Empirical correlations for pressure drop across A chromatographic bed packed with A compressible packing

Experiments were done to obtain a correlation between pressure drop across a chromatographic bed packed with a compressible packing, Sephadex G100, and other measurable parameters such as flowrate, column length and diameter, particle size, and permeability. The pressure drop across the bed is ob...

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Main Author: Abdul Wahab Mohammad
Format: Article
Published: 1993
Online Access:http://journalarticle.ukm.my/1305/
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author Abdul Wahab Mohammad,
author_facet Abdul Wahab Mohammad,
author_sort Abdul Wahab Mohammad,
building UKM Institutional Repository
collection Online Access
description Experiments were done to obtain a correlation between pressure drop across a chromatographic bed packed with a compressible packing, Sephadex G100, and other measurable parameters such as flowrate, column length and diameter, particle size, and permeability. The pressure drop across the bed is obtained by subtracting the extracolumn pressure drop from the operating pressure drop. It was found that the pressure drop increased nonlinearly as the flowrate increased. There is a critical flowrate after which the pressure drop increases infinitely. The pressure drop was also found to be dependent on the column diameter within the range tested. The data were fitted well with an equation similar to the Blake-Kozeny equation but with an exponential term and a critical factor included
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institution Universiti Kebangasaan Malaysia
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spelling ukm-13052011-10-11T03:45:17Z http://journalarticle.ukm.my/1305/ Empirical correlations for pressure drop across A chromatographic bed packed with A compressible packing Abdul Wahab Mohammad, Experiments were done to obtain a correlation between pressure drop across a chromatographic bed packed with a compressible packing, Sephadex G100, and other measurable parameters such as flowrate, column length and diameter, particle size, and permeability. The pressure drop across the bed is obtained by subtracting the extracolumn pressure drop from the operating pressure drop. It was found that the pressure drop increased nonlinearly as the flowrate increased. There is a critical flowrate after which the pressure drop increases infinitely. The pressure drop was also found to be dependent on the column diameter within the range tested. The data were fitted well with an equation similar to the Blake-Kozeny equation but with an exponential term and a critical factor included 1993 Article PeerReviewed Abdul Wahab Mohammad, (1993) Empirical correlations for pressure drop across A chromatographic bed packed with A compressible packing. Jurnal Kejuruteraan, 5 . http://www.ukm.my/jkukm/index.php/jkukm
spellingShingle Abdul Wahab Mohammad,
Empirical correlations for pressure drop across A chromatographic bed packed with A compressible packing
title Empirical correlations for pressure drop across A chromatographic bed packed with A compressible packing
title_full Empirical correlations for pressure drop across A chromatographic bed packed with A compressible packing
title_fullStr Empirical correlations for pressure drop across A chromatographic bed packed with A compressible packing
title_full_unstemmed Empirical correlations for pressure drop across A chromatographic bed packed with A compressible packing
title_short Empirical correlations for pressure drop across A chromatographic bed packed with A compressible packing
title_sort empirical correlations for pressure drop across a chromatographic bed packed with a compressible packing
url http://journalarticle.ukm.my/1305/
http://journalarticle.ukm.my/1305/