Development of folliculitis in a patient with recalcitrant pustular psoriasis following acitretin treatment: a case report / Nur Ashikin Ahmad, Tarita Taib and Meera Kuppusamy.
Oral retinoids are among the drugs of choice for pustular psoriasis. Therapy with retinoids, including acitretin, is potent teratogens with other common side effects such as mucocutaneous involvement. Mucocutaneous side effects including dry lips (cheilitis), skin peeling, hair loss (alopecia), dry...
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| Format: | Article |
| Language: | English |
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Universiti Teknologi MARA Cawangan Selangor
2017
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| Online Access: | https://ir.uitm.edu.my/id/eprint/30086/ |
| _version_ | 1848807407242706944 |
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| author | Ahmad, Nur Ashikin Taib, Tarita Kuppusamy, Meera |
| author_facet | Ahmad, Nur Ashikin Taib, Tarita Kuppusamy, Meera |
| author_sort | Ahmad, Nur Ashikin |
| building | UiTM Institutional Repository |
| collection | Online Access |
| description | Oral retinoids are among the drugs of choice for pustular psoriasis. Therapy with retinoids, including acitretin, is potent teratogens with other common side effects such as mucocutaneous involvement. Mucocutaneous side effects including dry lips (cheilitis), skin peeling, hair loss (alopecia), dry skin, or rhinitis are dose-related, with cheilitis occurring in more than 75% of patients receiving the highest doses of acitretin (75 mg/day). We report on a 37-year-old woman who developed folliculitis with acitretin which is a rare cutaneous side effect. She presented with eruptions pruritic papules with follicular pattern on anterior thigh and forearms after almost 1 year of treatment with acitretin (50mg OD) for pustular psoriasis. The skin lesion was treated successfully with skin dressing and antibiotic treatment and skin biopsy is suggestive of folliculitis. Several treatments for pustular psoriasis including topical steroids, methotrexate and oral prednisolone were ineffective or not tolerated. Treatment with acitretin which are 50mg OD provided partial resolution of skin lesions. The case is hereby reported because of its rarity and folliculitis must be considered in the differential diagnosis of a popular eruption, especially in patients with high dose acitretin. |
| first_indexed | 2025-11-14T22:42:20Z |
| format | Article |
| id | uitm-30086 |
| institution | Universiti Teknologi MARA |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T22:42:20Z |
| publishDate | 2017 |
| publisher | Universiti Teknologi MARA Cawangan Selangor |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uitm-300862020-04-22T05:18:51Z https://ir.uitm.edu.my/id/eprint/30086/ Development of folliculitis in a patient with recalcitrant pustular psoriasis following acitretin treatment: a case report / Nur Ashikin Ahmad, Tarita Taib and Meera Kuppusamy. jchs Ahmad, Nur Ashikin Taib, Tarita Kuppusamy, Meera RL Dermatology Skin manifestations of systemic disease Oral retinoids are among the drugs of choice for pustular psoriasis. Therapy with retinoids, including acitretin, is potent teratogens with other common side effects such as mucocutaneous involvement. Mucocutaneous side effects including dry lips (cheilitis), skin peeling, hair loss (alopecia), dry skin, or rhinitis are dose-related, with cheilitis occurring in more than 75% of patients receiving the highest doses of acitretin (75 mg/day). We report on a 37-year-old woman who developed folliculitis with acitretin which is a rare cutaneous side effect. She presented with eruptions pruritic papules with follicular pattern on anterior thigh and forearms after almost 1 year of treatment with acitretin (50mg OD) for pustular psoriasis. The skin lesion was treated successfully with skin dressing and antibiotic treatment and skin biopsy is suggestive of folliculitis. Several treatments for pustular psoriasis including topical steroids, methotrexate and oral prednisolone were ineffective or not tolerated. Treatment with acitretin which are 50mg OD provided partial resolution of skin lesions. The case is hereby reported because of its rarity and folliculitis must be considered in the differential diagnosis of a popular eruption, especially in patients with high dose acitretin. Universiti Teknologi MARA Cawangan Selangor 2017-06 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/30086/1/AJ_NUR%20ASHIKIN%20AHMAD%20JCHS%20B%2017.pdf Ahmad, Nur Ashikin and Taib, Tarita and Kuppusamy, Meera (2017) Development of folliculitis in a patient with recalcitrant pustular psoriasis following acitretin treatment: a case report / Nur Ashikin Ahmad, Tarita Taib and Meera Kuppusamy. (2017) Journal of Clinical and Health Sciences <https://ir.uitm.edu.my/view/publication/Journal_of_Clinical_and_Health_Sciences.html>, 2 (1). pp. 1-4. ISSN 0127-984X https://jchs-medicine.uitm.edu.my/index.php |
| spellingShingle | RL Dermatology Skin manifestations of systemic disease Ahmad, Nur Ashikin Taib, Tarita Kuppusamy, Meera Development of folliculitis in a patient with recalcitrant pustular psoriasis following acitretin treatment: a case report / Nur Ashikin Ahmad, Tarita Taib and Meera Kuppusamy. |
| title | Development of folliculitis in a patient with recalcitrant pustular psoriasis following acitretin treatment: a case report / Nur Ashikin Ahmad, Tarita Taib and Meera Kuppusamy. |
| title_full | Development of folliculitis in a patient with recalcitrant pustular psoriasis following acitretin treatment: a case report / Nur Ashikin Ahmad, Tarita Taib and Meera Kuppusamy. |
| title_fullStr | Development of folliculitis in a patient with recalcitrant pustular psoriasis following acitretin treatment: a case report / Nur Ashikin Ahmad, Tarita Taib and Meera Kuppusamy. |
| title_full_unstemmed | Development of folliculitis in a patient with recalcitrant pustular psoriasis following acitretin treatment: a case report / Nur Ashikin Ahmad, Tarita Taib and Meera Kuppusamy. |
| title_short | Development of folliculitis in a patient with recalcitrant pustular psoriasis following acitretin treatment: a case report / Nur Ashikin Ahmad, Tarita Taib and Meera Kuppusamy. |
| title_sort | development of folliculitis in a patient with recalcitrant pustular psoriasis following acitretin treatment: a case report / nur ashikin ahmad, tarita taib and meera kuppusamy. |
| topic | RL Dermatology Skin manifestations of systemic disease |
| url | https://ir.uitm.edu.my/id/eprint/30086/ https://ir.uitm.edu.my/id/eprint/30086/ |