Synthesis, reaction and structural studies of triorganotin carboxylates / Thong Pui Yee
iiiC6H4CH(Br)CH(OCH3)COOH was obtained as the major product. The triorganotin diorganodithiocarbamylacetate were found to be inert towards any brominating agents. The bromination products were characterized by spectroscopic techniques such as 1H, 13C NMR and FT-IR spectroscopies. The X-ray structure...
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| Format: | Thesis |
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2012
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| Online Access: | http://pendeta.um.edu.my/client/default/search/results?qu=Synthesis%2C+reaction+and+structural+studies+of+triorganotin+carboxylates&te= http://studentsrepo.um.edu.my/3499/4/1._Title_page%2C_abstract%2C_content.pdf http://studentsrepo.um.edu.my/3499/5/2._Chap_1_%E2%80%93_4.pdf http://studentsrepo.um.edu.my/3499/6/3._Appendices.pdf |
| _version_ | 1848772429235617792 |
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| author | Thong Pui, Yee |
| author_facet | Thong Pui, Yee |
| author_sort | Thong Pui, Yee |
| building | UM Research Repository |
| collection | Online Access |
| description | iiiC6H4CH(Br)CH(OCH3)COOH was obtained as the major product. The triorganotin diorganodithiocarbamylacetate were found to be inert towards any brominating agents. The bromination products were characterized by spectroscopic techniques such as 1H, 13C NMR and FT-IR spectroscopies. The X-ray structures of four bromination products namely 2,3-dibromo-3-phenylpropionic acid (A6), 2-bromo-3-methoxy-3-(p-methoxyphenyl)propionic acid (A7), bis(4,4-dimethyl-aminopyridinium)-2,3-dibromo-3-(p-chlorophenyl)propionate (A9) and tricyclohexyltin 2,3-dibromo-3-phenylprionate (P4) were also determined.In addition, ten selected triorganotin carboxylates, C4–C10, C14, P4–P6 were investigated for their cytotoxic activities against the human leukemia HL60 cells. In general, the triorganotin carboxylates exhibit comparable cytotoxic activities to that of cisplatin. |
| first_indexed | 2025-11-14T13:26:22Z |
| format | Thesis |
| id | um-3499 |
| institution | University Malaya |
| institution_category | Local University |
| last_indexed | 2025-11-14T13:26:22Z |
| publishDate | 2012 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | um-34992019-02-19T23:39:24Z Synthesis, reaction and structural studies of triorganotin carboxylates / Thong Pui Yee Thong Pui, Yee QD Chemistry iiiC6H4CH(Br)CH(OCH3)COOH was obtained as the major product. The triorganotin diorganodithiocarbamylacetate were found to be inert towards any brominating agents. The bromination products were characterized by spectroscopic techniques such as 1H, 13C NMR and FT-IR spectroscopies. The X-ray structures of four bromination products namely 2,3-dibromo-3-phenylpropionic acid (A6), 2-bromo-3-methoxy-3-(p-methoxyphenyl)propionic acid (A7), bis(4,4-dimethyl-aminopyridinium)-2,3-dibromo-3-(p-chlorophenyl)propionate (A9) and tricyclohexyltin 2,3-dibromo-3-phenylprionate (P4) were also determined.In addition, ten selected triorganotin carboxylates, C4–C10, C14, P4–P6 were investigated for their cytotoxic activities against the human leukemia HL60 cells. In general, the triorganotin carboxylates exhibit comparable cytotoxic activities to that of cisplatin. 2012-08-08 Thesis NonPeerReviewed application/pdf http://studentsrepo.um.edu.my/3499/4/1._Title_page%2C_abstract%2C_content.pdf application/pdf http://studentsrepo.um.edu.my/3499/5/2._Chap_1_%E2%80%93_4.pdf application/pdf http://studentsrepo.um.edu.my/3499/6/3._Appendices.pdf http://pendeta.um.edu.my/client/default/search/results?qu=Synthesis%2C+reaction+and+structural+studies+of+triorganotin+carboxylates&te= Thong Pui, Yee (2012) Synthesis, reaction and structural studies of triorganotin carboxylates / Thong Pui Yee. Masters thesis, University of Malaya. http://studentsrepo.um.edu.my/3499/ |
| spellingShingle | QD Chemistry Thong Pui, Yee Synthesis, reaction and structural studies of triorganotin carboxylates / Thong Pui Yee |
| title | Synthesis, reaction and structural studies of triorganotin carboxylates / Thong Pui Yee |
| title_full | Synthesis, reaction and structural studies of triorganotin carboxylates / Thong Pui Yee |
| title_fullStr | Synthesis, reaction and structural studies of triorganotin carboxylates / Thong Pui Yee |
| title_full_unstemmed | Synthesis, reaction and structural studies of triorganotin carboxylates / Thong Pui Yee |
| title_short | Synthesis, reaction and structural studies of triorganotin carboxylates / Thong Pui Yee |
| title_sort | synthesis, reaction and structural studies of triorganotin carboxylates / thong pui yee |
| topic | QD Chemistry |
| url | http://pendeta.um.edu.my/client/default/search/results?qu=Synthesis%2C+reaction+and+structural+studies+of+triorganotin+carboxylates&te= http://pendeta.um.edu.my/client/default/search/results?qu=Synthesis%2C+reaction+and+structural+studies+of+triorganotin+carboxylates&te= http://studentsrepo.um.edu.my/3499/4/1._Title_page%2C_abstract%2C_content.pdf http://studentsrepo.um.edu.my/3499/5/2._Chap_1_%E2%80%93_4.pdf http://studentsrepo.um.edu.my/3499/6/3._Appendices.pdf |