Antioxidant and antibacterial activities of leaves of murraya koenigii / Siti Noor Aziela Johari

Murraya koenigii is well known as curry leaf come from the family of Rutaceae. Presence of alkaloid and flavonoid from this plant are effective source of antioxidant and antimicrobial on development of newer therapeutics treatment. In this study, three different solvent with different polarity which...

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Main Author: Johari, Siti Noor Aziela
Format: Student Project
Language:English
Published: 2017
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/35093/
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author Johari, Siti Noor Aziela
author_facet Johari, Siti Noor Aziela
author_sort Johari, Siti Noor Aziela
building UiTM Institutional Repository
collection Online Access
description Murraya koenigii is well known as curry leaf come from the family of Rutaceae. Presence of alkaloid and flavonoid from this plant are effective source of antioxidant and antimicrobial on development of newer therapeutics treatment. In this study, three different solvent with different polarity which is petroleum ether, dichloromethane and methanol had been used to extract M. koenigii leaves using soxhlet extractor. Methanol extraction had shown the highest percentage yield with 8.1 % compared to dichloromethane and petroleum ether with 5.2 % and 4.7 % respectively. The extracts also used to measure their antioxidant and antimicrobial activity by using DPPH scavenging assay and Disc diffusion methods. The highest percentage of inhibition in antioxidant at 1000 μg/ml was showed by methanol extract with 85.3 % when compared with standard ascorbic acid followed by dichloromethane, 82.5% and petroleum ether, 84.9 %. Besides, IC50 value of methanol extract was 110.0 μg/ml in antioxidant activity of M. koenigii. Dichloromethane and petroleum ether extracts showed strong antibacterial activity against S. thypi with 20.0 and 23.0 mm inhibition zone respectively.
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institution Universiti Teknologi MARA
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publishDate 2017
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spelling uitm-350932020-10-15T14:58:42Z https://ir.uitm.edu.my/id/eprint/35093/ Antioxidant and antibacterial activities of leaves of murraya koenigii / Siti Noor Aziela Johari Johari, Siti Noor Aziela Laboratories. General works Extraction (Chemistry) Antibacterial agents Murraya koenigii is well known as curry leaf come from the family of Rutaceae. Presence of alkaloid and flavonoid from this plant are effective source of antioxidant and antimicrobial on development of newer therapeutics treatment. In this study, three different solvent with different polarity which is petroleum ether, dichloromethane and methanol had been used to extract M. koenigii leaves using soxhlet extractor. Methanol extraction had shown the highest percentage yield with 8.1 % compared to dichloromethane and petroleum ether with 5.2 % and 4.7 % respectively. The extracts also used to measure their antioxidant and antimicrobial activity by using DPPH scavenging assay and Disc diffusion methods. The highest percentage of inhibition in antioxidant at 1000 μg/ml was showed by methanol extract with 85.3 % when compared with standard ascorbic acid followed by dichloromethane, 82.5% and petroleum ether, 84.9 %. Besides, IC50 value of methanol extract was 110.0 μg/ml in antioxidant activity of M. koenigii. Dichloromethane and petroleum ether extracts showed strong antibacterial activity against S. thypi with 20.0 and 23.0 mm inhibition zone respectively. 2017 Student Project NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/35093/1/35093.pdf Johari, Siti Noor Aziela (2017) Antioxidant and antibacterial activities of leaves of murraya koenigii / Siti Noor Aziela Johari. (2017) [Student Project] (Unpublished)
spellingShingle Laboratories. General works
Extraction (Chemistry)
Antibacterial agents
Johari, Siti Noor Aziela
Antioxidant and antibacterial activities of leaves of murraya koenigii / Siti Noor Aziela Johari
title Antioxidant and antibacterial activities of leaves of murraya koenigii / Siti Noor Aziela Johari
title_full Antioxidant and antibacterial activities of leaves of murraya koenigii / Siti Noor Aziela Johari
title_fullStr Antioxidant and antibacterial activities of leaves of murraya koenigii / Siti Noor Aziela Johari
title_full_unstemmed Antioxidant and antibacterial activities of leaves of murraya koenigii / Siti Noor Aziela Johari
title_short Antioxidant and antibacterial activities of leaves of murraya koenigii / Siti Noor Aziela Johari
title_sort antioxidant and antibacterial activities of leaves of murraya koenigii / siti noor aziela johari
topic Laboratories. General works
Extraction (Chemistry)
Antibacterial agents
url https://ir.uitm.edu.my/id/eprint/35093/