Isolation and identification of cyclic polyketides from Endiandra kingiana gamble (lauraceae), as BCL-XL/BAK and MCL-1/BID dual inhibitors, and approaches toward the synthesis of kingianins / Mohamad Nurul Azmi Mohamad Taib

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Isolation and identification of cyclic polyketides from Endiandra kingiana gamble (lauraceae), as BCL-XL/BAK and MCL-1/BID dual inhibitors, and approaches toward the synthesis of kingianins / Mohamad Nurul Azmi Mohamad Taib

The preliminary screening showed that the bark of Endiandra kingiana Gamble exhibited potency as a modulating agent between Bcl-xL and Bak, which prompted its chemical investigation. Two groups of compounds were isolated and characterized; the endiandric acid series and the kingianin series. Eigh...

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Bibliographic Details
Main Author:	Mohamad Nurul Azmi , Mohamad Taib
Format:	Thesis
Published:	2015
Subjects:	Q Science (General) QD Chemistry
Online Access:	http://studentsrepo.um.edu.my/14661/ http://studentsrepo.um.edu.my/14661/1/Mohamad_Nurul_Azmi.pdf

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