Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts
Two species of plants, Andrographis paniculata and Euphorbia hirta were screened for antibacterial activities against three Gram positives and Gram negatives. The leaves from both plants were extracted by methanol extraction. The antibacterial activity was detected with spread plate well diffusion m...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Penerbit UKM
2007
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| Online Access: | http://journalarticle.ukm.my/1096/ http://journalarticle.ukm.my/1096/1/jurnal76.pdf |
| _version_ | 1848809411769794560 |
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| author | Ahmad Zorin Sahalan, Nazahiyah Sulaiman, Nihayah Mohammed, Kaswandi Md. Ambia, Hing, Hian Lian |
| author_facet | Ahmad Zorin Sahalan, Nazahiyah Sulaiman, Nihayah Mohammed, Kaswandi Md. Ambia, Hing, Hian Lian |
| author_sort | Ahmad Zorin Sahalan, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Two species of plants, Andrographis paniculata and Euphorbia hirta were screened for antibacterial activities against three Gram positives and Gram negatives. The leaves from both plants were extracted by methanol extraction. The antibacterial activity was detected with spread plate well diffusion method. The extracts of both plants demonstrated inhibitory activity against both Gram negatives and positives bacteria. Staphylococcus aureus, Bacillus subtilis, Streptococcus epidemidis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. The minimum inhibitory concentration (MIC) determination using micro dilution method showed that the MIC of A. paniculata for the tested bacteria were 1.56mg/ml (Staph. aureus), 3.13mg/ml (BAcillus subtilis), 3.13mg/ml (Strept. epidemidis), 1.56mg/ml (Escherichia coli), 12.50mg/ml (Klebsiella pneumoniae) and 3.13mg/ml (Pseudomonas aeruginosa)respectively. The MIC value for E. hirta was 6.25mg/ml (Staph. aureus) and 3.13mg/ml (BAcillus subtilis), 3.13mg/ml (Strept.Epidemidis), 3.13mg/ml (Psedomonas aeruginosa), 12.5mg/ml (Escherichia coli), and 6.25mg/ml (Klebsiella pneumoniae). Both plants represent a potential for pharmaceutical and agricultural applications and are worthy of further study. |
| first_indexed | 2025-11-14T23:14:11Z |
| format | Article |
| id | ukm-1096 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T23:14:11Z |
| publishDate | 2007 |
| publisher | Penerbit UKM |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ukm-10962016-12-14T06:28:48Z http://journalarticle.ukm.my/1096/ Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts Ahmad Zorin Sahalan, Nazahiyah Sulaiman, Nihayah Mohammed, Kaswandi Md. Ambia, Hing, Hian Lian Two species of plants, Andrographis paniculata and Euphorbia hirta were screened for antibacterial activities against three Gram positives and Gram negatives. The leaves from both plants were extracted by methanol extraction. The antibacterial activity was detected with spread plate well diffusion method. The extracts of both plants demonstrated inhibitory activity against both Gram negatives and positives bacteria. Staphylococcus aureus, Bacillus subtilis, Streptococcus epidemidis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. The minimum inhibitory concentration (MIC) determination using micro dilution method showed that the MIC of A. paniculata for the tested bacteria were 1.56mg/ml (Staph. aureus), 3.13mg/ml (BAcillus subtilis), 3.13mg/ml (Strept. epidemidis), 1.56mg/ml (Escherichia coli), 12.50mg/ml (Klebsiella pneumoniae) and 3.13mg/ml (Pseudomonas aeruginosa)respectively. The MIC value for E. hirta was 6.25mg/ml (Staph. aureus) and 3.13mg/ml (BAcillus subtilis), 3.13mg/ml (Strept.Epidemidis), 3.13mg/ml (Psedomonas aeruginosa), 12.5mg/ml (Escherichia coli), and 6.25mg/ml (Klebsiella pneumoniae). Both plants represent a potential for pharmaceutical and agricultural applications and are worthy of further study. Penerbit UKM 2007 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/1096/1/jurnal76.pdf Ahmad Zorin Sahalan, and Nazahiyah Sulaiman, and Nihayah Mohammed, and Kaswandi Md. Ambia, and Hing, Hian Lian (2007) Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts. Jurnal Sains Kesihatan Malaysia, 5 (2). pp. 1-8. ISSN 1675-8161 http://www.fskb.ukm.my/fskbold |
| spellingShingle | Ahmad Zorin Sahalan, Nazahiyah Sulaiman, Nihayah Mohammed, Kaswandi Md. Ambia, Hing, Hian Lian Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts |
| title | Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts |
| title_full | Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts |
| title_fullStr | Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts |
| title_full_unstemmed | Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts |
| title_short | Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts |
| title_sort | antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts |
| url | http://journalarticle.ukm.my/1096/ http://journalarticle.ukm.my/1096/ http://journalarticle.ukm.my/1096/1/jurnal76.pdf |