Prevalence and factors associated with dysglycemia in chronic obstructive pulmonary disease (COPD) patients with and without exacerbations / Khairil Khuzaini Zulkifli

Background and Aims: Dysglycemia, consisting of diabetes mellitus (DM), impaired glucose tolerance (IGT) and impaired fasting glucose (IFG), is a common comorbid of COPD. High prevalence of dysglycemia in COPD is well-recognized, however data comparing COPD exacerbation with incidence of dysglycemia...

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Main Author: Zulkifli, Khairil Khuzaini
Format: Thesis
Language:English
Published: 2017
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/27614/
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author Zulkifli, Khairil Khuzaini
author_facet Zulkifli, Khairil Khuzaini
author_sort Zulkifli, Khairil Khuzaini
building UiTM Institutional Repository
collection Online Access
description Background and Aims: Dysglycemia, consisting of diabetes mellitus (DM), impaired glucose tolerance (IGT) and impaired fasting glucose (IFG), is a common comorbid of COPD. High prevalence of dysglycemia in COPD is well-recognized, however data comparing COPD exacerbation with incidence of dysglycemia is scarce. Thus, this study aimed to determine whether COPD exacerbation is a risk factor for dysglycemia. Materials and Methods: This is a cross-sectional study involving patients with established COPD aged 30 years and above (n=186) attending respiratory specialist clinics in UiTM campuses. Those on long-term corticosteroid therapy, active malignancy or in peripartum periods were excluded. Patients were divided into those with or without hospital admission for exacerbation in the past year. All participants had glycated hemoglobin level and inflammatory marker Interleukin-6 (IL-6) concentration assessment, and patients with no prior diagnosis of dysglycemia underwent oral glucose tolerance test (OGTT).
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spelling uitm-276142020-02-05T04:41:03Z https://ir.uitm.edu.my/id/eprint/27614/ Prevalence and factors associated with dysglycemia in chronic obstructive pulmonary disease (COPD) patients with and without exacerbations / Khairil Khuzaini Zulkifli Zulkifli, Khairil Khuzaini Specialties of internal medicine Background and Aims: Dysglycemia, consisting of diabetes mellitus (DM), impaired glucose tolerance (IGT) and impaired fasting glucose (IFG), is a common comorbid of COPD. High prevalence of dysglycemia in COPD is well-recognized, however data comparing COPD exacerbation with incidence of dysglycemia is scarce. Thus, this study aimed to determine whether COPD exacerbation is a risk factor for dysglycemia. Materials and Methods: This is a cross-sectional study involving patients with established COPD aged 30 years and above (n=186) attending respiratory specialist clinics in UiTM campuses. Those on long-term corticosteroid therapy, active malignancy or in peripartum periods were excluded. Patients were divided into those with or without hospital admission for exacerbation in the past year. All participants had glycated hemoglobin level and inflammatory marker Interleukin-6 (IL-6) concentration assessment, and patients with no prior diagnosis of dysglycemia underwent oral glucose tolerance test (OGTT). 2017 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/27614/1/TM_KHAIRIL%20KHUZAINI%20ZULKIFLI%20MD%2017_5.pdf Zulkifli, Khairil Khuzaini (2017) Prevalence and factors associated with dysglycemia in chronic obstructive pulmonary disease (COPD) patients with and without exacerbations / Khairil Khuzaini Zulkifli. (2017) Masters thesis, thesis, Universiti Teknologi MARA. <http://terminalib.uitm.edu.my/27614.pdf>
spellingShingle Specialties of internal medicine
Zulkifli, Khairil Khuzaini
Prevalence and factors associated with dysglycemia in chronic obstructive pulmonary disease (COPD) patients with and without exacerbations / Khairil Khuzaini Zulkifli
title Prevalence and factors associated with dysglycemia in chronic obstructive pulmonary disease (COPD) patients with and without exacerbations / Khairil Khuzaini Zulkifli
title_full Prevalence and factors associated with dysglycemia in chronic obstructive pulmonary disease (COPD) patients with and without exacerbations / Khairil Khuzaini Zulkifli
title_fullStr Prevalence and factors associated with dysglycemia in chronic obstructive pulmonary disease (COPD) patients with and without exacerbations / Khairil Khuzaini Zulkifli
title_full_unstemmed Prevalence and factors associated with dysglycemia in chronic obstructive pulmonary disease (COPD) patients with and without exacerbations / Khairil Khuzaini Zulkifli
title_short Prevalence and factors associated with dysglycemia in chronic obstructive pulmonary disease (COPD) patients with and without exacerbations / Khairil Khuzaini Zulkifli
title_sort prevalence and factors associated with dysglycemia in chronic obstructive pulmonary disease (copd) patients with and without exacerbations / khairil khuzaini zulkifli
topic Specialties of internal medicine
url https://ir.uitm.edu.my/id/eprint/27614/