Evaluation of ampicillin, vancomycin, and gentamycin antibiotic resistant among lactobacillus isolates / Rozila Alias... [et al.]
Antibiotic resistance is an ever-increasing in worldwide problem nowadays. It is happened when the exten- sive use of antibiotics which will creates the selective pressure resulting from mutation of normal genes and spreading of a variety of an antimicrobial resistance. Uses of Lactobacillus as pr...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universiti Teknologi MARA, Negeri Sembilan
2019
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| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/30677/ |
| _version_ | 1848807559186612224 |
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| author | Alias, Rozila Thivyah, Karunageran Mustakim, Maimunah Kamal, Siti Nurfatehah Mohtar, Siti Hasmah Hassan, Siti Rahayu Salina, Murni Ahmad Khairuddin, Siti Amalina Muhammad Ali, Hasliza Mohammad Nawawi, Norazah Lani, Mohd Nizam Ibrahim, Abdul Latif |
| author_facet | Alias, Rozila Thivyah, Karunageran Mustakim, Maimunah Kamal, Siti Nurfatehah Mohtar, Siti Hasmah Hassan, Siti Rahayu Salina, Murni Ahmad Khairuddin, Siti Amalina Muhammad Ali, Hasliza Mohammad Nawawi, Norazah Lani, Mohd Nizam Ibrahim, Abdul Latif |
| author_sort | Alias, Rozila |
| building | UiTM Institutional Repository |
| collection | Online Access |
| description | Antibiotic resistance is an ever-increasing in worldwide problem nowadays. It is happened when the exten-
sive use of antibiotics which will creates the selective pressure resulting from mutation of normal genes and
spreading of a variety of an antimicrobial resistance. Uses of Lactobacillus as probiotics or in starter cultures may serve as hosts of antibiotic resistance genes, which could be transfer or resistance to multiple antibiotics. Therefore, it is important to screen the susceptible or resistance towards antibiotics which will not transferable resistance genes. In the recent study, a total of 37 strains of Lactobacillus species isolated from various milk and dairy products such as goat’s milk, cattle’s milk, human’s milk, homemade yogurt and
commercial yogurt were examined for the antibiotic profile using Kirby-Bauer method. The results of this study show that human’s milk has a high number of Lactobacillus isolates resistant to ampicillin (75%), vancomycin (62.5%) and gentamycin (62.5%). Whereas Lactobacillus isolated from cattle’s milk have resistant to ampicillin (42.1%), vancomycin (42.1%) and susceptible to gentamycin (0%). But however, goat’s milk still has lower percentage number of resistant to ampicillin (28.0%), vancomycin (14.3%) and
are susceptible to gentamycin (0%). These results indicate that ampicillin and vancomycin resistant seems
to be very common among Lactobacillus isolates but gentamycin are still susceptible used. Vancomycin
resistant are more concerned because of the emerging problem in hospital and often described as one of the
last resorts against the infection caused by multidrug-resistant pathogens. Therefore, lactobacilli as probiot-
ics would be more monitoring when applied in food industry and clinical especially for immune compromised patients or during anti-biotherapy. Acquisition and retransfer of resistance genes should be addressed in the new safety aspects of probiotics uses.addressed in the new safety aspects of probiotics uses. |
| first_indexed | 2025-11-14T22:44:45Z |
| format | Article |
| id | uitm-30677 |
| institution | Universiti Teknologi MARA |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T22:44:45Z |
| publishDate | 2019 |
| publisher | Universiti Teknologi MARA, Negeri Sembilan |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uitm-306772020-06-01T02:02:30Z https://ir.uitm.edu.my/id/eprint/30677/ Evaluation of ampicillin, vancomycin, and gentamycin antibiotic resistant among lactobacillus isolates / Rozila Alias... [et al.] joa Alias, Rozila Thivyah, Karunageran Mustakim, Maimunah Kamal, Siti Nurfatehah Mohtar, Siti Hasmah Hassan, Siti Rahayu Salina, Murni Ahmad Khairuddin, Siti Amalina Muhammad Ali, Hasliza Mohammad Nawawi, Norazah Lani, Mohd Nizam Ibrahim, Abdul Latif Physical and theoretical chemistry Antibiotic resistance is an ever-increasing in worldwide problem nowadays. It is happened when the exten- sive use of antibiotics which will creates the selective pressure resulting from mutation of normal genes and spreading of a variety of an antimicrobial resistance. Uses of Lactobacillus as probiotics or in starter cultures may serve as hosts of antibiotic resistance genes, which could be transfer or resistance to multiple antibiotics. Therefore, it is important to screen the susceptible or resistance towards antibiotics which will not transferable resistance genes. In the recent study, a total of 37 strains of Lactobacillus species isolated from various milk and dairy products such as goat’s milk, cattle’s milk, human’s milk, homemade yogurt and commercial yogurt were examined for the antibiotic profile using Kirby-Bauer method. The results of this study show that human’s milk has a high number of Lactobacillus isolates resistant to ampicillin (75%), vancomycin (62.5%) and gentamycin (62.5%). Whereas Lactobacillus isolated from cattle’s milk have resistant to ampicillin (42.1%), vancomycin (42.1%) and susceptible to gentamycin (0%). But however, goat’s milk still has lower percentage number of resistant to ampicillin (28.0%), vancomycin (14.3%) and are susceptible to gentamycin (0%). These results indicate that ampicillin and vancomycin resistant seems to be very common among Lactobacillus isolates but gentamycin are still susceptible used. Vancomycin resistant are more concerned because of the emerging problem in hospital and often described as one of the last resorts against the infection caused by multidrug-resistant pathogens. Therefore, lactobacilli as probiot- ics would be more monitoring when applied in food industry and clinical especially for immune compromised patients or during anti-biotherapy. Acquisition and retransfer of resistance genes should be addressed in the new safety aspects of probiotics uses.addressed in the new safety aspects of probiotics uses. Universiti Teknologi MARA, Negeri Sembilan 2019 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/30677/1/30677.pdf Alias, Rozila and Thivyah, Karunageran and Mustakim, Maimunah and Kamal, Siti Nurfatehah and Mohtar, Siti Hasmah and Hassan, Siti Rahayu and Salina, Murni and Ahmad Khairuddin, Siti Amalina and Muhammad Ali, Hasliza and Mohammad Nawawi, Norazah and Lani, Mohd Nizam and Ibrahim, Abdul Latif (2019) Evaluation of ampicillin, vancomycin, and gentamycin antibiotic resistant among lactobacillus isolates / Rozila Alias... [et al.]. (2019) Journal of Academia <https://ir.uitm.edu.my/view/publication/Journal_of_Academia.html>, 7 (2). pp. 104-111. ISSN 2289-6368 https://nsembilan.uitm.edu.my/joacns/ |
| spellingShingle | Physical and theoretical chemistry Alias, Rozila Thivyah, Karunageran Mustakim, Maimunah Kamal, Siti Nurfatehah Mohtar, Siti Hasmah Hassan, Siti Rahayu Salina, Murni Ahmad Khairuddin, Siti Amalina Muhammad Ali, Hasliza Mohammad Nawawi, Norazah Lani, Mohd Nizam Ibrahim, Abdul Latif Evaluation of ampicillin, vancomycin, and gentamycin antibiotic resistant among lactobacillus isolates / Rozila Alias... [et al.] |
| title | Evaluation of ampicillin, vancomycin, and gentamycin antibiotic resistant among lactobacillus isolates / Rozila Alias... [et al.] |
| title_full | Evaluation of ampicillin, vancomycin, and gentamycin antibiotic resistant among lactobacillus isolates / Rozila Alias... [et al.] |
| title_fullStr | Evaluation of ampicillin, vancomycin, and gentamycin antibiotic resistant among lactobacillus isolates / Rozila Alias... [et al.] |
| title_full_unstemmed | Evaluation of ampicillin, vancomycin, and gentamycin antibiotic resistant among lactobacillus isolates / Rozila Alias... [et al.] |
| title_short | Evaluation of ampicillin, vancomycin, and gentamycin antibiotic resistant among lactobacillus isolates / Rozila Alias... [et al.] |
| title_sort | evaluation of ampicillin, vancomycin, and gentamycin antibiotic resistant among lactobacillus isolates / rozila alias... [et al.] |
| topic | Physical and theoretical chemistry |
| url | https://ir.uitm.edu.my/id/eprint/30677/ https://ir.uitm.edu.my/id/eprint/30677/ |