Detection of BCR/ABL gene in chronic Myeloid Leukaemia: comparison of Fluorescence in situ Hybridisation (FISH), conventional Cytogenetics and Polymerase Chain Reaction (PCR) techniques

QR Code

Detection of BCR/ABL gene in chronic Myeloid Leukaemia: comparison of Fluorescence in situ Hybridisation (FISH), conventional Cytogenetics and Polymerase Chain Reaction (PCR) techniques

The reciprocal translocation t(9;22)(q34;q11) which gives rise to the Philadelphia (Ph1) chromosome and BCR/ABL fusion gene, plays a pivotal role in the diagnosis and pathogenesis of chronic myeloid leukemia (CML). In this study, we evaluated the role of fluorescence in situ hybridisation (FISH) in...

Full description

Bibliographic Details
Main Authors:	Reena RMZ, Julia Munchar MJ, Salwati S, Hamidah NH, Zubaidah Z, Sharifah NA, Cheong SK
Format:	Article
Language:	English
Published:	Penerbit UKM 2006
Online Access:	http://journalarticle.ukm.my/1829/ http://journalarticle.ukm.my/1829/1/02._5-13_%28MH_006%29.pdf

Similar Items

Detection of BCR-ABL T315i mutation in imatinib resistant chronic myeloid leukemia patients
by: Mardziah M,, et al.
Published: (2019)

Donor chimerism and bcr-abl gene status following non-myeloablative peripheral blood stem cell transplantation in chronic myeloid leukaemia patients in HUKM
by: Seman, Zainina, et al.
Published: (2008)

Aleukemic bcr-abl positive granulocytic sarcoma
by: Kuan, Jew-Win, et al.
Published: (2009)

Contribution of BCR-ABL kinase domain mutations to imatinib mesylate resistance in Philadelphia chromosome positive Malaysian chronic myeloid leukemia patients
by: Elias, Marjanu Hikmah, et al.
Published: (2012)

The prognostic impact of CD7 expression of leukaemic blasts in de novo intermediate cytogenetic risk acute myeloid leukaemia.
by: Kesavan, M., et al.
Published: (2016)

Concomitant BCR-ABL and JAK2 V617F in a patient with myeloproliferative neoplasm: a case report
by: A, Alia Suzana, et al.
Published: (2023)

Genetic determinants excluding GBCR::ABL mutations of imatinib mesylate therapy response among chronic myeloid leukaemia patients in Malaysia
by: Ismail, Siti Mariam
Published: (2023)

Targeting dormancy in acute myeloid leukaemia
by: Doolan, Lara
Published: (2023)

ENPP4 and HOXA3 as potential leukaemia stem cell markers in acute myeloid leukaemia
by: Mohd Amin, A, et al.
Published: (2023)

Identification of Y chromosomal material in turner syndrome by Fluorescence in Situ Hybridisation (FISH)
by: Reena Rahayu Md Zin,, et al.
Published: (2008)

Identifying and targeting dormant cells in acute myeloid leukaemia
by: Yu, N.
Published: (2016)

Less utilized prognostic markers in acute myeloid leukaemia
by: Abdullah, Maha
Published: (2016)

Recent advances in diagnosis of acute myeloid leukaemia : a review.
by: Ambayya, Angeli, et al.
Published: (2013)

Proteomic profile of acute myeloid leukaemia: a review update
by: Almaiman, Amer Abdulrahman, et al.
Published: (2016)

Identification of differentially expressed proteins as biomarkers of acute myeloid leukaemia
by: Barantalab, Fatemeh
Published: (2014)

Selection of reference genes for quantitative studies in acute myeloid leukaemia
by: Lee, Cindee, et al.
Published: (2019)

Disease acceptance and adherence to imatinib in Taiwanese chronic myeloid leukaemia outpatients
by: Chen, Li-Chia, et al.
Published: (2014)

The role of conventional and molecular cytogenetics in the diagnosis of microdeletion syndromes
by: Salwati Shuib,, et al.
Published: (2006)

Activity of the aurora kinase B inhibitor AZD1152 in acute myeloid leukaemia
by: Grundy, Martin
Published: (2012)

Cell viability of acute myeloid leukaemia blasts in culture correlates with treatment outcome
by: Abdullah, Maha, et al.
Published: (2008)

Plasma and cell lysate proteins associated with treatment outcome in acute myeloid leukaemia
by: Barantalab, Fatemeh, et al.
Published: (2020)

Gene aberrations and methylation analysis of JAK/stat and toll-like receptor downstream signalling in BCR-ABL-negative myeloproliferative neoplasms and myelodysplastic syndrome/myeloproliferative neoplasms overlap syndromes
by: Cai, Chia Yuh
Published: (2021)

Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells
by: Pallis, Monica, et al.
Published: (2013)

Investigation of dormancy in acute myeloid leukaemia cells and the induction of dormancy in their response to genotoxic stress
by: Al-Asadi, Mazin Gh.
Published: (2017)

Arginine dependence of acute myeloid leukaemia blast proliferation: a novel therapeutic target
by: Mussai, Francis, et al.
Published: (2015)

Utilization of chemotherapy regimen for acute myeloid leukaemia patients in Ampang Hospital / Jamaliah Jamari
by: Jamari, Jamaliah
Published: (2015)

The cytotoxicity effect of ant-444 in human chronic myeloid leukaemia cells (K 562)
by: Khalid, Nor Bahijah, et al.
Published: (2013)

Incidence of c-Cbl mutations in human acute myeloid leukaemias in an Australian patient cohort
by: Ghassemifar, Reza, et al.
Published: (2011)

Efficacy of dendritic cell-based vaccine on acute myeloid leukaemia in a murine model
by: Ng, Wei Yi
Published: (2013)

Evaluating a rapid method to quantify multiple gene expression in acute myeloid leukaemia
by: Lee, Cin Dee
Published: (2013)

Cockle shell-derived nano carrier for Ara-C in the treatment of acute myeloid leukaemia
by: Ghaji, Mustafa Saddam
Published: (2018)

Gene Expression Profile And Modulation Of Genetic Pathways In Acute Myeloid Leukaemia T(8;21)
by: Bashanfer, Salem Ali Alsalem
Published: (2013)

Expression of survival and apoptotic molecules in response to early stage chemotherapy in acute myeloid leukaemia
by: Yiau, Stephnie Kang Xian
Published: (2013)

A molecular signature of dormancy in CD34+CD38- acute myeloid leukaemia cells
by: Al-Asadi, Mazin Gh., et al.
Published: (2017)

Infantile acute megakaryoblastic leukaemia with T(1:22) in a non-down syndrome child.
by: Nurasyikin Y,, et al.
Published: (2012)

Development of an Interspecific Hybridisation Protocol for Lupinus
by: Easton, Julia, et al.
Published: (2008)

DNA damage response and anti-apoptotic proteins expression in NPMc+ mutated cells in acute myeloid leukaemia
by: Qutob, Haitham
Published: (2014)

FLT3, NPM1, DNMT3a and NRAS genes mutation in acute myeloid leukaemia in HUSM
by: Mat Yunus, Noraini
Published: (2015)

The Clinical Significance Of Npm1, Flt3 And Cebpa Gene Mutations In Adult Patients With Acute Myeloid Leukaemia
by: Ul Haq, Izaz
Published: (2020)

Elucidating the genomic and transcriptomic profiles contributing to the overall survival of acute myeloid leukaemia patients with normal karyotype in Malaysia
by: Ambayya @ Ampiah, A Angeli
Published: (2024)