Identification of RB1 germ-line mutations in patients with retinoblastoma / Kavimalar A/P Renganathan
Background: Retinoblastoma (RB1; OMIM#180200) is the most common intraocular tumor in early childhood. The malignancy mainly affects children under five years of age, with a prevalence of 1:15,000 to 1:20,000. RB1 or retinoblastoma susceptibility gene is the gene associated with retinoblastoma and i...
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