Synthesis of new anilinoquinazoline derivatives as potential anticancer agents: Antiproliferative activity, molecular docking and molecular dynamics studies / Muhammad Kumayl Abdul Wahab

QR Code

Synthesis of new anilinoquinazoline derivatives as potential anticancer agents: Antiproliferative activity, molecular docking and molecular dynamics studies / Muhammad Kumayl Abdul Wahab

Current reversible epidermal growth factor (EGFR) tyrosine kinase inhibitors of the non-small cell lung cancer (NSCLC) have been resisted by T790M mutation, while irreversible inhibitors introduced to overcome the mutation have faced resistance from C797S mutation. In the effort to discover potentia...

Full description

Bibliographic Details
Main Author:	Muhammad Kumayl , Abdul Wahab
Format:	Thesis
Published:	2021
Subjects:	Q Science (General) QD Chemistry
Online Access:	http://studentsrepo.um.edu.my/12959/ http://studentsrepo.um.edu.my/12959/2/Muhammad_Kumayl.pdf http://studentsrepo.um.edu.my/12959/1/Muhammad_Kumayl.pdf

Similar Items

Cytotoxicity, antimutagenicity and molecular docking of benzimidazole derivatives as anticancer agents
by: Azahar, Nurul Hafizan
Published: (2021)

Molecular docking of substituted schiff bases derived from s-benzyldithiocarbazate as potential anticancer agents
by: How, Fiona Ni Foong
Published: (2018)

Molecular docking
by: Abduallah Alsafi, Hassen Mohammed, et al.
Published: (2011)

Cholinesterase inhibition activity and molecular docking study of eugenol derivatives
by: Khairunisa Mohd Zamli,, et al.
Published: (2021)

Synthesis and molecular docking of 2, 4, 5-trisubstituted-1,3-thiazole derivatives as antibacterial agents
by: Abdullah Ripain, Iswatun Hasanah, et al.
Published: (2018)

Synthesis, neuraminidase inhibition assay and molecular docking of carvone derivatives
by: Abd Hamid, Shafida
Published: (2019)

Molecular docking analysis of Carica papaya Linn constituents as antiviral agent
by: Narayanaswamy, Radhakrishnan, et al.
Published: (2017)

Synthesis and molecular docking of carvone derivatives as a potential neuraminidase inhibitors
by: Jusoh, Noorakmar, et al.
Published: (2016)

Baicalein as promising anticancer agent_A comprehensive analysis on molecular mechanisms
by: Morshed, A K M Helal, et al.
Published: (2023)

Synthesis of thymidine phosphorylase inhibitor based on quinoxaline derivatives and their molecular docking study
by: Noor Barak, Almandil, et al.
Published: (2019)

Synthesis of thymidine phosphorylase inhibitor based on quinoxaline derivatives and their molecular docking study
by: Almandil, Noor Barak, et al.
Published: (2019)

Potent halogenated xanthone derivatives: synthesis, molecular docking and study on antityrosinase activity
by: Baharuddin, Fatin Farhana, et al.
Published: (2023)

Synthesis, Characterisation And Molecular Docking Of Quinoxaline-isoxazole Hybrids As Potential Anti-hyperglycemic Agent
by: Phongphane, Lacksany
Published: (2024)

Molecular Docking And Molecular Dynamics Of 3-O-Octanoylcatechin Interactions Against Aldose Reductase
by: Soib’, Shikin Faezah
Published: (2019)

Synthesis, characterization and molecular docking of hydroxyxanthone and renylated xanthone derivatives as potential aromatase inhibitor
by: Ramakrishnan, Shurutishria
Published: (2022)

Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure
by: Dohle, W., et al.
Published: (2018)

Molecular Docking Of Andrographolide To Rennin, HIV-Protease And Tyrosine Enzymes.
by: Kamaluddin, Achsanuddin, et al.
Published: (2003)

Baicalein as promising anticancer agent: A comprehensive analysis on molecular mechanisms and therapeutic perspectives
by: Morshed, A. K.M.Helal, et al.
Published: (2023)

Andrographolide as a template in the synthesis of new anticancer agents with potentially novel molecular targets
by: Stanslas, Johnson, et al.
Published: (2010)

Molecular docking and molecular dynamic simulation of 1,3-Benzoxazine derivatives against penicillin binding protein 2A of methicillin-resistant Staphlyococcus aureus
by: Alharbi, Nourah Jamaan H
Published: (2023)

Design, Synthesis, Molecular Docking And Cytotoxic Activity Of New Ortho-Hydroxy Chalcone And Pyrazoline Derivatives
by: Luhaibi, Maadh Jumaah Owaid
Published: (2019)

Synthesis, Cholinesterase Inhibitory Activity And Molecular Docking Study Of Piperidone-Grafted Pyrimidine And Thiazolopyrimidine Derivatives
by: Basiri, Alireza
Published: (2014)

Latest developments in molecular docking: 2010-2011 in review
by: Yuriev, E., et al.
Published: (2013)

Docking And Molecular Dynamics Simulation Studies Of Insulin-Β-Cyclodextrin Interactions
by: Muhammad, Erma Fatiha
Published: (2016)

Docking And Molecular Dynamics Simulation Studies Of Insulin-P- Cyclodextrin Interactions
by: Muhammad, Erma Fatiha
Published: (2016)

Glycerol and biodiesel recovery from palm oil derived from used fried chicken cooking oil / Muhammad Hafiz Abdul Wahab
by: Abdul Wahab, Muhammad Hafiz
Published: (2018)

Prospects of compounds of herbal plants as anticancer agents: a comprehensive review from molecular pathways
by: Situmorang, Putri Cahaya, et al.
Published: (2024)

Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study
by: Zaman, Khalid, et al.
Published: (2019)

Elucidating the binding affinity of meso porphyrin derivatives with Bcl-2 through synthesis and molecular docking analysis
by: Yasothaa Ramaiyah,, et al.
Published: (2023)

Design, Synthesis and Molecular Docking Studies of Some Novel Spiro Derivatives By 1,3-Cycloaddition Reaction
by: Hasmaruddin, Nurul Syazana, et al.
Published: (2016)

Evaluation of potential bacterial protease inhibitor properties of selected hydroxyquinoline derivatives : An in silico docking and molecular dynamics simulation approach
by: Riaz, Faiza, et al.
Published: (2023)

The study of heat treatment activities in Malaysia / Muhammad Noor Harun and Hisham Abdul Wahab
by: Harun, Muhammad Noor, et al.
Published: (1994)

Synthesis, molecular docking and heme detoxification of pyrano[2,3-c]pyrazoleaminoquinoline hybrids as potential antimalarial agents
by: Lekkala Ravindar,, et al.
Published: (2024)

Molecular docking and in silico evaluation of phytochemicals of bioactive methanolic extract of Ipomoea mauritiana Jacq. as anti-bacterial agents
by: Roney, Miah, et al.
Published: (2022)

Docking and molecular dynamics simulations of the ternary complex nisin2:lipid II
by: Mulholland, Sam, et al.
Published: (2016)

A quest on finding new potential ebola vp40 inhibitors: molecular docking and molecular dynamics simulation studies
by: Mohamad Yussoff, Mohamad Ariff, et al.
Published: (2018)

Investigating the potential compounds of Kalanchoe pinnata plant for the treatment of inflammation utilizing molecular docking and molecular dynamic simulation approach
by: Hamim, S. M. I., et al.
Published: (2025)

Study of the antidiabetic mechanism of berberine compound on FOXO1 transcription factor through molecular docking and molecular dynamics simulations
by: Maksum, Iman Permana, et al.
Published: (2024)

Molecular docking of Cellobiose and Cellotetraose into an Endoglucanase from Fusarium oxysporum
by: Ibrahim Ali , Noorbatcha, et al.
Published: (2013)

Molecular docking of cellobiose and cellotetraose into an endoglucanase from fusarium oxysporum
by: Ibrahim Ali, Noorbatcha, et al.
Published: (2014)