Antimycotic activity of the extracts of stichopus chloronotus brandt in the treatment of experimental dermatophytosis
The aqueous and ethanol extracts of Stichopus chloronotus Brandt were investigated for their effectiveness against guinea pig dermatophytosis caused by Microsporum canis and Trichophyton mentagrophytes using the hair root invasion test. The ethanol extract at 10 mg/ml showed 82.8 % efficacy against...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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penerbit ukm
2004
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| Online Access: | http://journalarticle.ukm.my/971/ http://journalarticle.ukm.my/971/1/jurnal26.pdf |
| _version_ | 1848809373070000128 |
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| author | Dayang Fredalina Basri, Jacinta S., Chong S.L, Rohasmizah Ismail, |
| author_facet | Dayang Fredalina Basri, Jacinta S., Chong S.L, Rohasmizah Ismail, |
| author_sort | Dayang Fredalina Basri, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | The aqueous and ethanol extracts of Stichopus chloronotus Brandt were investigated for their effectiveness against guinea pig dermatophytosis caused by Microsporum canis and Trichophyton mentagrophytes using the hair root invasion test. The ethanol extract at 10 mg/ml showed 82.8 %
efficacy against T. mentagrophytes while the aqueous extract at similar concentration showed 84.8% efficacy against M. canis infection, as compared to econazole which showed 100% efficacy against both infections. No adverse effect on the skin was observed in the treated animals. In conclusion, aqueous and ethanol extracts of S. chloronotus showed high antimycotic activity against experimentally induced dermatophytosis in guinea pigs. |
| first_indexed | 2025-11-14T23:13:34Z |
| format | Article |
| id | ukm-971 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T23:13:34Z |
| publishDate | 2004 |
| publisher | penerbit ukm |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ukm-9712016-12-14T06:28:27Z http://journalarticle.ukm.my/971/ Antimycotic activity of the extracts of stichopus chloronotus brandt in the treatment of experimental dermatophytosis Dayang Fredalina Basri, Jacinta S., Chong S.L, Rohasmizah Ismail, The aqueous and ethanol extracts of Stichopus chloronotus Brandt were investigated for their effectiveness against guinea pig dermatophytosis caused by Microsporum canis and Trichophyton mentagrophytes using the hair root invasion test. The ethanol extract at 10 mg/ml showed 82.8 % efficacy against T. mentagrophytes while the aqueous extract at similar concentration showed 84.8% efficacy against M. canis infection, as compared to econazole which showed 100% efficacy against both infections. No adverse effect on the skin was observed in the treated animals. In conclusion, aqueous and ethanol extracts of S. chloronotus showed high antimycotic activity against experimentally induced dermatophytosis in guinea pigs. penerbit ukm 2004 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/971/1/jurnal26.pdf Dayang Fredalina Basri, and Jacinta S., and Chong S.L, and Rohasmizah Ismail, (2004) Antimycotic activity of the extracts of stichopus chloronotus brandt in the treatment of experimental dermatophytosis. Jurnal Sains Kesihatan Malaysia, 2 (2). pp. 97-102. ISSN 1675-8161 http://www.fskb.ukm.my/fskbold/jurnal |
| spellingShingle | Dayang Fredalina Basri, Jacinta S., Chong S.L, Rohasmizah Ismail, Antimycotic activity of the extracts of stichopus chloronotus brandt in the treatment of experimental dermatophytosis |
| title | Antimycotic activity of the extracts of stichopus chloronotus brandt in the treatment of experimental dermatophytosis |
| title_full | Antimycotic activity of the extracts of stichopus chloronotus brandt in the treatment of experimental dermatophytosis |
| title_fullStr | Antimycotic activity of the extracts of stichopus chloronotus brandt in the treatment of experimental dermatophytosis |
| title_full_unstemmed | Antimycotic activity of the extracts of stichopus chloronotus brandt in the treatment of experimental dermatophytosis |
| title_short | Antimycotic activity of the extracts of stichopus chloronotus brandt in the treatment of experimental dermatophytosis |
| title_sort | antimycotic activity of the extracts of stichopus chloronotus brandt in the treatment of experimental dermatophytosis |
| url | http://journalarticle.ukm.my/971/ http://journalarticle.ukm.my/971/ http://journalarticle.ukm.my/971/1/jurnal26.pdf |