Carbogen treatment for pH-stat management in cardiopulmonary bypass / Vijay Sundra Kumuran
Hypocarbia commonly occurs in infants undergoing cardiopulmonary bypass causing respiratory alkalosis with pH-stat management. In this study, pCO2 regulation was adjusted accordingly to sweep gas in control and treatment groups with gas-to-blood flow ratio of 0.5:1. Each extracorporeal membrane o...
| Summary: | Hypocarbia commonly occurs in infants undergoing cardiopulmonary bypass causing
respiratory alkalosis with pH-stat management. In this study, pCO2 regulation was
adjusted accordingly to sweep gas in control and treatment groups with gas-to-blood
flow ratio of 0.5:1. Each extracorporeal membrane oxygenator (Capiox® RX05 and
Medtronic® Minimax Plus® Hollow Fiber Oxygenator) contained control and treatment
groups to determine carbogen intervention is necessary for infants undergoing
hypothermic bypass. Arterial blood gas was corrected according to actual temperature
of the patients for both control (without carbogen) and treatment (with carbogen)
groups. The carbogen treatment was introduced to overcome the problem of maintaining
pH and pCO2 for infants undergoing hypothermic bypass. One hundred and twenty
(120) infants |
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