The preliminary cytotoxicity study: anti-proliferative activity of aqueous extract of clinacanthus nutans, strobilanther crispa and pereskia bleo on oral squamous carcinoma cells orl-48 / Rahayu Zulkapli and Fathilah Abdul Razak.
This in vitro study was carried out to screen the aqueous extracts of selected local plants (clinacanthus nutans, strobilanther crispa and pereskia bleo) known locally to possess anticancer properties for cytotoxic activity. Method: The antiproliferative activity on human oral squamous cell carcinom...
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| Format: | Conference or Workshop Item |
| Language: | English |
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2019
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| Online Access: | https://ir.uitm.edu.my/id/eprint/30159/ |
| _version_ | 1848807424677380096 |
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| author | Zulkapli, Rahayu Abdul Razak, Fathilah |
| author_facet | Zulkapli, Rahayu Abdul Razak, Fathilah |
| author_sort | Zulkapli, Rahayu |
| building | UiTM Institutional Repository |
| collection | Online Access |
| description | This in vitro study was carried out to screen the aqueous extracts of selected local plants (clinacanthus nutans, strobilanther crispa and pereskia bleo) known locally to possess anticancer properties for cytotoxic activity. Method: The antiproliferative activity on human oral squamous cell carcinoma, ORL-48 was assessed based on a colorimetric assay using neutral red dye. Result: Clinacanthus nutans exhibited an IC50 of 49.8 ± 0.02 µg/mL on ORL-48 cells, while Strobilanther crispa and Pereskia bleo showed no antiproliferative response. Conclusion: The aqueous extract of clinacanthus nutans, strobilanther crispa and pereskia bleo does not possess anti proliferative activity towards oral squamous carcinoma cells ORL-48. |
| first_indexed | 2025-11-14T22:42:36Z |
| format | Conference or Workshop Item |
| id | uitm-30159 |
| institution | Universiti Teknologi MARA |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T22:42:36Z |
| publishDate | 2019 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uitm-301592020-04-23T03:18:22Z https://ir.uitm.edu.my/id/eprint/30159/ The preliminary cytotoxicity study: anti-proliferative activity of aqueous extract of clinacanthus nutans, strobilanther crispa and pereskia bleo on oral squamous carcinoma cells orl-48 / Rahayu Zulkapli and Fathilah Abdul Razak. Zulkapli, Rahayu Abdul Razak, Fathilah Oral and dental medicine. Pathology. Diseases Prosthetic dentistry. Prosthodontics This in vitro study was carried out to screen the aqueous extracts of selected local plants (clinacanthus nutans, strobilanther crispa and pereskia bleo) known locally to possess anticancer properties for cytotoxic activity. Method: The antiproliferative activity on human oral squamous cell carcinoma, ORL-48 was assessed based on a colorimetric assay using neutral red dye. Result: Clinacanthus nutans exhibited an IC50 of 49.8 ± 0.02 µg/mL on ORL-48 cells, while Strobilanther crispa and Pereskia bleo showed no antiproliferative response. Conclusion: The aqueous extract of clinacanthus nutans, strobilanther crispa and pereskia bleo does not possess anti proliferative activity towards oral squamous carcinoma cells ORL-48. 2019 Conference or Workshop Item PeerReviewed text en https://ir.uitm.edu.my/id/eprint/30159/1/K_RAHAYU%20ZULKAPLI%20DSSS%20B%2019.pdf Zulkapli, Rahayu and Abdul Razak, Fathilah (2019) The preliminary cytotoxicity study: anti-proliferative activity of aqueous extract of clinacanthus nutans, strobilanther crispa and pereskia bleo on oral squamous carcinoma cells orl-48 / Rahayu Zulkapli and Fathilah Abdul Razak. (2019) In: Proceedings of 9th Dental Student’s Scientific Symposium,Malaysia (Malaysia, 2019), 9th – 10th April 2019, Faculty Dentistry, Universiti Teknologi MARA. https://dentistry.uitm.edu.my/v2/images/images/DSS/proceeding/vol1/pdf/08.pdf? |
| spellingShingle | Oral and dental medicine. Pathology. Diseases Prosthetic dentistry. Prosthodontics Zulkapli, Rahayu Abdul Razak, Fathilah The preliminary cytotoxicity study: anti-proliferative activity of aqueous extract of clinacanthus nutans, strobilanther crispa and pereskia bleo on oral squamous carcinoma cells orl-48 / Rahayu Zulkapli and Fathilah Abdul Razak. |
| title | The preliminary cytotoxicity study: anti-proliferative activity of aqueous extract of clinacanthus nutans, strobilanther crispa and pereskia bleo on oral squamous carcinoma cells orl-48 / Rahayu Zulkapli and Fathilah Abdul Razak. |
| title_full | The preliminary cytotoxicity study: anti-proliferative activity of aqueous extract of clinacanthus nutans, strobilanther crispa and pereskia bleo on oral squamous carcinoma cells orl-48 / Rahayu Zulkapli and Fathilah Abdul Razak. |
| title_fullStr | The preliminary cytotoxicity study: anti-proliferative activity of aqueous extract of clinacanthus nutans, strobilanther crispa and pereskia bleo on oral squamous carcinoma cells orl-48 / Rahayu Zulkapli and Fathilah Abdul Razak. |
| title_full_unstemmed | The preliminary cytotoxicity study: anti-proliferative activity of aqueous extract of clinacanthus nutans, strobilanther crispa and pereskia bleo on oral squamous carcinoma cells orl-48 / Rahayu Zulkapli and Fathilah Abdul Razak. |
| title_short | The preliminary cytotoxicity study: anti-proliferative activity of aqueous extract of clinacanthus nutans, strobilanther crispa and pereskia bleo on oral squamous carcinoma cells orl-48 / Rahayu Zulkapli and Fathilah Abdul Razak. |
| title_sort | preliminary cytotoxicity study: anti-proliferative activity of aqueous extract of clinacanthus nutans, strobilanther crispa and pereskia bleo on oral squamous carcinoma cells orl-48 / rahayu zulkapli and fathilah abdul razak. |
| topic | Oral and dental medicine. Pathology. Diseases Prosthetic dentistry. Prosthodontics |
| url | https://ir.uitm.edu.my/id/eprint/30159/ https://ir.uitm.edu.my/id/eprint/30159/ |