Synthesis, spectral characterisation and antimicrobial properties of Cu(II) and Fe(II) complexes with xanthone / Rabuyah Ni, Mohammad Isa Mohamadin and Vivien Yi Mian Jong
The new complexes [CuL2(H2O)2] and [FeL2(CH3O)2] in which L = β-mangostin were synthesised and characterised. The structure of the ligand, β-mangostin was confirmed using NMR and the purity of ligand was determined using HPLC. Both Cu(II) and Fe(II) complexes were prepared by reaction between the li...
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| Format: | Article |
| Language: | English |
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Universiti Teknologi MARA Shah Alam
2017
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| Online Access: | https://ir.uitm.edu.my/id/eprint/34779/ |
| _version_ | 1848808629327626240 |
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| author | Ni, Rabuyah Mohamadin, Mohammad Isa Mian Jong, Vivien Yi |
| author_facet | Ni, Rabuyah Mohamadin, Mohammad Isa Mian Jong, Vivien Yi |
| author_sort | Ni, Rabuyah |
| building | UiTM Institutional Repository |
| collection | Online Access |
| description | The new complexes [CuL2(H2O)2] and [FeL2(CH3O)2] in which L = β-mangostin were synthesised and characterised. The structure of the ligand, β-mangostin was confirmed using NMR and the purity of ligand was determined using HPLC. Both Cu(II) and Fe(II) complexes were prepared by reaction between the ligand and the acetate of the metals in one-step reaction. The synthesised compounds have been characterised using UV-Visible, FTIR and CHNS analyser. Ligand and metal complexes were tested against bacteria to assess on their antimicrobial properties using Minimum Inhibitory Concentrations (MICs) and Minimum Bactericidal Concentrations (MBCs) method. The elemental analysis and spectra data suggested octahedral geometry for both Cu(II) and Fe(II) complexes. The IR spectroscopy revealed that the chelation of Cu2+ and Fe2+ ion occurred with hydroxyl and carbonyl group at C9 and C1 respectively of β-mangostin. Both Cu(II) and Fe(II) complexes showed stronger inhibition against Pseudomonas aeruginosa, Proteus vulgaris, Klebsiella pneumoniae and Salmonella pneumonia at concentration 900 mg/mL and Escherichia coli at 450 mg/mL compared to the ligand itself. |
| first_indexed | 2025-11-14T23:01:45Z |
| format | Article |
| id | uitm-34779 |
| institution | Universiti Teknologi MARA |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T23:01:45Z |
| publishDate | 2017 |
| publisher | Universiti Teknologi MARA Shah Alam |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uitm-347792020-09-29T06:54:28Z https://ir.uitm.edu.my/id/eprint/34779/ Synthesis, spectral characterisation and antimicrobial properties of Cu(II) and Fe(II) complexes with xanthone / Rabuyah Ni, Mohammad Isa Mohamadin and Vivien Yi Mian Jong srj Ni, Rabuyah Mohamadin, Mohammad Isa Mian Jong, Vivien Yi Microbial ecology The new complexes [CuL2(H2O)2] and [FeL2(CH3O)2] in which L = β-mangostin were synthesised and characterised. The structure of the ligand, β-mangostin was confirmed using NMR and the purity of ligand was determined using HPLC. Both Cu(II) and Fe(II) complexes were prepared by reaction between the ligand and the acetate of the metals in one-step reaction. The synthesised compounds have been characterised using UV-Visible, FTIR and CHNS analyser. Ligand and metal complexes were tested against bacteria to assess on their antimicrobial properties using Minimum Inhibitory Concentrations (MICs) and Minimum Bactericidal Concentrations (MBCs) method. The elemental analysis and spectra data suggested octahedral geometry for both Cu(II) and Fe(II) complexes. The IR spectroscopy revealed that the chelation of Cu2+ and Fe2+ ion occurred with hydroxyl and carbonyl group at C9 and C1 respectively of β-mangostin. Both Cu(II) and Fe(II) complexes showed stronger inhibition against Pseudomonas aeruginosa, Proteus vulgaris, Klebsiella pneumoniae and Salmonella pneumonia at concentration 900 mg/mL and Escherichia coli at 450 mg/mL compared to the ligand itself. Universiti Teknologi MARA Shah Alam 2017-01 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/34779/1/34779.pdf Ni, Rabuyah and Mohamadin, Mohammad Isa and Mian Jong, Vivien Yi (2017) Synthesis, spectral characterisation and antimicrobial properties of Cu(II) and Fe(II) complexes with xanthone / Rabuyah Ni, Mohammad Isa Mohamadin and Vivien Yi Mian Jong. (2017) Scientific Research Journal <https://ir.uitm.edu.my/view/publication/Scientific_Research_Journal.html>, 14 (1). pp. 1-14. ISSN 2289-649X https://srj.uitm.edu.my/ https://doi.org/10.24191/srj.v14i1.9368 https://doi.org/10.24191/srj.v14i1.9368 |
| spellingShingle | Microbial ecology Ni, Rabuyah Mohamadin, Mohammad Isa Mian Jong, Vivien Yi Synthesis, spectral characterisation and antimicrobial properties of Cu(II) and Fe(II) complexes with xanthone / Rabuyah Ni, Mohammad Isa Mohamadin and Vivien Yi Mian Jong |
| title | Synthesis, spectral characterisation and antimicrobial properties of Cu(II) and Fe(II) complexes with xanthone / Rabuyah Ni, Mohammad Isa Mohamadin and Vivien Yi Mian Jong |
| title_full | Synthesis, spectral characterisation and antimicrobial properties of Cu(II) and Fe(II) complexes with xanthone / Rabuyah Ni, Mohammad Isa Mohamadin and Vivien Yi Mian Jong |
| title_fullStr | Synthesis, spectral characterisation and antimicrobial properties of Cu(II) and Fe(II) complexes with xanthone / Rabuyah Ni, Mohammad Isa Mohamadin and Vivien Yi Mian Jong |
| title_full_unstemmed | Synthesis, spectral characterisation and antimicrobial properties of Cu(II) and Fe(II) complexes with xanthone / Rabuyah Ni, Mohammad Isa Mohamadin and Vivien Yi Mian Jong |
| title_short | Synthesis, spectral characterisation and antimicrobial properties of Cu(II) and Fe(II) complexes with xanthone / Rabuyah Ni, Mohammad Isa Mohamadin and Vivien Yi Mian Jong |
| title_sort | synthesis, spectral characterisation and antimicrobial properties of cu(ii) and fe(ii) complexes with xanthone / rabuyah ni, mohammad isa mohamadin and vivien yi mian jong |
| topic | Microbial ecology |
| url | https://ir.uitm.edu.my/id/eprint/34779/ https://ir.uitm.edu.my/id/eprint/34779/ https://ir.uitm.edu.my/id/eprint/34779/ |