nazar , Bahjat
Format:	Thesis
Published:	2016
Subjects:	Q Science (General) QD Chemistry
Online Access:	http://studentsrepo.um.edu.my/7245/ http://studentsrepo.um.edu.my/7245/4/nafal.pdf

Similar Items

Synthesis of new 1,2,4-triazole and 1,3,4-oxadiazole derivatives derived from 2-ethylsulfanyl benzohydrazide and evaluation of their biological activities / Nafal Nazar Bahjat
by: Nafal Nazar, Bahjat
Published: (2016)

Synthesis, Characterization And Anti-Mycobacterial Activity Of New 1,3,4-Oxadiazole Derivatives
by: Hasmaruddin, Nurul Syazana
Published: (2020)

Synthesis, Characterization and Urease Inhibiting Derivatives of 5-(3,4-Methylenedioxyphenyl)-1,3,4-Oxadiazol-2-thiol
by: Akhtar, Muhammad Nadeem, et al.
Published: (2014)

Synthesis and characterization of 1,2,4-triazolo-1,3,4-thiadiazole derivatives
by: Cheng, Yun Ru
Published: (2022)

Synthesis and characterization of 1,3,4-oxadiazoles bearing an indole ring
by: Ng, Yu Xuan
Published: (2020)

Crystal structure of 2-(adamantan-1-yl)-5-(4-bromophenyl)-1,3,4-oxadiazole
by: Alzoman, Nourah Z., et al.
Published: (2014)

S-Alkylated/aralkylated 2-(1H-indol-3-yl-methyl)-1,3,4- oxadiazole-5-thiol derivatives. 1. Synthesis and Characterization
by: Rubab, Kaniz, et al.
Published: (2016)

Synthesis of N'-Substituted-2-((5-(4-Chlorophenyl)-1,3,4-Oxadiazol-2-ylthio Acetohydrazie Derivatives as Suitable Antibacterial Agents
by: Akhtar, Muhammad Nadeem, et al.
Published: (2015)

Synthesis, characterization and antioxidant activity of 1,3,4-oxadiazoles incorporating an indole moiety
by: Chong, Jien Lee
Published: (2019)

Synthesis, characterization and antioxidant activity of 1,3,4-oxadiazoles bearing an indole ring
by: Kong, Kian Liang
Published: (2019)

Synthesis, characterization and antioxidant activity of 1,3,4-oxadiazoles incorporating an indole moiety
by: Chong, Jien Lee
Published: (2019)

Synthesis, characterization and antioxidant activity of 1,3,4-oxadiazoles bearing an indole ring
by: Kong, Kian Liang
Published: (2019)

Synthesis, Characterisation And Cytotoxicity Study Of Some New 1,2,4-Triazole Derivatives
by: Mohsin Slaihim, Mukhlif
Published: (2017)

Synthesis, characterization and antioxidant activity of 1,2,4-triazole and its Schiff base derivatives
by: Wong, Wen Li
Published: (2023)

Synthesis and characterization of 1,2,4-triazolo-1,3,4-thiadiazoles
by: Loo, Xin Tong
Published: (2022)

Synthesis, Antimicrobial Evaluation and Hemolytic Activity of 2-[[5-alkyl/aralkyl substituted-1,3,4-oxadiazol-2-yl]thio]-N-[4-(4-morpholinyl)phenyl]acetamide derivatives
by: Akhtar, Muhammad Nadeem, et al.
Published: (2017)

3-Phenyl-1H-1,2,4-triazol-5-amine-5-phenyl-1H-1,2,4-triazol-3-amine (1/1).
by: Dolzhenko, Anton, et al.
Published: (2009)

Synthesis and antimicrobial activity of 1-(5-Mercapto-1,3,4-Oxadiazol-2-yl) -2-(Pyridine-2-ylamino)ethanone
by: Jumat Salimon,, et al.
Published: (2011)

Synthesis and Biological Evaluation of Novel Substituted 1,3,4-thiadiazole and 2,6-di aryl substituted imidazo [2,1- b] [1,3,4]thiadiazole Derivatives
by: Hegde, Gurumurthy, et al.
Published: (2014)

Novel 1,3,4-oxadiazole induces anticancer activity by targeting NF-ÎºB in hepatocellular carcinoma cells
by: Mohan, C., et al.
Published: (2018)

Palladium (0) catalyzed synthesis of thiophene based 1,3,4-oxadiazoles their reactivities and potential nonlinear optical properties
by: Abbas, Mujahad, Abbas, et al.
Published: (2020)

4-(4-Chlorophenyl)-4,5-dihydro-1H-1,2,4-triazole-5-thione
by: Yeo, Chien Ing *, et al.
Published: (2019)

Crystal structure of 3-[(4-benzylpiperazin-1-yl)methyl]-5-(thiophen-2-yl)- 2,3-dihydro-1,3,4-oxadiazole-2-thione
by: Al-Omary, Fatmah A. M., et al.
Published: (2015)

3-(Adamantan-1-yl)-4-benzyl-1H-1,2,4-triazole-5(4H)-thione
by: A. M. Al-Omary, Fatmah, et al.
Published: (2014)

Crystal Structures And Analysis Of 1,2,4 Triazole And Pyrazole Compounds
by: Goh , Jia Hao
Published: (2011)

Crystal structure of 2-(adamantan-1-yl)-5-(3,5-dinitrophenyl)-1,3,4-oxadiazole, C18H18N4O5
by: Al-Wahaibi, Lamya H., et al.
Published: (2022)

4-Amino-3-(3-methoxybenzyl)-1H-1,2,4-triazole-5(4H)-thione
by: Hegde, Gurumurthy, et al.
Published: (2013)

3,5-Bis(4-hydroxyphenyl)-4H-1,2,4-triazol-4-amine monohydrate
by: Silong, Sidik, et al.
Published: (2010)

Crystal structure of 3-(adamantan-1-yl)- 4-(4-chlorophenyl)-1H-1,2,4-triazole- 5(4H)-thione
by: Al-Wabli, Reem I., et al.
Published: (2015)

3-Pyridin-2-yl-1H-1,2,4-triazol-5-amine.
by: Dolzhenko, Anton, et al.
Published: (2009)

N-Carbethoxy-N'-[3-(4-methylphenyl)-1H-1,2,4-triazol-5-yl]thiourea
by: Dolzhenko, Anton, et al.
Published: (2010)

3-(Adamantan-1-yl)-4-ethyl-1-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1H-1,2,4-triazole-5(4H)-thione
by: El-Emam, Ali A., et al.
Published: (2014)

One-pot green synthesis of some novel n-substituted 5-amino-1,3,4-thiadiazole derivatives
by: Habibi, Azizollah, et al.
Published: (2020)

Synthesis, Structural Analysis and Screening of Some Novel 5-Substituted Aryl/Aralkyl-1,3,4-Oxadiazol-2-Yl 4-(Morpholin-4-Ylsulfonyl)Benzyl Sulfides as Potential Antibacterial Agents
by: Akhtar, Muhammad Nadeem, et al.
Published: (2015)

Crystal structure of ethyl 4-{[5-(adamantan-1-yl)-2-sulfanylidene-2,3-dihydro-1,3,4-oxadiazol-3-yl]methyl}piperazine-1-carboxylate, C20H30N4O3S
by: Al-Sanea, Mohammad M., et al.
Published: (2023)

Synthesis of 3-(5-amino-1H-1,2,4-triazol-3-yl) propanamides and their tautomerism
by: Lim, Felicia Phei Lin, et al.
Published: (2018)

Synthesis of 3-(5-amino-1H-1,2,4-triazol-3-yl)propanamides and their tautomerism
by: Lim, F., et al.
Published: (2018)

N-Carbethoxy-N'-(3-phenyl-1H-1,2,4-triazol-5-yl)thiourea
by: Dolzhenko, Anton, et al.
Published: (2010)

Synthesis Pharmacological Evaluation, Molecular Docking And Cytotoxicty Studies On Some N-Substituted 5-[(4-Chlorophenoxy)Methyl]-1,3,4-Oxadiazole-2yl-2-Sulfanyl Acetamides
by: Siddiqui, Sabahat Zahra, et al.
Published: (2014)

Convergent synthesis of new N -substituted 2-{[5-(1H -indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl} acetamides as suitable therapeutic agents
by: Rubab, Kaniz, et al.
Published: (2015)