The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects
Physical training is associated with axidative stress and improvement in blood antioxidant status. In this study, we investigated the effects of training on plasma malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) as markers of lipid peroxidation, superoxide dismutase (SOD) activity, and ascorbic a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
penerbit ukm
2007
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| Online Access: | http://journalarticle.ukm.my/1092/ http://journalarticle.ukm.my/1092/1/jurnal72.pdf |
| _version_ | 1848809410521989120 |
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| author | Farah Fauzi, Siti Balkis Budin, Shahrul Azwan, Leong, Kok Yuen |
| author_facet | Farah Fauzi, Siti Balkis Budin, Shahrul Azwan, Leong, Kok Yuen |
| author_sort | Farah Fauzi, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Physical training is associated with axidative stress and improvement in blood antioxidant status. In this study, we investigated the effects of training on plasma malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) as markers of lipid peroxidation, superoxide dismutase (SOD) activity, and ascorbic acid (AA) after a single bout of acute exercise. Twelve healthy, untrained young adult men were recruited for 5 weeks of aerobic training period. They were subjected to a rope-skipping exercise for 20 minutes at the intensity of 65 – 80% of heart rate reserve, thrice weekly. They also had to perform a single, acute bout of the same exercise protocol prior to and after training period. Venous blood samples were collected at resting condition (BL), immediately (0 h) and 24 hours (24 h) post acute exercise on both single bout sessions. Results showed that the pattern changes of oxidative stress response are quite similar on both acute sessions. The acute bouts of rope-skipping is associated with a significant increased (p= 0.001) in lipid peroxidation markers immediately after cessation of exercise, with a concomitant increase in antioxidant levels, albeit higher when compared to pre-training values (p = 0.001). These changes were followed by a significant decreased (p = 0.001) in all parameters, toward resting values, 24 hours thereafter. The training program seemed to induce a significant increase in MDA and 4-HNE but also enhanced the antioxidant defense system namely SOD and AA among the untrained subjects. |
| first_indexed | 2025-11-14T23:14:10Z |
| format | Article |
| id | ukm-1092 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T23:14:10Z |
| publishDate | 2007 |
| publisher | penerbit ukm |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | ukm-10922016-12-14T06:28:47Z http://journalarticle.ukm.my/1092/ The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects Farah Fauzi, Siti Balkis Budin, Shahrul Azwan, Leong, Kok Yuen Physical training is associated with axidative stress and improvement in blood antioxidant status. In this study, we investigated the effects of training on plasma malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) as markers of lipid peroxidation, superoxide dismutase (SOD) activity, and ascorbic acid (AA) after a single bout of acute exercise. Twelve healthy, untrained young adult men were recruited for 5 weeks of aerobic training period. They were subjected to a rope-skipping exercise for 20 minutes at the intensity of 65 – 80% of heart rate reserve, thrice weekly. They also had to perform a single, acute bout of the same exercise protocol prior to and after training period. Venous blood samples were collected at resting condition (BL), immediately (0 h) and 24 hours (24 h) post acute exercise on both single bout sessions. Results showed that the pattern changes of oxidative stress response are quite similar on both acute sessions. The acute bouts of rope-skipping is associated with a significant increased (p= 0.001) in lipid peroxidation markers immediately after cessation of exercise, with a concomitant increase in antioxidant levels, albeit higher when compared to pre-training values (p = 0.001). These changes were followed by a significant decreased (p = 0.001) in all parameters, toward resting values, 24 hours thereafter. The training program seemed to induce a significant increase in MDA and 4-HNE but also enhanced the antioxidant defense system namely SOD and AA among the untrained subjects. penerbit ukm 2007 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/1092/1/jurnal72.pdf Farah Fauzi, and Siti Balkis Budin, and Shahrul Azwan, and Leong, Kok Yuen (2007) The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects. Jurnal Sains Kesihatan Malaysia, 5 (2). pp. 39-52. ISSN 1675-8161 http://www.fskb.ukm.my/fskbold |
| spellingShingle | Farah Fauzi, Siti Balkis Budin, Shahrul Azwan, Leong, Kok Yuen The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects |
| title | The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects |
| title_full | The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects |
| title_fullStr | The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects |
| title_full_unstemmed | The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects |
| title_short | The effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects |
| title_sort | effect of 5-week exercise program on oxidative stress and response to acute exercise among sedentary subjects |
| url | http://journalarticle.ukm.my/1092/ http://journalarticle.ukm.my/1092/ http://journalarticle.ukm.my/1092/1/jurnal72.pdf |