Biological activities of four Melicope Species
The leaves and stem barks extracts of four plant species, Melicope confusa, M. clemensiae, M. lunu-ankenda and M. latifolia were screened for their antimicrobial, antioxidant and cytotoxic activities. Almost all extracts of M. clemensia exhibited moderate growth inhibition when tested against the t...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universiti Kebangsaan Malaysia
2009
|
| Online Access: | http://journalarticle.ukm.my/7/ http://journalarticle.ukm.my/7/1/ |
| _version_ | 1848809134367965184 |
|---|---|
| author | Najihah moh Hashim, Mawardi Rahmani, Hazar Bebe Mohd Ismail, Mohd Aspollah Sukari, Manaf Ali .A, Ee Cheng Lian, Gwendoline |
| author_facet | Najihah moh Hashim, Mawardi Rahmani, Hazar Bebe Mohd Ismail, Mohd Aspollah Sukari, Manaf Ali .A, Ee Cheng Lian, Gwendoline |
| author_sort | Najihah moh Hashim, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | The leaves and stem barks extracts of four plant species, Melicope confusa, M. clemensiae, M. lunu-ankenda and M.
latifolia were screened for their antimicrobial, antioxidant and cytotoxic activities. Almost all extracts of M. clemensia exhibited moderate growth inhibition when tested against the three pathogenic fungi. However, when tested against pathogenic bacteria, the three leaves extracts showed strong activity against methicillin resistant S. aureus and moderate for the other bacteria. In the antioxidant assay by using DPPH, the three leaves extracts of M. lunu-ankenda exhibited significant activity with with IC50 values of 7.8, 15.6 and 7.8 μg/mL. In addition, the petroleum ether leaves extract of M.
clemensiae and the chloroform leaves extract of M. lunu-ankenda showed strong cytotoxic activity when tested against human promyelocytic leukemia (HL60) cell line with IC50 values of 2.8 and 0.8 μg/mL, respectively. |
| first_indexed | 2025-11-14T23:09:47Z |
| format | Article |
| id | ukm-7 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T23:09:47Z |
| publishDate | 2009 |
| publisher | Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ukm-72016-12-14T06:26:10Z http://journalarticle.ukm.my/7/ Biological activities of four Melicope Species Najihah moh Hashim, Mawardi Rahmani, Hazar Bebe Mohd Ismail, Mohd Aspollah Sukari, Manaf Ali .A, Ee Cheng Lian, Gwendoline The leaves and stem barks extracts of four plant species, Melicope confusa, M. clemensiae, M. lunu-ankenda and M. latifolia were screened for their antimicrobial, antioxidant and cytotoxic activities. Almost all extracts of M. clemensia exhibited moderate growth inhibition when tested against the three pathogenic fungi. However, when tested against pathogenic bacteria, the three leaves extracts showed strong activity against methicillin resistant S. aureus and moderate for the other bacteria. In the antioxidant assay by using DPPH, the three leaves extracts of M. lunu-ankenda exhibited significant activity with with IC50 values of 7.8, 15.6 and 7.8 μg/mL. In addition, the petroleum ether leaves extract of M. clemensiae and the chloroform leaves extract of M. lunu-ankenda showed strong cytotoxic activity when tested against human promyelocytic leukemia (HL60) cell line with IC50 values of 2.8 and 0.8 μg/mL, respectively. Universiti Kebangsaan Malaysia 2009-10 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/7/1/ Najihah moh Hashim, and Mawardi Rahmani, and Hazar Bebe Mohd Ismail, and Mohd Aspollah Sukari, and Manaf Ali .A, and Ee Cheng Lian, Gwendoline (2009) Biological activities of four Melicope Species. Sains Malaysiana, 38 (5). pp. 767-771. ISSN 0126-6039 http://www.ukm.my/~jsm/kandungan.html |
| spellingShingle | Najihah moh Hashim, Mawardi Rahmani, Hazar Bebe Mohd Ismail, Mohd Aspollah Sukari, Manaf Ali .A, Ee Cheng Lian, Gwendoline Biological activities of four Melicope Species |
| title | Biological activities of four Melicope Species |
| title_full | Biological activities of four Melicope Species |
| title_fullStr | Biological activities of four Melicope Species |
| title_full_unstemmed | Biological activities of four Melicope Species |
| title_short | Biological activities of four Melicope Species |
| title_sort | biological activities of four melicope species |
| url | http://journalarticle.ukm.my/7/ http://journalarticle.ukm.my/7/ http://journalarticle.ukm.my/7/1/ |