Role of ABCB1 C3435T variant in response to antiepileptic drugs in epilepsy: a review

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Role of ABCB1 C3435T variant in response to antiepileptic drugs in epilepsy: a review

Over-expression of P-glycoprotein (P-gp), the encoded product of the ATP-binding cassette (ABC), sub-family B, member 1 (ABCB1/MDR1) gene, plays an important role in mediating multidrug resistance to antiepileptic drugs (AEDs) in about 30% of patients with epilepsy. Genetic variation may in part exp...

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Bibliographic Details
Main Authors:	Haerian BS, Mohamed Z, Mohamed EHM, Lim KS, Tan HJ, Tan CT, Raymond AA
Format:	Article
Language:	English
Published:	Penerbit UKM 2009
Online Access:	http://journalarticle.ukm.my/1938/ http://journalarticle.ukm.my/1938/1/04-4%282%29_~_MS_085_%2864-75%29.pdf

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