Alpha-lipoic acid and mesuagenin c-induced co-regulation of nf-κβ-cytokines and chemokines via pi3k-akt/gsk-3β and erk1/2 in in vitro neuronal models / Muhamad Noor Alfarizal Kamarudin

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Alpha-lipoic acid and mesuagenin c-induced co-regulation of nf-κβ-cytokines and chemokines via pi3k-akt/gsk-3β and erk1/2 in in vitro neuronal models / Muhamad Noor Alfarizal Kamarudin

(R-)(+)-α-lipoic acid and mesuagenin c were shown to protect the NG108-15 cells against H2O2-induced cell death by mitigating the caspase-dependent mitochondrial-mediated pathway. (R)-(+)-α-lipoic acid activated both mTORC1 and mTORC2 components whereas mesuagenin c only activated mTORC2 component w...

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Bibliographic Details
Main Author:	Muhamad Noor Alfarizal , Kamarudin
Format:	Thesis
Published:	2016
Subjects:	Q Science (General) QD Chemistry
Online Access:	http://studentsrepo.um.edu.my/6776/ http://studentsrepo.um.edu.my/6776/1/alfarizal.pdf

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