Determination of hydroxyproline in Kalanchoe pinnata by HPLC / Nurul Nadia binti Zainal Abidin

Kalanchoe pinnata is an important plant which has many traditional medicinal uses. In this work, hydroxyproline was extracted from Kalanchoe pinnata. Determination of hydroxyproline in this plant was done using HPLC. Hydroxyproline is one of the element for the formation of collagen. There are three...

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Main Author: Zainal Abidin, Nurul Nadia
Format: Thesis
Published: 2013
Subjects:
Online Access:http://studentsrepo.um.edu.my/5786/
http://studentsrepo.um.edu.my/5786/1/DETERMINATION_OF_HYDROXYPROLINE_IN_KALANCHOE_PINNATA_BY_HPLC.pdf
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author Zainal Abidin, Nurul Nadia
author_facet Zainal Abidin, Nurul Nadia
author_sort Zainal Abidin, Nurul Nadia
building UM Research Repository
collection Online Access
description Kalanchoe pinnata is an important plant which has many traditional medicinal uses. In this work, hydroxyproline was extracted from Kalanchoe pinnata. Determination of hydroxyproline in this plant was done using HPLC. Hydroxyproline is one of the element for the formation of collagen. There are three solvent composition used for extraction; 100% of water, 100% of ethanol and 50% of ethanol. It was found that combination of two solvent, ethanol and water can optimize the extraction as when comparing the concentration of hydroxyproline detected in the same extraction time, this system showed the highest concentration of hydroxyproline detected. Another parameter is the duration of maceration time, one to five hours which the time interval between analysis in one hour. The longer the time taken for extraction, the more hydroxyproline extacted from the sample.
first_indexed 2025-11-14T13:35:10Z
format Thesis
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institution University Malaya
institution_category Local University
last_indexed 2025-11-14T13:35:10Z
publishDate 2013
recordtype eprints
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spelling um-57862015-07-28T09:49:59Z Determination of hydroxyproline in Kalanchoe pinnata by HPLC / Nurul Nadia binti Zainal Abidin Zainal Abidin, Nurul Nadia QD Chemistry Kalanchoe pinnata is an important plant which has many traditional medicinal uses. In this work, hydroxyproline was extracted from Kalanchoe pinnata. Determination of hydroxyproline in this plant was done using HPLC. Hydroxyproline is one of the element for the formation of collagen. There are three solvent composition used for extraction; 100% of water, 100% of ethanol and 50% of ethanol. It was found that combination of two solvent, ethanol and water can optimize the extraction as when comparing the concentration of hydroxyproline detected in the same extraction time, this system showed the highest concentration of hydroxyproline detected. Another parameter is the duration of maceration time, one to five hours which the time interval between analysis in one hour. The longer the time taken for extraction, the more hydroxyproline extacted from the sample. 2013 Thesis NonPeerReviewed application/pdf http://studentsrepo.um.edu.my/5786/1/DETERMINATION_OF_HYDROXYPROLINE_IN_KALANCHOE_PINNATA_BY_HPLC.pdf Zainal Abidin, Nurul Nadia (2013) Determination of hydroxyproline in Kalanchoe pinnata by HPLC / Nurul Nadia binti Zainal Abidin. Masters thesis, University of Malaya. http://studentsrepo.um.edu.my/5786/
spellingShingle QD Chemistry
Zainal Abidin, Nurul Nadia
Determination of hydroxyproline in Kalanchoe pinnata by HPLC / Nurul Nadia binti Zainal Abidin
title Determination of hydroxyproline in Kalanchoe pinnata by HPLC / Nurul Nadia binti Zainal Abidin
title_full Determination of hydroxyproline in Kalanchoe pinnata by HPLC / Nurul Nadia binti Zainal Abidin
title_fullStr Determination of hydroxyproline in Kalanchoe pinnata by HPLC / Nurul Nadia binti Zainal Abidin
title_full_unstemmed Determination of hydroxyproline in Kalanchoe pinnata by HPLC / Nurul Nadia binti Zainal Abidin
title_short Determination of hydroxyproline in Kalanchoe pinnata by HPLC / Nurul Nadia binti Zainal Abidin
title_sort determination of hydroxyproline in kalanchoe pinnata by hplc / nurul nadia binti zainal abidin
topic QD Chemistry
url http://studentsrepo.um.edu.my/5786/
http://studentsrepo.um.edu.my/5786/1/DETERMINATION_OF_HYDROXYPROLINE_IN_KALANCHOE_PINNATA_BY_HPLC.pdf