Benzimidazole derivatives as potential dual inhibitors for poly (adp-ribose) polymerase-1 and dihydroorotate
dehydrogenase / Iskandar Abdullah

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Benzimidazole derivatives as potential dual inhibitors for poly (adp-ribose) polymerase-1 and dihydroorotate dehydrogenase / Iskandar Abdullah

Poly (ADP-ribose) polymerases (PARPs) play diverse roles in various cellular processes that involve DNA repair and programmed cell death. Amongst these polymerases is PARP-1, which is the key DNA damage-sensing enzyme that acts as an initiator for the DNA repair mechanism. Dihydroorotate dehydrogen...

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Bibliographic Details
Main Author:	Iskandar, Abdullah
Format:	Thesis
Published:	2015
Subjects:	Q Science (General)
Online Access:	http://studentsrepo.um.edu.my/6525/ http://studentsrepo.um.edu.my/6525/1/iskandar.pdf

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