Methanolic extract of muntingia calabura leaves & aloe vera gel against selected pathogenic bacteria / Nur Aisyah Izzati Azman

Muntingia calabura is the common roadside trees that had been neglected despite having medicinal values, while Aloe vera is the common plant used for antibacterial agent. Hence the purpose of this study is not only to identify and compare the effectiveness of antibacterial activity of both samples b...

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Main Author: Azman, Nur Aisyah Izzati
Format: Student Project
Language:English
Published: 2017
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/32170/
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author Azman, Nur Aisyah Izzati
author_facet Azman, Nur Aisyah Izzati
author_sort Azman, Nur Aisyah Izzati
building UiTM Institutional Repository
collection Online Access
description Muntingia calabura is the common roadside trees that had been neglected despite having medicinal values, while Aloe vera is the common plant used for antibacterial agent. Hence the purpose of this study is not only to identify and compare the effectiveness of antibacterial activity of both samples but also to provide ground prove of the advantages that can be taken from Muntingia calabura in terms of its antibacterial activity as alternative. From the study, there are significant difference of antibacterial activity between M. calabura and Aloe vera against the E. coli, S.typhi, S.aureus and B. subtilis as statistically analysis shows that p<0.05. The difference indiameters of zone of inhibition obtained through the study was also significant. It wasfound that methanolic extract of M. calabura showed greater inhibitions at 100mg/mL and 50 mg/mL as compared to the synthetic drug, streptomycin. From Table4.1, the highest mean value obtained at 100 mg/mL for E. coli, S. typhi, S. aureus andB.subtilis respectively was 3.33±5.77 mm, 12.00±1.00 mm, 9.00±7.81 mm, and16.67±6.03 mm whereas Aloe vera showed none. To conclude, M. calabura extractshowed promising potential as antibacterial agent compared to commonly used Aloevera for future drug development. It was also found that the extract was dose-dependent hence the studies can be done by using several higher dose concentrationsand adding the biochemistry test to the plant extract.
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format Student Project
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institution Universiti Teknologi MARA
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publishDate 2017
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spelling uitm-321702022-12-01T03:11:55Z https://ir.uitm.edu.my/id/eprint/32170/ Methanolic extract of muntingia calabura leaves & aloe vera gel against selected pathogenic bacteria / Nur Aisyah Izzati Azman Azman, Nur Aisyah Izzati Extraction (Chemistry) Bacteria Muntingia calabura is the common roadside trees that had been neglected despite having medicinal values, while Aloe vera is the common plant used for antibacterial agent. Hence the purpose of this study is not only to identify and compare the effectiveness of antibacterial activity of both samples but also to provide ground prove of the advantages that can be taken from Muntingia calabura in terms of its antibacterial activity as alternative. From the study, there are significant difference of antibacterial activity between M. calabura and Aloe vera against the E. coli, S.typhi, S.aureus and B. subtilis as statistically analysis shows that p<0.05. The difference indiameters of zone of inhibition obtained through the study was also significant. It wasfound that methanolic extract of M. calabura showed greater inhibitions at 100mg/mL and 50 mg/mL as compared to the synthetic drug, streptomycin. From Table4.1, the highest mean value obtained at 100 mg/mL for E. coli, S. typhi, S. aureus andB.subtilis respectively was 3.33±5.77 mm, 12.00±1.00 mm, 9.00±7.81 mm, and16.67±6.03 mm whereas Aloe vera showed none. To conclude, M. calabura extractshowed promising potential as antibacterial agent compared to commonly used Aloevera for future drug development. It was also found that the extract was dose-dependent hence the studies can be done by using several higher dose concentrationsand adding the biochemistry test to the plant extract. 2017 Student Project NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/32170/2/32170.pdf Azman, Nur Aisyah Izzati (2017) Methanolic extract of muntingia calabura leaves & aloe vera gel against selected pathogenic bacteria / Nur Aisyah Izzati Azman. (2017) [Student Project] <http://terminalib.uitm.edu.my/32170.pdf> (Unpublished)
spellingShingle Extraction (Chemistry)
Bacteria
Azman, Nur Aisyah Izzati
Methanolic extract of muntingia calabura leaves & aloe vera gel against selected pathogenic bacteria / Nur Aisyah Izzati Azman
title Methanolic extract of muntingia calabura leaves & aloe vera gel against selected pathogenic bacteria / Nur Aisyah Izzati Azman
title_full Methanolic extract of muntingia calabura leaves & aloe vera gel against selected pathogenic bacteria / Nur Aisyah Izzati Azman
title_fullStr Methanolic extract of muntingia calabura leaves & aloe vera gel against selected pathogenic bacteria / Nur Aisyah Izzati Azman
title_full_unstemmed Methanolic extract of muntingia calabura leaves & aloe vera gel against selected pathogenic bacteria / Nur Aisyah Izzati Azman
title_short Methanolic extract of muntingia calabura leaves & aloe vera gel against selected pathogenic bacteria / Nur Aisyah Izzati Azman
title_sort methanolic extract of muntingia calabura leaves & aloe vera gel against selected pathogenic bacteria / nur aisyah izzati azman
topic Extraction (Chemistry)
Bacteria
url https://ir.uitm.edu.my/id/eprint/32170/