Shrinking Lung Syndrome – A rare cause of recurrent dyspnoea in SLE / Hazlyna Baharuddin … [et al.]

Here we present a 24-year-old lady with systemic lupus erythematosus (SLE) whom we diagnosed with shrinking lung syndrome (SLS), a rare manifestation of SLE. The initial SLE manifestation was alopecia, thrombocytopenia, serositis and vasculitis. Anti-nuclear antibody (ANA), anti-double stranded DNA...

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Main Authors: Baharuddin, Hazlyna, Mohd Zim, Mohd Arif, Rosman, Azmillah, Mohd Zain, Mollyza
Format: Article
Language:English
Published: Universiti Teknologi MARA Cawangan Selangor 2017
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/30064/
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author Baharuddin, Hazlyna
Mohd Zim, Mohd Arif
Rosman, Azmillah
Mohd Zain, Mollyza
author_facet Baharuddin, Hazlyna
Mohd Zim, Mohd Arif
Rosman, Azmillah
Mohd Zain, Mollyza
author_sort Baharuddin, Hazlyna
building UiTM Institutional Repository
collection Online Access
description Here we present a 24-year-old lady with systemic lupus erythematosus (SLE) whom we diagnosed with shrinking lung syndrome (SLS), a rare manifestation of SLE. The initial SLE manifestation was alopecia, thrombocytopenia, serositis and vasculitis. Anti-nuclear antibody (ANA), anti-double stranded DNA (dsDNA) antibody, anti-ribonucleic (RNP) and anti-Ro antibody were positive. A year after diagnosis, she started to develop intermittent dyspnea and was hospitalised on three occasions. Lung examinations revealed reduced breath sounds at both bases and dullness at the right base. Multiple chest radiographs showed bilateral raised hemi-diaphragms. Other investigations including CT pulmonary angiogram, high resolution CT of the thorax, ventilation-perfusion scan and echocardiogram were not significant. On the third hospital admission, we noticed bilateral small lung volumes in the previous high resolution CT scan. Inspiratory and expiratory chest radiographs were performed and showed minimal change in lung volumes and a diagnosis of shrinking lung syndrome (SLS) was made. Her SLE remained active with lupus nephritis despite multiple immunosuppression and she passed away two years later due to sepsis with multi-organ failure.
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spelling uitm-300642020-04-22T02:06:47Z https://ir.uitm.edu.my/id/eprint/30064/ Shrinking Lung Syndrome – A rare cause of recurrent dyspnoea in SLE / Hazlyna Baharuddin … [et al.] jchs Baharuddin, Hazlyna Mohd Zim, Mohd Arif Rosman, Azmillah Mohd Zain, Mollyza Specialties of internal medicine Diseases of the lungs Here we present a 24-year-old lady with systemic lupus erythematosus (SLE) whom we diagnosed with shrinking lung syndrome (SLS), a rare manifestation of SLE. The initial SLE manifestation was alopecia, thrombocytopenia, serositis and vasculitis. Anti-nuclear antibody (ANA), anti-double stranded DNA (dsDNA) antibody, anti-ribonucleic (RNP) and anti-Ro antibody were positive. A year after diagnosis, she started to develop intermittent dyspnea and was hospitalised on three occasions. Lung examinations revealed reduced breath sounds at both bases and dullness at the right base. Multiple chest radiographs showed bilateral raised hemi-diaphragms. Other investigations including CT pulmonary angiogram, high resolution CT of the thorax, ventilation-perfusion scan and echocardiogram were not significant. On the third hospital admission, we noticed bilateral small lung volumes in the previous high resolution CT scan. Inspiratory and expiratory chest radiographs were performed and showed minimal change in lung volumes and a diagnosis of shrinking lung syndrome (SLS) was made. Her SLE remained active with lupus nephritis despite multiple immunosuppression and she passed away two years later due to sepsis with multi-organ failure. Universiti Teknologi MARA Cawangan Selangor 2017-06 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/30064/1/AJ_HAZLYNA%20BAHARUDDIN%20JCHS%20B%2017.pdf Baharuddin, Hazlyna and Mohd Zim, Mohd Arif and Rosman, Azmillah and Mohd Zain, Mollyza (2017) Shrinking Lung Syndrome – A rare cause of recurrent dyspnoea in SLE / Hazlyna Baharuddin … [et al.]. (2017) Journal of Clinical and Health Sciences <https://ir.uitm.edu.my/view/publication/Journal_of_Clinical_and_Health_Sciences.html>, 2 (1). pp. 1-4. ISSN 0127-984X https://jchs-medicine.uitm.edu.my/index.php
spellingShingle Specialties of internal medicine
Diseases of the lungs
Baharuddin, Hazlyna
Mohd Zim, Mohd Arif
Rosman, Azmillah
Mohd Zain, Mollyza
Shrinking Lung Syndrome – A rare cause of recurrent dyspnoea in SLE / Hazlyna Baharuddin … [et al.]
title Shrinking Lung Syndrome – A rare cause of recurrent dyspnoea in SLE / Hazlyna Baharuddin … [et al.]
title_full Shrinking Lung Syndrome – A rare cause of recurrent dyspnoea in SLE / Hazlyna Baharuddin … [et al.]
title_fullStr Shrinking Lung Syndrome – A rare cause of recurrent dyspnoea in SLE / Hazlyna Baharuddin … [et al.]
title_full_unstemmed Shrinking Lung Syndrome – A rare cause of recurrent dyspnoea in SLE / Hazlyna Baharuddin … [et al.]
title_short Shrinking Lung Syndrome – A rare cause of recurrent dyspnoea in SLE / Hazlyna Baharuddin … [et al.]
title_sort shrinking lung syndrome – a rare cause of recurrent dyspnoea in sle / hazlyna baharuddin … [et al.]
topic Specialties of internal medicine
Diseases of the lungs
url https://ir.uitm.edu.my/id/eprint/30064/
https://ir.uitm.edu.my/id/eprint/30064/