Tacrolimus pharmacogenetics: the influence of genetic polymorphisms of CYP3A5, MDRl and Pregnane X Receptor (PXR) in transplant patients / Professor Dr. Mohd Zaki Salleh and Associate Prof. Dr Teh Lay Kek
Tacrolimus is an immunosuppressant commonly used for long term in transplant patients to prevent organ rejection. Its use faces clinical challenges in achieving optimum dose for all patients. There are wide variation in doses of tacrolimus required for patients resulting in different drug levels and...
| Main Authors: | Salleh, Mohd Zaki, Teh, Lay Kek |
|---|---|
| Format: | Research Reports |
| Language: | English |
| Published: |
Research Management Institute (RMI)
2010
|
| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/9751/ |
Similar Items
Genetic polymorphism of drug metabolizing enzymes and estrogen receptor in pharmacogenetics of tamoxifen: implication for optimization of breast cancer treatment / Teh Lay Kek and Mohd Zaki Salleh
by: Lay Kek, Teh, et al.
Published: (2010)
by: Lay Kek, Teh, et al.
Published: (2010)
Cancer pharmacogenomics: the relevance of genetic profile in optimization drug therapy for azathiopurine and 5-fluorouracil / Prof Madya Dr Teh Lay Kek and Prof Dr Mohd Zaki Salleh
by: Teh, Lay Kek, et al.
Published: (2010)
by: Teh, Lay Kek, et al.
Published: (2010)
Transgenerational epigenetics in substance abuse: exploring the inheritable DNA methylation underlying the agressive behaviour and altered stress response. / Professor Dr Teh Lay Kek, Professor Dr Mohd Zaki Salleh and Dr. Richard Muhammad Johari James
by: Lay Kek, Teh, et al.
Published: (2016)
by: Lay Kek, Teh, et al.
Published: (2016)
Genetic polymorphism of CYP2C9 in patients on warfarin therapy and the clinical relevance / Teh Lay Kek... [et al.]
by: Teh, Lay Kek, et al.
Published: (2007)
by: Teh, Lay Kek, et al.
Published: (2007)
Cancerpharmacogenomics: the relevance of genetic
profile in optimization drug therapy for azathiopurine and
5-Fluorouracil / Teh Lay Kek And Mohd Zaki Salleh
by: Teh, Lay Kek, et al.
Published: (2010)
by: Teh, Lay Kek, et al.
Published: (2010)
Unraveling of the genetic polymorphism for ultra-rapid metabolism of phenytoin / Fazleen Haslinda Mohd Hatta , Prof Madya Dr The Lay Kek , Prof Dr Mohd Zaki Salleh
by: Mohd Hatta, Fazleen Haslinda, et al.
Published: (2010)
by: Mohd Hatta, Fazleen Haslinda, et al.
Published: (2010)
The role of pharmacogenetic variation in metoprolol CYP2D6 genotypes polymorphism
by: Wan Sulaiman, Wan Mohd. Azizi, et al.
Published: (2011)
by: Wan Sulaiman, Wan Mohd. Azizi, et al.
Published: (2011)
Design and Development of a Tractor Mounted Sweet Potato Transplanting Machine
by: Mohamed El Hassan, Mansour Widaa
Published: (2001)
by: Mohamed El Hassan, Mansour Widaa
Published: (2001)
Variability in responses of tacrolimus in kidney transplant patients: the use of pharmacogenetics and metabolomics in closing the gaps in clinical practices / Sharina Hamzah
by: Hamzah, Sharina
Published: (2013)
by: Hamzah, Sharina
Published: (2013)
Pharmacogenotyping of CYP3A5 in predicting dose-adjusted trough levels of tacrolimus among Malaysian kidney-transplant patients
by: Hamzah, Sharina, et al.
Published: (2014)
by: Hamzah, Sharina, et al.
Published: (2014)
Ovulation responses on three oestrus synchronisation protocol and association between progesterone concentration in late pregnancy and litter size of boer goats
by: Hassan Basri, Abdul Mu'in
Published: (2016)
by: Hassan Basri, Abdul Mu'in
Published: (2016)
Influence of polycyclic aromatic hydrocarbon and genetic polymorphisms (cyp1a1, gstm1, gstt1) on pyrene metabolite and dna damage among children in the Klang Valley, Malaysia
by: Hisamuddin, Nur Hazirah
Published: (2022)
by: Hisamuddin, Nur Hazirah
Published: (2022)
Investigating the functional properties of the multi-allelic copy number variable DEFA1A3 locus and their effects on gene expression and disease
by: AlHamidi, Reem
Published: (2023)
by: AlHamidi, Reem
Published: (2023)
Polymorphism of Haemoglobin-e in Selected Malaysian and the Maldives Populations
by: Saleem, Mohamed
Published: (2011)
by: Saleem, Mohamed
Published: (2011)
Analysis of genetic polymorphisms of TBX5, NKX2-5 and GATA4 cardiac transcription factor genes in Malaysian non syndromic congenital heart disease subjects
by: Khadhim, Nora F.
Published: (2012)
by: Khadhim, Nora F.
Published: (2012)
Influence of ORM1, PXR, CAR, CYP3A4 and CYP3A5 gene polymorphisms in mediating susceptibility risk to chronic myeloid leukaemia and response to imatinib mesylate therapy
by: Maddin, Najlaa
Published: (2017)
by: Maddin, Najlaa
Published: (2017)
The influence of genetic polymorphisms of CYP3A on the pharmacokinetic variation and clinical outcomes of tacrolimus in a cohort of patients / Mohd Rahimi Muda
by: Muda, Mohd Rahimi
Published: (2014)
by: Muda, Mohd Rahimi
Published: (2014)
A systematic review of the adverse effects of tacrolimus in organ transplant patients .
by: Teh, Lay Kek, et al.
Published: (2011)
by: Teh, Lay Kek, et al.
Published: (2011)
Pregnanes as molecular indicators for depositional environments of sediments and petroleum source rocks
by: Wang, Guangli, et al.
Published: (2015)
by: Wang, Guangli, et al.
Published: (2015)
The detection of polymorphism of RecKoRV Loci within the Victorian koala population
by: Dudeja, Sukanya
Published: (2023)
by: Dudeja, Sukanya
Published: (2023)
Cadmium concentration and genetic polymorphism of GSTM1, GSTP1 and GSTT1 in blood samples of respondents from Melaka, Malaysia
by: Md Zulkifli, Hamizah
Published: (2018)
by: Md Zulkifli, Hamizah
Published: (2018)
Genetic polymorphisms of endothelial marker, connexin and acyl-CoA genes among ethnic Malay subjects with essential hypertension
by: Salim, Elnaz
Published: (2020)
by: Salim, Elnaz
Published: (2020)
Influence of benzene and genetic polymorphisms towards internal metabolite changes and chromosomal damage among traffic policemen in the Klang Valley, Malaysia (RESTRICTED)
by: Noor Fatihah, Mohamad Fandi
Published: (2020)
by: Noor Fatihah, Mohamad Fandi
Published: (2020)
The acute impact of a hematopoietic allograft on lung function and inflammation: a prospective observational study
by: Enocson, Alexandra, et al.
Published: (2013)
by: Enocson, Alexandra, et al.
Published: (2013)
Modification, Performance and Adaptation of Manually Operated Transplanting and Seeding Machines for Lowland Paddy
by: Islam, Md. Syedul
Published: (1998)
by: Islam, Md. Syedul
Published: (1998)
Characterisation of erythropoietin gene-modified human mesenchymal stem cells and anti-apoptotic effect of glutamate excitotoxicity in a retinal neuron cell line
by: Shirley, Ding Suet Lee
Published: (2017)
by: Shirley, Ding Suet Lee
Published: (2017)
Vulnerability assessment and blue carbon potential of two mangrove sites in Malaysia / Teh Lay Hoon
by: Teh, Lay Hoon
Published: (2015)
by: Teh, Lay Hoon
Published: (2015)
Kek pop Masitah
by: Ishak, Mahani
Published: (2014)
by: Ishak, Mahani
Published: (2014)
Pipeline pharmacogenetics: A novel approach to integrating pharmacogenetics into drug development
by: Akkari, Patrick, et al.
Published: (2009)
by: Akkari, Patrick, et al.
Published: (2009)
Kidney transplant: graft and recipient profiling
by: O'Dair, Jonathan David
Published: (2009)
by: O'Dair, Jonathan David
Published: (2009)
A randomised controlled trial of a rehabilitation programme to assist physical and psychosocial recovery after stem cell transplantation
by: Bird, Lydia
Published: (2008)
by: Bird, Lydia
Published: (2008)
Xenotransplantation of caprine pancreatic islets in diabetic mice
by: Hani, Homayoun
Published: (2013)
by: Hani, Homayoun
Published: (2013)
Sequencing the OAS1 gene to map variation
by: Nalvelnathan, Janarth
Published: (2023)
by: Nalvelnathan, Janarth
Published: (2023)
Genetic relatedness among isolates of Acanthamoeba based on RAPD analysis
by: Abdul Manaf, Siti Ruhaya, et al.
Published: (2006)
by: Abdul Manaf, Siti Ruhaya, et al.
Published: (2006)
Single nucleotide polymorphism (SNP45) and plasma adiponectin level among antenatal women in selected polyclinics in Selangor
by: Low, Chen Fei
Published: (2009)
by: Low, Chen Fei
Published: (2009)
Interleukin-21 gene polymorphisms in Iranian multiple sclerosis subjects
by: Ahmadloo, Salma
Published: (2012)
by: Ahmadloo, Salma
Published: (2012)
Associations between immunologically - related genetic polymorphisms and cytokines expression on human leptospirosis susceptibility and severity
by: Wan Yusoff, Wan Shahriman Yushdie
Published: (2021)
by: Wan Yusoff, Wan Shahriman Yushdie
Published: (2021)
Association of GSTM1 and GSTT1 genetic polymorphism with blood methylmercury level and birth outcome among fish-eating urban pregnant women
by: Abedinlah, Amirah
Published: (2020)
by: Abedinlah, Amirah
Published: (2020)
Pulsed laser deposition of aluminium-doped zinc oxide films for optoelectronics application / Reeson Kek
by: Reeson , Kek
Published: (2017)
by: Reeson , Kek
Published: (2017)
Dikejutkan 'kek hari jadi'
Published: (2010)
Published: (2010)
Similar Items
-
Genetic polymorphism of drug metabolizing enzymes and estrogen receptor in pharmacogenetics of tamoxifen: implication for optimization of breast cancer treatment / Teh Lay Kek and Mohd Zaki Salleh
by: Lay Kek, Teh, et al.
Published: (2010) -
Cancer pharmacogenomics: the relevance of genetic profile in optimization drug therapy for azathiopurine and 5-fluorouracil / Prof Madya Dr Teh Lay Kek and Prof Dr Mohd Zaki Salleh
by: Teh, Lay Kek, et al.
Published: (2010) -
Transgenerational epigenetics in substance abuse: exploring the inheritable DNA methylation underlying the agressive behaviour and altered stress response. / Professor Dr Teh Lay Kek, Professor Dr Mohd Zaki Salleh and Dr. Richard Muhammad Johari James
by: Lay Kek, Teh, et al.
Published: (2016) -
Genetic polymorphism of CYP2C9 in patients on warfarin therapy and the clinical relevance / Teh Lay Kek... [et al.]
by: Teh, Lay Kek, et al.
Published: (2007) -
Cancerpharmacogenomics: the relevance of genetic
profile in optimization drug therapy for azathiopurine and
5-Fluorouracil / Teh Lay Kek And Mohd Zaki Salleh
by: Teh, Lay Kek, et al.
Published: (2010)